lecture 16 part 2 Flashcards

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1
Q

glucose homeostasis is under

A

extrinsic regulation

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2
Q

glucose homeostatsis is controlled by

A

a factor outside of the cells

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3
Q

hormone sthta regulate blood glucose levels

A

insuline and glucagon

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4
Q

insulin

A

made by beta islet cells of pancreas

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5
Q

glucagon

A

made by alpha islet cells of pancreas

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6
Q

glucose levels go back to normal quickly b/c of

A

beta cells of pancreas

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7
Q

beta cells of pancreas are snesitive to what

A

blood glucose []

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8
Q

elevated blood glucose [] causes what

A

beta cells to release inculin into bloodstream

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9
Q

insulin cells simtulates cells to what

A

take up glucose
-liver cells, muscle cells, and adipocytes

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10
Q

how does insulin stimulate liver cells

A

to convert glucose into glycogen and stop ocnverting glycogen into glucose

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11
Q

what does insulin promote

A

fatty acid synthesiis from glcose in liver (when it has enoug hglycogen)

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12
Q

unslin promotes glycerol production in

A

adipocytes

-with fatty acids form liver, these cells can make triaglycerides

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13
Q

glucagon are released from

A

alpha islet cells of the pancreas into bloodstrem whne blood glucose levels drop

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14
Q

what does glucagon bind

A

glucagon receptors on liver cells sending a signal that activates on enzyme that hydrolyzes glycogen, releasing glucose (glycogenolysis)

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15
Q

glucose goes out of liver cells and into the bloodstrea via

A

facilitated diffusion

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16
Q

when insulin binds to its receptors, it signals for what

A

vesciles containing the glucose transporter to go to the cell surface so the trasnporter can allow the glucose to enter the cell via facilitated diffusion

17
Q

glut-4

A

glucose transporter

18
Q

what happens after a while to Glut-4

A

it will be recyledd and more insulin will be needed to allow glucose to enter cell

19
Q

what is diabetes

A

elevated blood glucose levels becaise cells can not import glucose due to lack of glut-4

20
Q

adipose and muscle cells express lots of what

A

glut-4

21
Q

what are the two types of diabetes

A

Type I and type II

22
Q

type I diabetes

A

beta cells do not produce enough insulin, immune system destroys the bodys ow beta cells (autoimmune disease)

23
Q

type II diabetes

A

bodys cells become insensitive to insulom
-bodys insulin may not bind to receptor
-insulin may bind but signaling to vesciles w/ glut-4

24
Q

is type II or type I diabetes more common

A

type II