antibiotics 2 Flashcards
Increases tendon rupture if older than 60, if. taking corticosteroids, and patients with organ transplants
fluoroquinolone (Levaquin)
Combination increases INR an average of 1.76 times
Trimethoprim-sulfamethoxazole (Bactrim)
sulfonamide
More drugs that increase INR
Erythromycin, fluconazole, ketoconazole, itraconazole, metronidazole
Associated with hyperkalemia
Trimethoprim-sulfamethazole (Bactrim)
Do not use with Metals
tetracycline
Best choice for treatment of UTI in pregnancy (if penicillins and cephalosporins are not able to be used)
Macrobid (nitrofurantoin) -
Check for G6PD deficiency first
Try to avoid in first and third trimesters of pregnancy
Sulfonamide (Bactrim)
Use to treat symptomatic BV during pregnancy during any trimester
oral metronidazole
be cautious about disulfiram reaction-
Abstain from alcohol during treatment and for 24-48 hours before and after
metronidazole
Name the two approved influenza antivirals
- Oseltamivir (Tamiflu)
2. Zanamivir (Relenza)
How to tamiflu and relenza work
Block neuroamindase to prevent replication
Interferes with viral RNA transcription
Baloxavir marboxil (Xofluza)
High risk individuals for flu
Age less than 2 or older than 65, people with chronic conditions, pregnant or postpartum women, children less than 19, long-term aspirin therapy, immunosuppressed