Hematology 5 Flashcards

1
Q

R-CHOP for DLBCL - main side effects?

A

Febrile neutropenia

can have Premature ovarian failure

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2
Q

DLBCL - has what CD?

A

CD19/20/22 - pan B cells

myc + BCL2-6 ( proteins ) - poor prognosis

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3
Q

Brentuximab mechanism of action?

A

Anti CD30

-attach to MMAE (tubulin) - convert to lysozyme and causes cell arrest (G2 to Mitosis)

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4
Q

Borrelia burgdorferi causes what type of lymphoma?

Hep C causes what type of lymphoma?

A

Cutaneous T cell lymphoma

Marginal Zone lymphoma

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5
Q

Radiotherapy increases risk of what cancer?

A

Breast
Thyroid
Lung

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