Module 5 - Pain Unit A

Question 1

Indications of aspirin

Answer 1

Post MI
protection against clotting disorders
fever
mild-moderate pain
anti-inflammatory for RA, Tendinitis, Bursitis

Question 2

Contraindications of aspirin

Answer 2

Under 19 years old during a fever - can lead to Reye’s syndrome.
Do not give higher doses in pregnancy - category D

Question 3

Contraindications of NSAIDs

Answer 3

Pregnancy
Hx of MI
Cautions with corticosteroids, anticoagulants, ASA, alcohol

Question 4

BBW for NSAIDs

Answer 4

Increased risk of GI bleed, CV events, hospitalization, death

Question 5

what is cyclooxygenase (COX)

Answer 5

An enzyme that converts arachidonic acid to prostaglandins or leukotrienes

Question 6

Non-selective NSAID

Answer 6

Naproxen (Aleve)

Question 7

COX-2 inhibitor

Answer 7

Celecoxib (Celebrex)

Question 8

Celebrex contraindication

Answer 8

Hx of MI or current unstable angina, increases risk of CV issues

Question 9

Use with caution in diabetics

Answer 9

Celebrex

Question 10

Major concern with APAP

Answer 10

Liver toxicity

Question 11

Tylenol MOA

Answer 11

NOT an NSAID- does not inhibit COX well in the presence of inflammation - in the periphery.
Inhibits COX in CNS reducing fever and pain.