Hematology 5 Flashcards
1
Q
R-CHOP for DLBCL - main side effects?
A
Febrile neutropenia
can have Premature ovarian failure
2
Q
DLBCL - has what CD?
A
CD19/20/22 - pan B cells
myc + BCL2-6 ( proteins ) - poor prognosis
3
Q
Brentuximab mechanism of action?
A
Anti CD30
-attach to MMAE (tubulin) - convert to lysozyme and causes cell arrest (G2 to Mitosis)
4
Q
Borrelia burgdorferi causes what type of lymphoma?
Hep C causes what type of lymphoma?
A
Cutaneous T cell lymphoma
Marginal Zone lymphoma
5
Q
Radiotherapy increases risk of what cancer?
A
Breast
Thyroid
Lung