Ipratropium Bromide

Question 1

Ipratropium Bromide- Name

Answer 1

Atrovent

Question 2

Ipratropium Bromide- Class

Answer 2

Anticholinergic (Parasympatholytic)

Bronchodilator

Question 3

Ipratropium Bromide- MoA

Answer 3

Inhibits interaction of acetylcholine at receptor sites on bronchial smooth muscle,

thereby allowing bronchodilation

Question 4

Ipratropium Bromide- Indication

Answer 4

Bronchospasms due to

COPD,

allergic reaction

asthma

refractory to other Beta2 agonists

Question 5

Ipratropium Bromide- Contra

Answer 5

Hypersensitivity to atropine, soybean or peanut products

Question 6

Ipratropium Bromide- S/E

Answer 6

Cardiovascular: palpitations

Other: dry mouth

Question 7

Ipratropium Bromide- Routes

Answer 7

Nebulized and inhaled: HHN, mask

Question 8

Ipratropium Bromide- A. Dose

Answer 8

0.5 mg mixed with 2.5 mg Albuterol

Question 9

Ipratropium Bromide- P. Dose

Answer 9

0.5 mg mixed with 5.0 mg Albuterol

and then administer only half of the volume

Question 10

Ipratropium Bromide- EXTRAS

Answer 10

Precautions: Not intended as a first line treatment for bronchospasm

Use with caution in those who are pregnant, lactating, or have a history of glaucoma, coronary artery disease or hypertension

Interactions: None

Onset in 15 minutes with peak effect at 1-2 hours, and may last 3-4 hours

Albuterol has a shorter time of onset, and should be used as the initial treatment