Med-Surg: Cancer Treatment Options Flashcards
Tumor Reduction
can be done through topical procedures (cryosurgery, laser therapy, ablation) or by destruction of the main arteries that provide blood flow to the tumor (artery embolization)
Tumor Excision
can be open or endoscopic (curettage and electrodissection for skin cancer)
- the tumor and tissue immediately surrounding it (tumor margin) are removed; Goal: all of the outermost tissue that was removed does not contain cancer cells (a negative margin)
- surgery can be done for biopsy (diagnosis and staging), or relief (palliative)
Lymph Node Dissection
or sentinel lymph node biopsy
-done to determine if the cancer has spread or there is added risk of spread
Chemotherapy
involves administration of systemic or local cytotoxic medications that damage cells DNA or destroy rapidly dividing cells
Chemotherapy Route
- given topical (for skin lesions), oral, parenteral, IV, intra-arterial, intraventricular (ventricles of the brain), intracavitary which includes intraperitoneal (abdominal cavity), intravesicular (into bladder), intrapleural (into pleural space), and intrathecal (into spinal cavity)
- specialized training for administration
- oral anticancer medications are just as toxic to the client taking the medication and the nurse handling the medication as are standard chemotherapy medications
- oral medications should not be crushed, split, broken, or chewed
Chemotherapy: Catheters
a central catheter is usually placed for IV chemotherapy administration or blood testing
- some medications can cause damage to the skin and muscle tissue if they leak outside a vein (vesicants)
- a port is implanted for long-term basis
Chemotherapy: Nursing Actions
- instruct client on proper use of vascular access devices
- instruct family to dispense oral medications directly into a cup and not to touch pills or liquids with the hands
- closely monitor IV infusions and provide immediate treatment or extravasation; identify the antidote for medication client is receiving
Chemotherapy Complications
- immunosuppression/neutropenia
- nausea, vomiting, anorexia
- alopecia
- hypersensitivity
- oral mucositis
- anemia/thrombocytopenia
- peripheral neuropathy
- cognitive impairment
Chemotherapy Complications: Immunosuppression/Neutropenia
due to bone marrow suppression by cytotoxic medications
- pts with neutropenia might not develop a high fever or have purulent drainage even when infection present
- risk of serious infection increases as the absolute neutrophil count (ANC) falls. An ANC less than 1,000/mm3 = weak immune system and need to initiate neutropenic precautions
> Nursing:
- monitor temperature, WBC count, and ANC
- report fever greater than 100 Degrees F to provider
- monitor skin and mucous membranes for infection (breakdown, fissures, and abscess)
- obtain cultures prior to initiating prescribed antimicrobial therapy
> Client Education:
- avoid crowds while undergoing chemotherapy
- take temperature daily. report elevated temp
- avoid food sources that could contain bacteria (fresh fruits and vegetables, undercooked meat, fish, and eggs, pepper, and paprika)
- avoid yard work, gardening, or changing a pet’s litter box; wear disposable gloves when working with house plants or outdoor gardening
- discard liquid beverages that have been sitting at room temperature for longer than 1 hr
- wash all dishes in hot, soapy water or a dishwasher
- wash glasses and cups after each use
- wash toothbrush daily in the dishwasher or rinse in a bleach solution
- do not share toiletry or personal hygiene items with others
- report manifestations of bacterial or viral infections immediately to the provider
Neutropenic Precautions
- assign a private room; have client remain in the room unless they need to leave for a diagnostic procedure or therapy; place mask on client during transport
- protect from sources of infection (live plants, stagnant water, contaminated equipment)
- perform hand hygiene
- restrict visitors who are ill
- avoid invasive procedures that could cause a break in tissue (rectal temperatures, injections, indwelling urinary catheters) unless necessary
- keep dedicated equipment (blood pressure machine, thermometer, stethoscope) in clients room
- administer colony-stimulating factors (filgrastim) to facilitate WBC production
Filgrastim
facilitate WBC production
filgraSTIM
Chemotherapy Complications: Nausea, vomiting, anorexia
many medications used for chemotherapy are emetogenic (induce vomiting) or cause anorexia and an altered taste in the mouth
