Lesson 1B (Part 1) Flashcards
Hepatitis
Inflammation of the liver
How many distinct types of hepatitis is there?
6
- A –> E/G
Serosuvey
Study of blood serum to find antibodies when exposed to hepatitis
What could happen if hepatitis is not treated?
It can be fatal
What can hepatitis lead to? (3)
- Portal hypertension
- Cirrhosis
- Hepatocellular carcinoma
- HCC
How does Hep A spread?
Fecal-oral route
Who does Hep A affect?
The young
- put lots of stuff in their mouths
What kind of infection do you get from Hep A?
Acute
How is Hep B transmitted?
Parentally
- not oral
How can Hep B spread? (3)
- Blood transfusions
- Needle punctures
- Sexual contact and at birth
Where is Hep B common? (3)
- Asia
- Africa
- Greenland
Where is Hep C common? (2)
- Italy
2. Mediterranean
How does Hep C spread?
Blood
- eg. sharing needles
What is Hep D dependent on for infectivity?
Hep B
Where is Hep D common?
- Asia
- Africa
- Greenland
- same as Hep B
Who is most likely to get Hep D?
IV drug users
What are symptoms of viral hepatitis? (7)
- Fatigue
- Headache
- Anorexia
- Fever
- Abdominal pain
- Nausea
- Vomiting
What is a sign of hepatitis?
Jaundice
What does acute hepatitis imply?
Recovery within 4 months
What is the common appearance of acute hepatitis? (3)
- Hypoechoic
- Echogenic periportal walls
- Starry night sky
What does chronic hepatitis imply?
Abnormalities persisting beyond 6 months
What is the common appearance of chronic hepatitis? (2)
- Hepatomegaly
2. Thickening of the GB wall
What can be harmful to the liver? (3)
- Alcohol
- Prescription medications
- Poor diet
What are 4 disorders of metabolism?
- Steatosis
- fatty liver - Glycogen storage disease
- neonatal (not from lifestyle) - Cirrhosis
- chronic liver disease - NASH
- non-alcoholic steatohepatitis
Can steatosis be reversible?
Yes
- this is done by correcting the situation
What is the most common cause of steatosis?
Obesity
Steatosis
Fatty liver
- triglycerides (fat) in the hepatocytes
What are other possible causes for steatosis? (10)
- Excessive alcohol
- stimulates lipolysis - Severe hepatitis
- Hyperlipidemia
- cholesterol - Diabetes
- Excess corticosteroids
- Pregnancy
- Hyperalimentation
- Obesity bypass surgery
- Cystic fibrosis
- Toxins
What is steatosis a significant precursor for?
Chronic diseases
What are the deposits of steatosis like? (2)
- Focal
2. Diffuse