Lymphatic system Flashcards

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1
Q

What four things does the lymphatic system consist of?

A

-Lymph
-Lymphatic vessels
-Lymphatic tissue
-red bone marrow

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2
Q

What are the functions of the lymphatic system?

A

-drainage of interstitial fluid
-transporting dietary lipids and lipid soluble vitamins (A,D,E,K)
-facilitation of the immune response

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3
Q

How does lymph form?

A

structural relationship between cappilary bed of the blood vascular system and lymphatic cappilaries.

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4
Q

Describe hydrostatic pressure

A

the pushing force exerted by a fluid
~30-10 mmHg between arterial and venous end

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5
Q

Describe interstital fluid pressure

A

slightly negative -3mmHg which contributes to the outward pull of fluid from the cappilaries

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6
Q

Describe collodial osmotic pressure

A

the pulling force created by blood proteins that are too large to pass through the pores of the membrane

~28mmHg in the cappilaries

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7
Q

Describe interstital osmotic pressure

A

is ~8mmHg
-created by a small number of plasma proteins that have leaked into the extracellular tissue space

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8
Q

How is blood plasma converted into interstital fluid?

A

blood hydrostatic pressure pushes blood plasma out of the blood cappilaries to bathe surrrounding tissue.

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9
Q

Decribe the role of the protein albumin in the formation of lymph

A

-albumin is too large to leave the cappilaries and creates an osmotic pressure inside the cappilaries

-the blood osmotic pressure pulls interstital fluid back into blood cappillaries

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10
Q

How does drainage of unreturned interstital fluid occur?

A

-lymphatic cappilaries and lymph vessels

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11
Q

how does fluid enter the lymph cappilary?

A

-one way minivalves
-once inside it is known as lymph

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12
Q

Dsecribe the process involved in the drainage of lymph

A

-lymph cappilaries join to form lymph vessels

-lymph vessels are similar to veins-they have certain internal structures to ensure lymph flows one way

-lymph vessels drain into one of two ducts which return lymph to blood

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13
Q

name the two lymph ducts

A

-right lymphatic duct
-left thoracic duct

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14
Q

Describe the fuction of the right lymphatic duct

A

-drains upper right side of the body and right arm

-returns lymph to the right subclavian vein

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15
Q

Describe the function of the left thoracic duct

A

-drains the rest of the body
-the left thoracic duct begins with the cisterna chyli amd returns lymph to the left subclavian vein

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16
Q

describe how lymph drains into the cisterna chyli

A

-lymph cappilaries in small intestine-lacteals
-lacteals carry fat laden lymph-chyle
-lacteals join together to form vessels
-vessels containing fat laden lymph drain into cisterna chyli

17
Q

Describe the links between the CV and lymphatic system

A

-plasma forms interstital fluid
-interstital fluid returned to the plasma
-fluid that is not returned to the plasma enters the lymph cappilaries to form lymph
-lymph is returned to the CV

18
Q

What is oedema?

A

palpable swelling produced by an increase in interstital fluid volume

19
Q

What factors influence oedema?

A

-increased cappilary filtration pressure
-decreased cappilary colloidal osmotic pressure
-increased cappilary permeability
-obstruction to lymph flow-lympoedema

20
Q

Where can you find lymph nodes?

A

-pharyngeal region/tonsils
-thymus
-spleen
-Peyers patch in intestine
-appendix

21
Q

What pathway is lymph recieved?

A

afferent (going towards vessels)

22
Q

What pathway is lymph drained?

A

efferent (going away from vessels)

23
Q

Describe the structure of lymph nodes

A

-surrounded by connective tissue capsules

-trabeculae project inwards from capsules forming compartments

-each compartment is made up of reticular cells
between recticular cells are lymphocytes

24
Q

What is the function of recticular cells?

A

phagocytise unwanted substances

25
Q

What do lymphocytes produce?

A

antibodies

26
Q

Name some structures in the recticular cells of lobule

A

-macrophage
-reticular cells on reticular fibres
-lymphocytes
-medullary sinus
-reticular fibers

27
Q

Describe the peyer’s patches

A

-direction of absorption and possible entry of microorganisms

-nodules also found in mucosa of other tubular structures in respiratory, urinary and reproductive systems

28
Q

What does MALT stand for?

A

Mucosa
Associated
Lymphoid
Tissue

29
Q

Name the five types of tonsils

A

2x palatine (either side of the oral cavity)

2x lingual (at the base of the tongue

1x Pharyngeal or adenoid
(on the posterior wall of the nasopharynx)

30
Q

What is the structure if the thymus gland?

A

-found in the mediastinum above the heart
-surrounded by a connective tissue capsule with inward projecting trabeculae

31
Q

What is the function of the thymus gland?

A

-produce thymic factor
-thymic factor is important in setting up the immune system and the formation of T lymphocytes

32
Q

Describe age involution of the thymus gland

A

thymus is largest in childhood
-after childhood the thymus decreases in size

33
Q

where is the spleen located?

A

left side of abdominal cavity below the diaphragm

34
Q

What is the spleen comprised of?

A

recticular cells-lymphatic tissue
red pulp
white pulp

35
Q

What is the function of red pulp?

A

removes worn out platelets and RBCs, stores platelets and produces RBCs in the foetus

36
Q

What is the function of white pulp?

A

Carries immune funtion and removes blood borne pathogens