Dopamine Flashcards
Dopamine- Name
Intropin
Dopamine- Class
Sympathomimetic,
Catecholamine,
Vasopressor
Dopamine- MoA
Low Dose or Renal/Mesenteric Dose (1-5 mcg/kg/min):
Dilates renal and mesenteric arteries by stimulating dopaminergic receptors Increases urinary output
Moderate Dose or Inotropic Dose (5-10 mcg/kg/min):
Increases inotropy without increasing chronotropy Increases blood pressure by stimulating the beta1 receptors
High Dose or Vasopressor Dose (10-20 mcg/kg/min):
Causes vasoconstriction (alpha); increasing blood pressure Increase inotropy and chronotropy (beta 1); increasing blood pressure
Dopamine- Indications
Cardiogenic shock
Distributive shock after fluids
Hemodynamically significant hypotension
Symptomatic bradycardia (second line drug)
Dopamine- Contra
Hypovolemia
Tachydysrhythmias
Hyperthermia
Dopamine- S/E
(all dose-dependent):
Cardiovascular: tachycardia, hypertension/hypotension, chest pain, ventricular irritability Respiratory: dyspnea
Dopamine- Routes
IVPB
Dopamine- A. Dose
Low dose: 1-5 mcg/kg/min
Moderate dose: 5-10 mcg/kg/min
High dose: 10-20 mcg/kg/min
Dopamine- P. Dose
Low dose: 1-5 mcg/kg/min
Moderate dose: 5-10 mcg/kg/min
High dose: 10-20 mcg/kg/min
Dopamine- EXTRAS
Precautions: Cannulate largest vein possible and ensure IV patency (necrotic)
Start a second IV line if additional medications are needed (Dopamine infusion should not be interrupted, to ensure adequate therapeutic blood levels)
Interactions: Flush tubing before and after administration of Sodium Bicarbonate as Dopamine will be inactivated by the change in pH
Actions may be intensified if patient is also taking antidepressants
May cause hypotension if patient taking phenytoin (Dilantin®㋿)
Onset in 5 minutes and will last 3-5 minutes
\Flow rate determines which receptor sites are stimulated and results in a graded response
Frequent vital signs are required for all patients with a Dopamine infusion
Once appropriate blood pressure is achieved, infusion may need to be slowed but should not be stopped
