Adenosine Flashcards
Adenosine- name
Adenocard
Adenosine- class
Antidysrhythmic
Endogenous nucleoside
Adenosine- MoA
Slows conduction of the SA and AV nodes
Can interrupt reentry pathways through the AV and SA nodes
Adenosine- Indications
SVT or PSVT unresponsive to Valsalva (vagal) maneuvers
- Wide complex tachycardia as diagnostic drug (not used for torsades)
Adenosine- Contra
23 H S
2nd or 3rd degree heart block
Hypovolemia – do not give adenosine prior to fluid administration
Sick Sinus Syndrome
Adenosine- S/E
Cardiovascular: 23 ABC HT(p)
2nd or 3rd degree heart blocks
asystole, bradycardia, chest pain/pressure
hypotension, transient PACs/PVCs,
Neurological: seizures, blurred vision, tingling/numbness, dizziness
Respiratory: shortness of breath/dyspnea, respiratory failure
Gastrointestinal: nausea, metallic taste Other: flushed skin
Adenosine- Routes
Rapid IVP or IO
Adenosine- A. Dose
6 mg rapid IVP/IO followed by 10-20 ml flush
May repeat with 12 mg twice after 1-2 minutes each
Adenosine- P. Dose
0.1 mg/kg rapid IVP/IO followed by 10 ml flush
May repeat with 0.2 mg/kg twice after 1-2 minutes
Adenosine- EXTRAs
Precautions: Cannulate largest vein possible (and no smaller than 20 gauge IV catheter) to facilitate rapid flush following drug administration
Avoid administration with patients with bronchoconstriction or bronchospasms
Use very cautiously in COPD patients (i.e. those with emphysema or chronic bronchitis) due to respiratory failure side effect
Check current home medications prior to administration
Interactions: Patient use of methyl-xanthines (i.e. Theophylline or caffeine) may render drug ineffective
Patients taking carbamazepine (Tegretol) or dipyridamole (Persantine) as both will intensify effects
Onset is immediate and will last less than 10 seconds
For a poorly perfusing, symptomatic patient, consider cardioversion prior to Adenosine
