Mediastinum, Pleura and Organs of Respiration (Part 2) Flashcards
The mediastinum, though thick, is a movable partition that extends where? (borders)
Superior - thoracic outlet and root of the neck
Inferiorly - diaphragm
Anterior - sternum
Posterior - vertebral column
What does the mediastinum contain?
(10) remnants of thymus heart and large blood vessels trachea and esophagus thoracic duct and lymph nodes vagus and phrenic nerves sympathetic trunks
The divisions of the mediastinum
Superior Inferior - Middle - Anterior - Posterior
What divides the superior and inferior mediastinum?
by an imaginary plane passing from:
- anteriorly: sternal angle - posteriorly: T4 vertebra lower border
It consists of the pericardium and heart
middle mediastinum
a space between the pericardium and the sternum
anterior mediastinum
lies between the pericardium and the vertebral column.
posterior mediastinum
What does potential space contain and what for?
minimal fluid presence to prevent too much friction
What are the borders of superior mediastinum?
superiorly - oblique plane of the first rib
inferiorly - imaginary line running from the sternal angle to the intervertebral disk between T4 and T5 vertebra
What contains the superior mediastinum?
(10) superior vena cava (SVC), and brachiocephalic veins arch of the aorta thoracic duct trachea esophagus vagus nerve left recurrent laryngeal nerve phrenic nerve thymus
Where is the site at which immature lymphocytes develop into T lymphocytes and secretes thymic hormones?
Thymus
What does secretion of thymic hormones cause?
cause T lymphocytes to gain immunocompetence
Where is thymus prominent in children?
at lower mediastinum (looking like a boat/ sail sign)
Lies anterior to the pericardium and posterior to the sternum and the transverse thoracic muscles
Anterior Mediastinum
What does the Anterior Mediastinum contain?
(4) remnants of the thymus gland lymph nodes fat connective tissue
Lies between the right and left pleural cavities
Middle Mediastinum
What does Middle Mediastinum contain?
(6) heart pericardium phrenic nerves roots of the great vessels (aorta, pulmonary arteries and veins, and vena cavae) arch of the azygous vein main bronchi.
Lies posterior to the pericardium between the mediastinal pleurae
Posterior Mediastinum
What contains the Posterior Mediastinum?
(8) esophagus thoracic aorta azygos and hemiazygos veins thoracic duct vagus nerves sympathetic trunk splanchnic nerves
Where is the recurrent branch of left laryngeal nerve?
arch on the arch of the aorta
Where is the recurrent branch of right laryngeal nerve?
arch through brachiocephalic artery
What are the boundaries of the inferior mediastinum?
Anterior: body of sternum
Posterior: vertebra
Inferior: diaphragm
Begins at the inferior border of the cricoid cartilage as a continuation of the larynx and ends by bifurcating into the right and left main stem bronchi at the level of the sternal angle
Trachea
At what level is the cricoid cartilage?
C6
At what level is the hyoid bone?
C2
At what level is the thyroid cartilage?
C4
Trachea is approximately 12 cm in length and what does it have that open posteriorly toward the esophagus and prevent the trachea from collapsing?
16 to 20 incomplete hyaline cartilaginous rings
It may be compressed by an aortic arch aneurysm, a goiter, or thyroid tumors, causing dyspnea
Trachea
What does the trachea have which is a downward and backward projection of the last tracheal cartilage, which lies at the level of the sternal angle and forms a keel-like ridge separating the openings of the right and left main bronchi?
carina
It is the internal landmark where trachea bifurcates into right and left mainstem bronchi
carina
What surgical procedure requires carina to be known?
Bronchoscopy
Carina may be distorted, widened posteriorly, and immobile in the presence of a?
bronchogenic carcinoma
What is one of the most sensitive areas of the tracheobronchial tree and is associated with the cough reflex?
The mucous membrane over the carina
Where is the direct origin of inferior thyroid artery?
thyrocervical trunk
What supplies blood in the upper trachea?
inferior thyroid artery
What supplies blood in the lower part of trachea?
Branches of the bronchial artery
Where is the venous drainage of trachea?
Inferior thyroid venous plexus
It is the shorter, wider and more vertical bronchus.
Right main (Primary) Bronchus
Runs under the arch of the azygos vein and divides into 3 lobar or secondary bronchi and finally into 10 segmental bronchi
Right main (Primary) Bronchus
The right superior lobar (secondary) bronchus is known as?
eparterial (above the artery) bronchus
All other types of secondary bronchus are?
hyparterial (below artery) bronchi.
