Muscles Flashcards

1
Q

this type of muscle is multinucleated, contains mitochandria, is mainly voluntary, and its basic contractile unit is a sarcomere

A

skeletal muscle

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2
Q

true or false- the number of skeletal muscle fibers is set before you are born

A

true

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3
Q

enlargement of existing muscle fibers

A

hypertrophy

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4
Q

shrinkage of existing muscle fibers

A

atrophy

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5
Q

these two hormones stimulate hypertrophy

A

testosterone and GH

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6
Q

This motor protein makes up thick filaments

A

myosin

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7
Q

what are the 3 components of thin filaments in skeletal muscle?

A

actin
troponin
tropomyosin

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8
Q

what are the 3 subunits of troponin?

A

T- attaches to tropomyosin
I- inhibits binding of actin and myosin
C- binds calcium

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9
Q

These are two structure proteins in skeletal muscle that hold the filaments together and anchor them to the cell membrane

A

titin and dystrophin

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10
Q

what is the basic contractile units of skeletal muscle?

A

sarcomere

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11
Q

This is a voltage sensor in skeletal muscle that activates ryanodine receptors, allowing Ca2+ release

A

dihydropyridine (DHP)

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12
Q

this receptor forms a Ca2+ channel

A

Ryanodine receptor

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13
Q

What part of the thin filament blocks myosin from binding actin?

A

tropomyosin

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14
Q

________ occurs when Ca2+ is pumped back into the SR

A

relaxation

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15
Q

at neuromusclular junctions, motor neurons release ________ and it attaches to _______ ____ receptors

A

ACh; nicotinic ACh

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16
Q

this results from a single AP resulting in a fixed amount of Ca2+ release

A

twitch

17
Q

this occurs due to a sustained contraction because of the repeated firing of a motor neuron

A

tetanus

18
Q

this type of contraction occurs when the muscle contracts but does not shorten

A

isometric

19
Q

this type of contraction occurs when the muscle changes length but the force remains the same

A

isotonic

20
Q

This type of muscle is spindle-shaped, can divide throughout the lifetime, has a single nucleus and lacks troponin

A

smooth muscle

21
Q

This type of muscle’s thin filaments are anchored to the plasma membrane or to dense bodies

A

smooth muscle

22
Q

This is the molecule that Ca2+ binds to in smooth muscle

A

calmodulin

23
Q

what molecule does calcium calmodulin activate?

A

myosin light chain kinase (MLCK)

24
Q

What is the function of MLCK in smooth muscle?

A

phosphorylation of myosin, which allows the binding to actin

25
Q

What enzyme is responsible for the dephosphorylation of myosin in smooth muscle?

A

myosin light-chain phosphatase (MLCP)