MMB (035) Practical of Bone and Soft tissue tumors 2 Flashcards
What is the diagnosis?
Osteoma
Osteoma
Discuss the benign features of this tumor
What is the diagnosis?
Describe the histological findings
What are the three microscopic types of osteosarcoma?
Osteoblastic
Chondroblastic
Fibroblastic
What is the likely route of metastasis of osteosarcoma?
• Early metastasis to lungs and bones
What is the prognosis of osteosarcoma?
Bad prognosis
Early metastasis to lungs and bones The 5-year survival rate is 5-20% Radiation therapy has proven ineffective
Indicate common sites of chondroma occurrence
What is the prognosis of chondrosarcoma?
Slowly growing tumor, can remain locally aggressive for many years with a high tendency to recur after excision and implant in soft tissues.
Blood dissemination to the lungs, liver and kidneys.
The 5-years survival rate for grades I, II, III are 90%, 81%, 43% respectively and the 10-years survival rate is 50-60%.
What are the common sites of chondrosarcoma?
Common sites of chondrosarcoma :
Central skeleton (spine, pelvis, ribs, sternum and scapula)
Lower end of femur and upper end of tibia and humerus.
Etiological types of chondrosarcoma ?
• Primary chondrosarcoma (arises de novo in 75% of tumors)
• Secondary chondrosarcoma (in 25%, from preexisting benign cartilaginous lesions (e.g. enchondroma)
What is the most likely diagnosis?
Ewing sarcoma ; primitive or peripheral neuro-ectodermal tumor (PNET)
15 years old boy recently discovered thigh swelling which is rapidly growing in size within a week, MRI shows intramuscular mass with
remarkable necrotic changes
Rhabdomyosarcoma ;
What is the behavior and prognosis of this tumor?
How can you manage this case?