What are the 3 lobar bronchus of right main bronchi?
superior, middle, and inferior
Runs inferolaterally inferior to the arch of the aorta, crosses anterior to the esophagus and thoracic aorta, and divides into 2 lobar or secondary bronchi, the upper and lower, and finally into 8 to 10 segmental bronchi.
Left Main (Primary) Bronchus
Which main bronchi are more foreign bodies likely to enter through the trachea?
Right main (Primary) Bronchus
Longer, narrower, and more angulated bronchus
Left Main (Primary) Bronchus
What does the left main bronchus crosses superiorly on its proximal and distal parts respectively?
Proximal: arch of the aorta
Distal: left pulmonary artery
Chronic obstruction of airflow through airways and lungs
Chronic obstructive pulmonary disease (COPD)
inflammation of airways, resulting to excessive mucus production that plugs up airways
Chronic bronchitis
accumulation of air in the terminal bronchioles and alveolar sacs
Emphysema
chronic inflammation of bronchi that causes swelling and narrowing of airways
Asthma
general term for chronic dilation of bronchi and bronchioles
Bronchiectasis
A thin serous membrane that consists of a parietal pleura and a visceral pleura
Pleura
Lines the inner surface of the thoracic wall and the mediastinum and has costal, diaphragmatic, mediastinal, and cervical parts.
Parietal Pleura
The dome of the pleura, projecting into the neck above the neck of the first rib
cervical pleura (cupula)
What reinforced the cupula?
Sibson fascia/ suprapleural membrane
What innervates parietal pleura?
intercostal nerves
phrenic nerves
What supplies the parietal pleura?
branches of the internal thoracic (1)
superior (2), phrenic (3), posterior intercostal artery (4), and superior intercostal artery (5)
What do the veins of parietal pleura join?
systemic veins
What does the parietal pleura form, which is a two-layered vertical fold of mediastinal pleura, which extends along the mediastinal surface of each lung from the hilus to the base and ends in a free falciform border?
pulmonary ligament
Intimately invests the lungs and dips into all of the fissures
Visceral pleura (Pulmonary Pleura)
What supplies visceral pleura?
bronchial arteries
What drains the venous blood of visceral pleura?
pulmonary veins
Which pleura is sensitive to pain and which is sensitive to stretch?
pain: parietal pleura
stretch: visceral pleura
It contains vasomotor fibers and sensory endings of vagal origin, which may be involved in respiratory reflexes
Visceral pleura (Pulmonary Pleura)
lower border of lung midclavicular lines, midaxillary lines, and sides of vertebral column (paravertebral line) respectively?
midclavicular: 6th rib
midaxillary: 8th rib
paravertebral: 10th rib
lower border of pleura midclavicular lines, midaxillary lines, and sides of vertebral column (paravertebral line) respectively?
midclavicular: 8th rib
midaxillary: 10th rib
paravertebral: 12th rib
• A potential space between the parietal and visceral pleurae
• Represents a closed sac with no communication between right and left parts
Contains a film of fluid that lubricates the surface of the pleurae and facilitates the movement of the lungs
Pleural Cavity
- Pleural recesses formed by the reflection of the costal and diaphragmatic pleurae
* Can accumulate fluid when in the erect position
* Allow the lungs to be pulled down and expanded during inspiration
Costodiaphragmatic Recesses
Are part of the pleural cavity where the costal and mediastinal pleurae meet
Costomediastinal Recesses
accumulation of air in the pleural cavity, the lung collapses because the negative pressure necessary to keep the lung expanded has been eliminated.
Pneumothorax
Can be treated by draining the pleural air collection by simple aspiration using an intravenous catheter or chest tube thoracostomy (needling)
Pneumothorax
abnormal accumulation of fluid in the pleural cavity
Pleural effusion
Usually seen in car accidents, blunt trauma to the thorax
Pneumothorax
clear watery fluid
Transudate
cloudy viscous fluid
Exudate
How is pleural effusion treated?
thoracentesis
A surgical puncture of the thoracic wall into the pleural cavity for aspiration of fluid
Thoracentesis (pleuracentesis or pleural tap)
Where are the ideal sites in thoracentesis?
