Metaproterenol

Question 1

Metaproterenol- Name

Answer 1

Alupent

Metaprel

Question 2

Metaproterenol- Class

Answer 2

Sympathomimetic Bronchodilator

Question 3

Metaproterenol- MoA

Answer 3

Selective Beta2 agonist

Relaxes bronchial smooth muscle

Inhibits histamine release from mast cells, reducing mucus production, capillary leaking and mucosal edema caused by allergic reaction in lungs

Question 4

Metaproterenol- Indication

Answer 4

Asthma Bronchospasms

associated with COPD Allergic reaction/anaphylaxis

Question 5

Metaproterenol- Contra

Answer 5

Narrow angle glaucoma

cardiac dysrhythmias associated with tachycardia

Question 6

Metaproterenol- S/E

Answer 6

Cardiovascular: palpitations, tachydysrhythmias, hypertension

CNS: nervousness, weakness, drowsiness, tremors

Question 7

Metaproterenol- Routes

Answer 7

Nebulized and inhaled, HHN (hand held nebulizer)

Question 8

Metaproterenol- A. Dose

Answer 8

10-15 mg (0.2-0.3 mL of a 5% solution),

dilute in 2.5 mL of NS every 4 hours

Question 9

Metaproterenol- P. Dose

Answer 9

0.5 to 1 mg/kg (0.01 to 0.02 mL/kg of 5% solution);

dilute in 3 mL NS

(age > 5 yrs) minimum dose: 5 mg (0.1 mL); maximum dose: 15 mg (0.3 mL); every 4 hours

Question 10

Metaproterenol- EXTRAS

Answer 10

Precautions:

Pregnancy

Cardiac disease

Diabetes

Interactions:

Other sympathomimetics will potentiate the effects

Beta blockers will decrease actions

Onset in 5 minutes and may last 4 hours