MMB (024) Degenerative Joint Disease

Question 1

Answer 1

Question 2

Answer 2

Question 3

Answer 3

Question 4

Answer 4

Question 5

Answer 5

Question 6

Mention the pathological feature present in this microscopy of arthritic cartilage

Answer 6

Question 7

What’s the Tidemark ?

Answer 7

Junction of articular cartilage and subchondral bone (zone of calcified cartilage)

Question 8

Define the hidden , and mention the pathological features indicating osteoarthritis

Answer 8

Question 9

comment on this symbolic photo

Answer 9

Question 10

comment on this figure of osteoarthriric femural head

Answer 10

There is marked irregularity and erosion of the articular surface. Very little articular cartilage remains

Question 11

comment on this figure of osteoarthriric femural head

Answer 11

Question 12

Define the hidden , and mention the pathological features indicating osteoarthritis

Answer 12

Question 13

What’s meant by flaking in the process of osteoarthritis ?

Answer 13

Loss of proteoglycans

Question 14

How can flaking (loss of proteoglycans) in arthritis be detected by microscopy ?

Answer 14

Toluidine blue stain ;

-It stains nuclei red, proteoglycans purple

Question 15

What’s Eburnation ?

Answer 15

Eburnation is described as a specific type of bone sclerosis consisting of a marbled appearance of weight-bearing joints with complete cartilaginous erosion, leaving polished, sclerotic bone as the new articular surface bone

Question 16

Osteoarthritis pathogenesis steps ?

Answer 16

Question 17

Answer 17

Question 18

Name the two pathological lesions shown , and mention how they can be diffriniated from each other

Answer 18

-Bouchard’s nodes ;
bony swellings in PIP joints

-Heberden’s nodes ;
bony swellings in DIP joints

Question 19

Define the two pathological features pointed to in the x-ray

Answer 19

Question 20

Four radiological features of osteoarthritis ?

Answer 20

Question 21

Answer 21

Question 22

5 Osteoarthritis Signs & Symptoms ?

Answer 22

1) Pain aggravated by movement and relieved by rest

2) Morning stiffness is common but it is minimal and quickly subsides lasting less than 30 minutes

3) Crepitus on movement

4) Limitation of movement

5) Compression of spinal nerve roots

Question 23

Answer 23

Question 24

Define Hip Dysplasia

Answer 24

Question 25

Define Perthe’s disease

Answer 25

Hip disorder characterized by osteonecrosis of femoral head due to compromised blood supply.

Question 26

Congenital Causes of Perthe’s disease ?

Answer 26

Congenital dislocation of the hip

Question 27

Acquired Causes of Perthe’s disease ?

Answer 27

• Traumatic – fracture

• Infective

• Neoplastic

• Blood / Biochemical – gout, haemochromatosis

• Endocrine – diabetes mellitus (peripheral neuropathy)

• Degenerative – overuse

Question 28

What is the meme “CAT IN BED” used to memorize ?

Answer 28