Electrophysiology Flashcards
cardiac muscle features
intercalated disks
gap junctions
striated
involuntary
most superfical layer of the heart, it’s the visceral layer of the serous pericardium
epicardium
this is the middle layer of the heart, it’s composed of cardiac muscle and is the layer that contracts. It contains gap junctions.
myocardium
this is the inner layer of the heart which is continuous with the lining of the blood vessels
endocardium
true or false- every heart cell contracts with every beat of the heart
true
can the heart replace its muscle cells?
yes, but it is very limited
only about 1% per year
this is a small group of cells that depolarize spontaneously and the AP spreads through gap junctions in intercalated discs
conducting/ pacemaker cells
list the order of the pacemaker activation sequence
SA node
AV node
Bundle of His
Left and right branches
Purkinje fibers
SA node firing rate
70-80
AV node firing rate
40-60
Bundle of His firing rate
30-40
Purkinje fiber firing rate
15-20
are cardiac AP shorter or longer than skeletal or neuronal?
longer
nodal cells have _____ which means they spontaneously generate APs
Automaticity
explain 3 nodal depolarization events
1- slow Na+ through funny channels
2- T-type Ca2+ channels open
3- L-type Ca2+ channels open–> rapid depolarization
explain nodal repolarization
Ca2+ channels close
K+ channels open and K+ rushes out leading to repolarization
what is Bachmann’s bundle?
atrial projections for intratrial communication
what is the only path to the ventricles from the SA node?
internodal tracts to the AV node
which node has a pause?
AV node