7th, 8th, or 9th intercostal space, inserted above the superior margin of a rib
What sites are avoided during thoracentesis?
lung, spleen, liver, diaphragm
intercostal neurovascular bundle
Essential organs of respiration and are attached to the heart and trachea by their roots and the pulmonary ligaments
Lungs
What nourishes and drains nonrespiratory tissues respectively?
nourished by: bronchial arteries
drained by: bronchial veins for the larger subdivisions of the bronchi
pulmonary veins for the smaller subdivisions of the bronchial tree
Parasympathetic indication of lungs
bronchoconstrictor and secretomotor
Sympathetic indication of lungs
bronchodilator and vasoconstrictor
Have some sensory endings of vagal origin, which are stimulated by the stretching of the lung during inspiration and are concerned in the reflex control of respiration
Lungs
Larger and heavier but is shorter and wider
Right lung
Why is the right lung shorter and wider?
because of the liver presence in the diaphragm
Right lung has 3 lobes which are divide by?
oblique and horizontal (accessory) fissures
usually begins at the head of the fifth rib and follows roughly the line of the sixth rib.
oblique fissure
runs from the oblique fissure in the midaxillary line at the sixth rib level and extends forward to the fourth costal cartilage level
horizontal fissure
How many is the bronchial artery of right lung?
1
Has 3 lobar (secondary) bronchi and 10 segmental (tertiary) bronchi
Right lung
Has grooves for various structures (e.g., SVC, arch of azygos vein, esophagus)
Right lung
What divides the left lung?
an oblique fissure
Where is an oblique fissure usually more vertical?
Left lung
a tongue-shaped portion of the upper lobe that corresponds to the middle lobe of the right lung
lingula
Contains a cardiac impression, a cardiac notch (a deep indention of the anterior border of the superior lobe of the left lung), and grooves for various structures (e.g., aortic arch, descending aorta, left subclavian artery)
Left lung
Has 2 lobar (secondary) bronchi and 8 to 10 segmental bronchi
Left lung
The anatomic, functional, and surgical unit (subdivision) of the lungs
Bronchopulmonary Segment
What consists the Bronchopulmonary Segment?
segmental (tertiary or lobular) bronchus
segmental branch of the pulmonary artery
segment of the lung tissue
Refers to the portion of the lungs supplied by each segmental bronchus and segmental artery. The pulmonary veins are said to be intersegmental.
Bronchopulmonary Segment
What drains the Bronchopulmonary Segment?
intersegmental part of the pulmonary vein
What does the intersegmental pulmonary veins form which allows the removal of a bronchopulmonary segment without seriously disrupting the surrounding lung tissue and major blood vessels?
surgical landmarks
What are the main bronchopulmonary segments of the right lung?
Superior lobe: apical, posterior, anterior
Middle lobe: lateral, medial
Inferior Lobe: superior (apical), medial basal, anterior basal, lateral basal, posterior basal
What are the main bronchopulmonary segments of the left lung?
Superior: apical, posterior, anterior, superior lingular, inferior lingular
Inferior lobe: superior (apical), medial basal, anterior basal, lateral basal, posterior basal
Includes the nasal cavity, nasopharynx, larynx, trachea, bronchi, bronchioles (possess no cartilage), and terminal bronchioles
Conducting Portion
Includes the respiratory bronchioles, alveolar ducts, atria, and alveolar sacs.
respiratory portion
Vital exchange of oxygen and carbon dioxide that occurs in the lungs.
Respiration
What does the air-blood barrier contain?
alveolar type I cells,
basal lamina, and
capillary endothelial cells
What does The alveolar type II cells secrete?
Surfactant
When is the surfactant completed?
34 weeks
What does the surfactant do?
Increases surface tension of lungs
Occurs when the ribs and sternum (or thoracic cage) are elevated by the following muscles: diaphragm; external, internal (interchondral part), and innermost intercostal; sternocleidomastoid; levator costarum; serratus anterior; scalenius; pectoralis major and minor; and serratus posterior superior muscles.
Inspiration
Pulls the dome inferiorly into the abdomen, thereby increasing the vertical diameter of the thorax
Contraction of the Diaphragm
Reduces the intrapulmonary pressure (creates a negative pressure), thus allowing air to rush into the lungs passively because of atmospheric pressure
Enlargement of the Pleural Cavities and Lungs
Involves contraction off the intercostal muscles and elevation of ribs (superolateral movement), with the sternum moving anteriorly like a bucket handle. (When the handle is raised, the convexity moves laterally)
Forced Inspiration
Results in increased transverse and anteroposterior diameters of the thoracic cavity. The abdominal volume is decreased with an increased abdominal pressure
Forced Inspiration
What is the primary muscle of inspiration and its innervation?