> Nursing Actions:
- ensure antiemetics are given before chemotherapy and repeated based on the response and duration of CINV
- administer antiemetic medications several days after each treatment, even when CINV appears to be controlled
- remove vomiting cues such as odor and emesis basins
- nonpharmacological methods to reduce nausea (visual imagery, relaxation, acupuncture, distraction)
- calorie counts to determine intake; provide liquid nutritional supplements as needed; add protein powders to food or tube feedings
- administer megestrol to increase appetite if prescribed
- assess for dehydration and fluid or electrolyte imbalance
- perform mouth care prior to serving meals to enhance appetite
> Client Education
- some antiemetics can provide prophylactic treatment if given before meals
- eat several small meals a day if better tolerated
- eating low-fat dry foods (crackers, toast) and avoiding drinking liquids during meals can prevent nausea
- select foods that are served cold and do not require cooking; cooking food can emit odors that stimulate nausea
- encourage consumption of high-protein, high-calorie, nutrient-dense foods
- avoid low or empty calorie foods; use meal supplements as needed
- use plastic eating utensils, suck on hard candy, and avoid consuming red meat to prevent or reduce the sensation of metallic taste
- create food diary to identify items that can trigger nausea
Chemotherapy Complications: Alopecia
hair loss
- temporary
- can vary, can occur anywhere on the body
> Nursing Actions:
- discuss effect on self-image
- discuss options (hats, turbans, wigs) to deal with hair loss
- reinforce that hair should return about 1 month after chemotherapy is d/c; new hair can differ from original hair in color, texture, and thickness
> Client education
- hair loss occurs 7 to 10 days after treatment begins
- avoid use of damaging hair care measures (electric rollers, curling irons, hair dye, permanent waves)
- a soft hair brush or wide-tooth comb for grooming
- consider cutting the hair short before treatment to decrease weight on hair follicle
- consider collaborating with hairdresser to assist with wig selection; wearing a wig before therapy begins can reduce appearance changes
- after hair loss, protect scalp from sun exposure and use a diaper rash ointment/cream for itching
- use head coverings to reduce body heat loss and protect skin while wearing helmets, headphones, headsets, or wigs
Chemotherapy Complications: Hypersensitivity
reactions can occur as early as 1 hr following infusion but possible after several doses
> Nursing:
- stop medication immediately if manifestations of hypersensitivity occurs
- assist with administration of emergency treatment
> client education
- watch for and report indications of hypersensitivity reaction immediately
- if hypersensitivity occurs, desensitization to the medication might be required so that the client can continue to receive the treatment most appropriate to combat the cancer
Chemotherapy Complications: Oral mucositis
inflammation in the mucous lining of the upper GI tract from the mouth to the stomach
> Nursing:
- examine clients mouth several times a day, and inquire about presence of oral lesions
- document the location and size of lesions; for new lesions obtain a specimen for culture and report to provider
- avoid using glycerin-based mouthwashes or swabs; nonalcoholic, anesthetic mouthwashes recommended
- administer topical anesthetic prior to meals
- discourage consumption of salty, acidic, or spicy foods
- offer oral hygiene after and before meals
- use lubricating or moisturizing agents to counteract dry mouth
> Client Education:
- rinse mouth with a solution of 0.9% sodium chloride, room-temperature tap water, or salt and soda water
- gentle flossing and brushing using a soft-bristled toothbrush or foam swabs to avoid traumatizing the oral mucosa
- rinse mouth before and after meals
- avoid mouthwash that contains alcohol or other irritants
- take medications to control infection (nystatin suspension, acyclovir)
- follow recommendations regarding use of coating agents, topical analgesics, topical anesthetics, or oral parenteral analgesics
- choose soft, bland foods and supplements that are high in calories (mashed potatoes, scrambled eggs, cooked cereal, milk shakes, ice cream, frozen yogurt, bananas, and breakfast mixes)
- avoid spicy, salty, acidic, rough, or hard food
- avoid drinking alcohol and the use of tobacco
- drink at least 2 L of water per day unless there is a fluid restriction