Drugs for MS

Question 1

what are the 2 immune cells involved in MS

Answer 1

B-cells and T-cells

Question 2

what do B cells and T cells do

Answer 2

attack myeline sheath in CNS causing inflammation and axonal damage

Question 3

what are the 4 forms of MS

Answer 3

1) relapsing remitting
2) secondary progressive
3) primary progressive
4) progressive relapsing

Question 4

what is the only FDA approved drug for the exasterbation of MS

Answer 4

adrenocroticotropic hormone (ACTH)

Question 5

what are the injectable medications for modifying disease progression in MS

Answer 5

interferon beta-1
interferon beta 2
Glatiramer Acetate

Question 6

what are the orally administered drugs for modifying disease progression of MS

Answer 6

1) Fingolimod
2) dimethyl fumarate

Question 7

what are the infused drugs for mondifying disease progression of MS

Answer 7

1) mitoxantrone
2) ocrelizumab
3) natalizumab

Question 8

MOA of ocrelizumab

Answer 8

humanized immunoglobin antibody (FDA approved), primary progressive

Question 9

what are the drugs that are used to manage fatigue in MS

Answer 9

1) amantadine
2) methylphenidate

Question 10

what are the drugs used to manage spasticity in MS

Answer 10

1) baclofen
2) dantrolene
3) tizanidine

Question 11

what are the drugs to control bladder issues in MS

Answer 11

1) oxybutynin
2) prazosin

Question 12

what are the drugs used to manage sensory S/S in MS

Answer 12

1) gabapentin
2) pregabalin

Question 13

common side effects of MS drugs

Answer 13

• muscle weakness
• fatigue
• dizziness
• heat sensitivity
• decreased cognitive dysfunction
• dizziness