Diaphragm
Innervated by C2-C4
Involves the following muscles: muscles of the anterior abdominal wall, internal intercostal (costal part) muscles, and serratus posterior inferior muscles
Expiration
Involves relaxation of the diaphragm, the internal intercostal muscles (costal part), and other muscles; decrease in thoracic volume; and increase in the intrathoracic pressure.
Overall Process
What happens to the abdominal pressure and position of ribs in expiration?
abdominal pressure - decreased
ribs - depressed
Produces a subatmospheric pressure in the pleural cavities. Thus, much of the air is expelled.
Elastic Recoil of the Lungs
A passive process caused by the elastic recoil of the lungs
Quiet expiration
It results from contraction of the diaphragm
quiet inspiration
Requires contraction of the anterior abdominal muscles and the internal intercostals (costal part)
Forced Expiration
What is the primary muscle of expiration?
No primary muscle, because it is a passive process
Drain the bronchial tree, pulmonary vessels, and connective tissue septa
Lymphatic Vessels of the Lungs
Direction of drainage in the bronchiole and bronchi
bronchopulmonary nodes tracheobronchial nodes tracheal nodes bronchomediastinal nodes thoracic duct on the left and right lymphatic duct on the right
Extends upward from the conus arteriosus of the right ventricle of the heart and carries poorly oxygenated blood to the lungs for oxygenation
Pulmonary Trunk
Passes superiorly and posteriorly from the front of the ascending aorta to its left side for approximately 5 cm and bifurcates into the right and left pulmonary arteries within the concavity of the aortic arch at the level of the sternal angle
Pulmonary Trunk
Has much lower blood pressure than that in the aorta and is contained within the fibrous pericardium
Pulmonary Trunk
Serves as landmark to distinguish eparterial and hyparterial bronchi
Pulmonary Trunk
Carries deoxygenated blood to the left lung, is shorter and narrower than the right pulmonary artery, and arches over the left primary bronchus
Left Pulmonary Artery
Connected to the arch of the aorta by the fibrous remains of the ductus arteriosus called?
ligamentum arteriosum
Runs horizontally toward the hilus of the right lung under the arch of the aorta behind the ascending aorta and SVC and anterior to the right bronchus
Right Pulmonary Artery
- Carry oxygenated blood from the respiratory part (alveoli) of the lung
- Intersegmental in drainage
- only four veins enter the left atrium
Pulmonary Veins
Arise from the thoracic aorta; usually there is one artery for the right lung and two for the left lung
Bronchial Arteries
Supply oxygenated blood to the nonrespiratory conducting tissues of the lungs and the visceral pleura.
Bronchial Arteries
Receive blood from the bronchi and empty into the azygos vein on the right and in accessory hemiazygos vein or the superior intercostal vein on the left
Bronchial Veins
May receive twigs (small vessels) from the tracheobronchial lymph nodes
Bronchial Veins
An obstruction of the pulmonary artery or one of its branches by an embolus (air, blood clot, fat, tumor cells, or other foreign material)
Pulmonary embolism (pulmonary thromboembolism)
Bed-ridden people and people with varicose veins are at risk to this
Pulmonary embolism (pulmonary thromboembolism)
Receives afferent and efferent (parasympathetic preganglionic) fibers from the vagus nerve, joined by branches (sympathetic postganglionic fibers) from the sympathetic trunk and cardiac plexuses
Pulmonary Plexus
What are the two divisions of Pulmonary Plexus?
anterior pulmonary plexus
posterior pulmonary plexus
Arises from the third through fifth cervical nerves (C3-C5) and lies in front of the anterior scalene muscle
Phrenic Nerve
It supplies the central diaphragm, mediastinal pleura, and pericadium.
Phrenic Nerve
What part of diaphragm is supplied by the 6th to 12tg intercostal nerves
Peripheral diaphragm
The conducting (airway) system through the terminal bronchioles develops. Respiration is not possible
Glandular Period (Prenatal Weeks 5 to 17)
Luminal diameter of the conducting system increases, and respiratory bronchioles, alveolar ducts, and terminal sacs begin to appear. Premature fetuses born before week 20 rarely survive
Canalicular Period (Prenatal Weeks 13 to 25)
More terminal sacs form, and alveolar type I cells and surfactant-producing alveolar type II cells develop. Respiration is possible, and premature infants can survive with intensive care
Terminal Sac Period (Prenatal Weeks 24 to Birth)
Respiratory bronchioles, terminal sacs, alveolar ducts, and alveoli increase in number
Alveolar Period (Late Fetal Stage to 8 Years)