Drugs for Asthma and COPD

Question 1

drugs for ASTHMA

Answer 1

A= adrenergics
S= steroids
T= Theophylline
H= hydration and O2 supplementation
M= Laukotrine modifiers
A= anticholinergic

Question 2

what are the short acting beta 2 agonists

Answer 2

albuterol and levabuterol

Question 3

what is the common MOA of beta 2 agonists

Answer 3

brochodilation

Question 4

what are the common side effects of beta 2 agonists

Answer 4

tachycardia, palpitations, tremors, nervousness

Question 5

what are the long acting beta agonists

Answer 5

salmeterol and formoterol

Question 6

what are the clinical use for short acting beta 2 agonists

Answer 6

actue asthma S/S

Question 7

what are the clinical use for long acting beta 2 agonist

Answer 7

long term ashma use

Question 8

what is the suffix for corticosteroids

Answer 8

( sone or sonide)

Question 9

what is the MOA of corticosteriords

Answer 9

anti-inflammatory; reduce airway inflammation

Question 10

what is the clinical use for corticosteroids for asthma pts

Answer 10

maintenance therapy to prevent exasterbations

Question 11

what are the side effects for corticosteriods

Answer 11

• oral thrush
• osteoporosis
• wt gain
• increased risk for infection
• muscle wasting

Question 12

what is the MOA of theophylline

Answer 12

caffeine use to relax bronchi

Question 13

what is the suffix for leukotrine modifiers

Answer 13

leukotriene receptor agonist (-lukast)
5-lipoxygenase inhibitor (zileuton)

Question 14

what is the MOA of leukotriene modifiers

Answer 14

block leukotriene receptors or inhibit their synthesis

Question 15

what are the side effects for leukotriene modifiers

Answer 15

• headache
• nausea
• mood changes

Question 16

what are the drugs that are anticholinergic

Answer 16

the bromide bros (tio last longer)

Question 17

what is the MOA of anticholinergic drugs

Answer 17

inhibit M receptors which leads to a lack of vasoconstriction

Question 18

what are the side effects of anticholinergic drugs

Answer 18

• dry mouth
  -cough
• urinary retention
• blurred vision
• constipation
• tachycardia

Question 19

what is the MOA of mast cell stabilizers

Answer 19

prevent the release of inflammatory mediator from mast cells

Question 20

what is the clinical use for mast cell stabilizers

Answer 20

treatment for children with asthma

Question 21

what are the side effects of mast cell stabilizers

Answer 21

• cough
• throat irritation
• rare allergic reactions

Question 22

what is the clinical use for theophylline

Answer 22

chronic asthma

Question 23

what are the side effects of theophylline

Answer 23

• insomnia
• gastric upset
• tachycardia
• seizures

Question 24

what is the MOA of monoclonal antibodies

Answer 24

target and neutralize specific immune pathways

Question 25

what is the clinical implication for monoclonal antibodies

Answer 25

severe allergic asthma

Question 26

what are the side effects of monoclonal antibodies

Answer 26

• injection site reaction
• potential anaphylaxis

Question 27

what are the classes of medications that can be used for COPD

Answer 27

• bronchodilators (beta agonists and anticholinergic)
• steroids
• phosphodiesterase 5 inhibitors
• O2 therapy

Question 28

what is a phosphodiesterase 5 inhibitor drug

Answer 28

Roflumilast

Question 29

what is the MOA of Roflumilast

Answer 29

decrease inflammation by inhibiting phosphodiesterase 5

Question 30

what is the clinical use for Roflumilast

Answer 30

decrease risk for COPD exasterbation

Question 31

what are the side effects of Roflumilast

Answer 31

• wt loss
• diarrhea
• nausea
• headache
• insominia