antibiotics 2 Flashcards

1
Q

Increases tendon rupture if older than 60, if. taking corticosteroids, and patients with organ transplants

A

fluoroquinolone (Levaquin)

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2
Q

Combination increases INR an average of 1.76 times

A

Trimethoprim-sulfamethoxazole (Bactrim)

sulfonamide

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3
Q

More drugs that increase INR

A

Erythromycin, fluconazole, ketoconazole, itraconazole, metronidazole

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4
Q

Associated with hyperkalemia

A

Trimethoprim-sulfamethazole (Bactrim)

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5
Q

Do not use with Metals

A

tetracycline

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6
Q

Best choice for treatment of UTI in pregnancy (if penicillins and cephalosporins are not able to be used)

A

Macrobid (nitrofurantoin) -

Check for G6PD deficiency first

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7
Q

Try to avoid in first and third trimesters of pregnancy

A

Sulfonamide (Bactrim)

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8
Q

Use to treat symptomatic BV during pregnancy during any trimester

A

oral metronidazole

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9
Q

be cautious about disulfiram reaction-

Abstain from alcohol during treatment and for 24-48 hours before and after

A

metronidazole

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10
Q

Name the two approved influenza antivirals

A
  1. Oseltamivir (Tamiflu)

2. Zanamivir (Relenza)

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11
Q

How to tamiflu and relenza work

A

Block neuroamindase to prevent replication

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12
Q

Interferes with viral RNA transcription

A

Baloxavir marboxil (Xofluza)

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13
Q

High risk individuals for flu

A

Age less than 2 or older than 65, people with chronic conditions, pregnant or postpartum women, children less than 19, long-term aspirin therapy, immunosuppressed

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