Lymphatic System Wk12 Flashcards

1
Q

What is the role of the lymphatic system?

A

To return Fluid from intersistial space to the arterial system

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2
Q

What are the lymphatics responsible for?

A

Returning proteins and plasma and fluids back to venous drainage

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3
Q

Functions of lymphatic system include

A

Fluid homeostasis, filter contents of extracellular tissue space, cell populations of blood, lymphocytes & antibodies production, fat absorption from the gut

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4
Q

Fat absorption from the gut

A
  • lacteals contain chyle and drain into thoracic duct
    Here lymph thicker & contains more protein
    and fat (milky appearance)
    This means lymph from gut goes directly to
    venous circulation - not through liver first
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5
Q

Name the components of the lymphatic system

A

Lymphatic vessels (channels)
* lymph nodes (filters)
* other masses of lymphoid tissue
* spleen, thymus, walls of gut (e.g.,
appendix) & bone marrow

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6
Q

Describe how lymph travels from interstitial space to
venous drainage

A

Through lymphatic channels and end by delivering fluids into veins

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7
Q

Lymphatic channels begin as

A

dilated, bulb-like blind swellings in tissue spaces

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8
Q

Lymphatic channels form networks in tissue

A

spaces that form trunks that pass through lymph nodes

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9
Q

Dermis has the high

A

density of lymphatics

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10
Q

Lymph nodes act as

A

filters = - collections of lymphocytes bound by connective tissue

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11
Q

Movement of lymph is based on

A

pressure changes in the tissue - contraction of surrounding muscles that help

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12
Q

Intrathoracic pressure sucks ___

A

Negative intrathoracic
pressure during inspiration sucks lymph up
thoracic duct

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13
Q

Where does the lymph drain into?

A

Lymph vessels from lower trunk empty to thoracic duct - SVC (b/w left int jugular vein & left subclavian vein)

Lymph from right side of the neck, right arm, and parts of the right thorax enter the right lymphatic duct & much
smaller than thoracic duct

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14
Q

What are the main lymph nodes?

A

Cervical, axillary, deep, inguinal, femoral, pericranial ring, tracheal nodes

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15
Q

What sites are palpable?

A

Axilla, groin, femoral region, neck

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16
Q

Which sites are not palpable?

A

Trachea and bronchi in thorax
Aorta
Branches in abdomen

17
Q

Name lymphoid tissues in the body

A

Primary: Thymus & Bone marrow
Secondary: Lymph nodes; Tonsils (oral cavity +
nasopharynx); Spleen;
Peyer’s patches (GIT);
Vermiform Appendix
(GIT); Mucosa Associated
Lymphoid Tissue

18
Q

Function of glymphatic system is

A
  • Waste clearance (esp sleep)
  • Distribution of nutrients incl glucose throughout the brain
19
Q

When our glymphatic system is not working,

A

Neurodegenerative diseases where accumulation of
pathological proteins and plaques is a feature

20
Q

In Alzheimer’s disease, we see

A

clearance of Ab plaques

21
Q

What is the

A

Periarterial CSF inflow → interstitial fluid (brain parenchyma) mmt
into astrocyte facilitated by aquaporin-4 → perivenous space + cranial and spinal nerves. Transported out of CNS by meningeal
lymphatic vessels