Drug for PD Flashcards
Drugs that can cause drug induced PD
drugs used for nausea and psychosis that block dopamine blockers end in (-azine, -idol, -idone and metoclopramide)
classes of drugs used in PD
1) Dopamine agonists
2) Dopamine precursor and related agents
3) Monoamine oxidase (MAO) inhibitors
4) Catechol-O-Methyl-Transferance (COMT) inhibitors
5) Amantadine
what are the drugs that make use of the dopamine agonist class
1) Pramipexole
2) Ropinirole
3) Rotigotone
what is a D3 agonist
Pramipexole
what is a D2 agonist
Ropinirole and Rotigotone
what are the side effects of dopamine agonists
- sedation
- hallucinations
- confusion
- orthostatic Hypotension
- dyskinesias
what are the drugs that are in the dopamine precursor and related agents class
levadopa and carbidopa together in a pill is sinemet
what is the MOA of levadopa
dopamine precursor
what is the MOA of carbidopa
Dopa decaroboxylase (DCC) inhibitor
what is the side effects of levadopa and carbidopa
- GI issues
- arrhythmias
- dyskinesias
- on and off patterns
- behavioral disturbances
what drugs are in the Monoamine Oxidase (MAO) inhibitor class
-giline and safinamide
what is the MOA of MAO inhibitors
Monoamine oxidase B inhibitor preventing the dopamine breakdown in the brain
what are the side effects of MOA inhibitors
- serotonin syndrome
what drugs are in the COMT inhibitor drug class
(-capone)
what is the MOA of the COMT inhibitors
inhibit Catechol-O-methyl transferase both peripherally and in the brain
