lecture 3 part 2 Flashcards

1
Q

non covalent bonds`

A

keep atoms close together without sharing electrons

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2
Q

what are biologically important non covalent bonds

A

-hydrogen bonds
-ionic bonds
-van der waals forces (occur due to hydrophobic interactions)

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3
Q

are non covalent bonds individually weaker than covalent bonds

A

yes

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4
Q

what are hydorgen bonds and ionic bonds due to

A

due to the attraction of opposite charges

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5
Q

where do hydorgen bonds exists

A

exist between two atoms with opposite partial charges
-water is not required but it frequently forms hydrogen bonds)
-the partial charge is on a hydrogen atom
-partial negative charge is usually on a N or O atom

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6
Q

what do hydrogen bonds give water

A

its special properties important for life
-surface tension (cohesive forces)

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7
Q

can water form hydrogen bonds with other polar molecules

A

yes
-glucose
-ammonia

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8
Q

hydroxyl group

A

OH

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9
Q

Hydrogen bonds are a type of _____ _______ bond and are due to the attractions of _______ charges (no sharing electrons)

A

non covalent; opposite

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10
Q

ionic bonds

A

hold together two ions with opposite charges (number of protons doe snot equal number of electrons)

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11
Q

ionic bonds in different environments

A

they are strong in dry environments and weak in aqueous environemnts
-in many aq solutions ionic bonds dissocoaute (why salt dissolves in water)

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12
Q

water forms ________ _____ around ions

A

hydration shell
-several water moleqs surround the ion
-opp charges on water oriented towards the ion

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13
Q

uncharged polar molecules and ions interact well with ______ and are called ________ molecules

A

water; hydrophillic

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14
Q

ions often ______ in water but they dont form __ ______ with water

A

dissolve; Hydrogen bonds

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15
Q

do no polar molecules interact well with water and what are they called

A

no and they are called hydrophobic molecules

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16
Q

what do non polar molecules do in water

A

they group together in water because water molecules for H bonds with on another

17
Q

hydrophobic interactions

A

association of non polar molecules (or non polar regions w/in a molecule)
-lessens interactions with water and other polar moleqs (or polar regions w/in moleq)

18
Q

van der waals forces

A

weak attractive forces between adjacent moleqs due to transient fluctuations in electrical charges

19
Q

what type of force stabilizes hydrophobic interactions

A

wan der waals forces

20
Q

do avn der waals forces initiate hydrophobic interactions

A

no hydrophobic interactions do

21
Q

what are critical for the 3D structure of many macromolecules

A

non covalent bonding

22
Q

what type of bond stabilizes the double stranded DNA struvture

A

hydorgen bonds

23
Q

non covalent bonds are necessary for what

A

proteins to be in their correct 3D shape (so they can function properly)

24
Q

structure determines what

25
what can stabilize the loop structure in protein
non covalent bond
26
what are important for intermolecular interactions
non polar covalent bonds
27
intermolecular interactions is between ____ moleqs
2
28
exampels of intermolecular interactions
-hormone binding to receptor -body binding to pathogen -enzyme binding to substance -transcription factor binding to DNA to regulate gene expression
29
what are some non covalent bonds important points
-individually much weaker than covalent bonds (because they don't share e-) -collectively exhibit strength in proportion to their numbers -changes in environment conditions can cause them to break and molecules to denature or dissociate
30
what can disrupt non covalent bond
higher than optimum temperatures
31
what happens to non covalent bonds in higher than optimum temps
cause the molecules to denature (unfold) or dissociate -proteins -nucleic acids -lipids with hydrophobic tails
32
what can disrupt hydorgen and ionic bonding
salt concentration and pH