Mental Health 1 Flashcards
Depression is due to lack of what neurotransmitter?
Monoamine
What mechanism are phenelzine/ moclobemide?
Monoamine oxidase inhibitor
Name me drugs of SNRI ( selective serotonin and Noradrenaline reuptake inhibitor)?
Venlafaxine/ Desvenlafaxine/Duloxetine
Benefit - fewer anti-cholinergic side effect
What is Mirtazapine mechanism of action?
Monoamine receptor ANTAGONIST
Tricyclie antidepressants (amitryptyline - mechanism of action and side effect?
Selective serotonin and noradrenaline reuptake inhibitor
MOST ANTI-CHOLINERGIC SIDE EFFECT
Which drug has most effect on sexual libido and delayed ejaculation?
Setraline, SSRI ( fluoxetine/paroxetine/citalopram)
Which anti-depressant highest risk of prolong QT?
Citalopram
2nd is ziprasidone/haloperidol
What SSRI has unusually long half life and need washout period
Fluoxetine
Difference between ;
Looseness of association
flight of ideas
Word salad
Looseness of association
-unrelated topics but GRAMMAR CORRECT
Flight of ideas
-unrelated topics, high speech, manic
Word salad
- severe, don’t know what patient talking about - words doesn’t even exist
- can coin new words- neologisms
What is idea of reference and seen in what disorder?
Patient experience events that they believe related to them/directed to them
-Schizophrenia!
Main indication of ECT?
Severe catatonia of any cause
1st line is benzodiazepines
Strongest risk factor for suicide?
History of self-harm/suicide attempts
2nd - psychiatry disorders - depression/Schizophrenia
3rd -substance misuse/abuse
Most common psychotic disease?
Criteria to diagnose it?
Schizophrenia
Diagnosis 1 month of symptoms and > 6 months persistence of it -Delusions/hallucinations -Disorganised speech -Catatonia and negative symptoms
What is Schizoaffective?
Affective mood disorder BUT must have psychosis event without mood symptoms present
Best treatment for bipolar disorder?
Can that drug be used in pregnancy?
Lithium
Yes, ideally 2nd trimester onwards
