muscle relaxers

Question 1

what are the 2 types of muscle relaxers

Answer 1

1) Antispastic
2) Antispasm (spasmotics/polysynaptic)

Question 2

what are the generalized adverse effects of antispastics

Answer 2

muscle weakness and sedation

Question 3

what are the general conditions that antispastic drugs treat

Answer 3

CNS conditions: such as CP, MS, CVA, MS, SCI

Question 4

what are the antispastic drugs

Answer 4

1) Baclofen
2) Diazepam
3) Tizanidine
4) Dantrolene
5) Botulinum toxin

Question 5

MOA of baclofen

Answer 5

Gaba B agonist

Question 6

MOA of Diazepam

Answer 6

Gaba A agonist

Question 7

MOA of Tizanidine

Answer 7

alpha 2 adrenergic

Question 8

MOA of Dantrolene

Answer 8

blocks ca2 release at the neuromuscular junction

Question 9

MOA of Botulinum

Answer 9

decrease in AcH

Question 10

what is an addition condition that Tizanidine is used to treat

Answer 10

ALS

Question 11

what is an additional side effect of Tizanidine

Answer 11

hypotension

Question 12

what is an additional side effect of diazepam

Answer 12

coma or death - can use Flumazenil to counteract OD.

Question 13

List of anti-spasm drugs

Answer 13

1) Carisoprodol
2) Cyclobenzaprine
3) Metacarbamol
4) Orphenadrine