lecture 14 part 3 Flashcards
what happens to the pyruvate from glycolysis in aerboci respiration
pyruvate enters a mitochondria and is conerted to acetyle CoA
-in this reaction pyruvate is oxidized
-occurs in mitochondria of eukaryotic cells and cytosol of prokaryotes
oxidized means
loses e-
in euaryotes 3 of the 4 steos of aerobic respiration occurs in the _____
mitocondria
enzymes for pyruvate oxidation and citric acid cycle are in
the matric
1st pyruvate must get into the _____
matrix
what helps the pyruvate to pass through outer membrane
large protein that makes it easy for mole to pass outer membrane
what helps the pyruvate acorss iner membrane into the matrix. Where does it get its energy from
transsport protein: H+/pyruvate symport protein
-uses enegry released from corssing protons
what does oxidation of pyruvate produce PER pyruvate
1 acetyle CoA
-1 CO2
-1 NADH
what is oxidation of pyruvate catalyzed by
a large enzyme complex that catalyzes 3 enzymatic rxns at once
net energy yield (for glucose catabolism)
2 CoA
-2 CO2
-2NADH
describe acetyle CoA moleq
-high energy bond (S)
-nucleotide at end
acetyle CoA from pyruvate oxidation step feeds into the what
citric acid cycle
what is citric acid cycle also called
Krebs cycle
what does citric acid cycle complete the breakdown of
pyruvate to CO2. the cycle oxidizes organic fuel derived form acetyle CoA.
1 cycle or “turn” beginning with the entry of acetyle CoA yields what
-2 CO2
-1 ATP
-3 NADH
-1 FADH2
how many steps does citric cycle have
8 steps, each catalyzed by a specific enzyme
how is citrate formed
the acetyle group of acetyle CoA joins the cycel by combining with oxaloacetate forming citrate
what happens after citrtae is formed
the next 7 steps decompose citrate back to oxalcactat making process a cycle
what do the NADH and FADH2 prduced by the cycle relay
high energy e- extratcted from food to e- transport chain
what is made by substrate level phosphorylation
ATP
summary of aerobic respiration so far wth glycolysis and citric acid cycle
Glcose (6-c) kickstarts glycolysis which produces 2 pyruvate + 2 ATP + 2NADH.
The 2 pyruvate help make 2 Acetyle CoA initiating the citric acid cyel which produces 2 ATP + 6 NADH + 6 CO2 + 2 FADH2
