Adaptive Immunity Flashcards
what are the 2 major APCs in the innate immune system?
macrophages and dendritic cells
what are the 2 major cell types of the adaptive immune system?
B and T cells
where are lymphocytes (B and T cells) primarily found?
lymph nodes
are NK cells part of the innate or adaptive?
innate
this part of the immune system recognizes PAMPs and is nonspecific
innate
this part of the immune system recognizes antigens and is specific
adaptive
this term refers to the fact that subsequent exposures to a pathogen are faster and more intense upon repeated exposure
memory
this adaptive strategy kills free-floating pathogens
humoral
this adaptive strategy kills pathogens hiding inside cells
cell mediated
what is the major cell type responsible for the adaptive cell mediated strategy?
CD-8 cytotoxic t cells
this process ensures B and T cells can distinguish self from non-self
negative selection
where do B cells go through negative selection?
bone marrow
where do T cells go through negative selection?
thymus
this region of Ig is what is continuously altered to detect pathogenic antigens
variable region
these are described as anything that induces an immune response
antigens
this is a specific part of the antigen that the immune system recognizes
epitope
many epitopes on a single antigen is referred to as…
polyclonal