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Microbiology > Lecture 25: Bordetella and Camplyobacter > Flashcards

Lecture 25: Bordetella and Camplyobacter Flashcards

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Biology 101 flashcards
1
Q

Kennel cough is a multifactorial disease that includes __ and ___

A
  1. Stress
  2. Infection with B. Bronchiseptica
  3. Canine pneumovirus
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2
Q

Bordetella is an extra cellular commensal in ___ of mammals and birds

A

Upper respiratory tract

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3
Q

Bordetella is a ___pathogen

A

Opportunistic

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4
Q

Bordetella is a gram ___, strictly ___

A

Negative, aerobic

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5
Q

Bordetella is catalase and oxidase ___

A

Positive

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6
Q

Bordetella has tropism for ___epithelium

A

Ciliated respiratory epithelium

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7
Q

How is Bordetella transmitted

A

Aerosol

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8
Q

What are the 3 virulence factor toxins associated with Bordetella

A
  1. Tracheal cytotoxin
  2. Dermonecrotic toxin
  3. Osteotoxin
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9
Q

What does tracheal cytotoxin do

A

Inhibits movement of cilia and tracheobronchial clearance. Can kill ciliated cells

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10
Q

What does dermonecrotic toxin do

A

Induces dermal necrosis and interferes with differentiation of osteoblasts leading to turbinate atrophy

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11
Q

What does osteotoxin do

A

Kills osteoblasts

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12
Q

What does B. Bronchiseptica cause in pigs

A

Atrophic rhinitis- turbinate hypoplasia

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13
Q

Bordetella Bronchiseptica causes atrophic rhinitis in pigs with co-infection with ___

A

P. Multocida

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14
Q

What disease does B. Bronchiseptica cause in dogs

A

Canine infectious tracheobronchitis

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15
Q

What does B. Avium cause in turkeys

A

Coryza

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16
Q

What are the clinical signs of kennel cough/ canine infectious tracheobronchitis

A

Coughing, retching, mild serous oculonasal discharge

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17
Q

What are the symptoms of Turkey coryza

A
  1. Beak breathing
  2. Sneezing
  3. Tracheal collapse
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18
Q

Turkey coryza predisposes birds to ___

A

Secondary infections- E. Coli

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19
Q

How do you dx Bordetella

A

Culture/ PCR of
1. Tracheal fluid
2. Sinus exudate

20
Q

How do you tx and prevent Bordetella Bronchiseptica in dogs

A
  1. Isolate and monitor for 2 weeks then try amoxicillin
  2. Vaccinate
21
Q

What can you add to poultry’s water to increase hygiene measures against Bordetella

A

Chlorine

22
Q

Antimicrobials are infective against what Bordetella infection

A

Turkey coryza/ B. Avium

23
Q

Where is camplyobacter found

A

Intestinal and genital tracts

24
Q

Camplyobacter causes ___ or ___

A

Diarrhea or abortion

25
Q

What does C. Fetus subspecies venerealis cause and in who

A

Bovine reproduction tract—abortions, infertility

26
Q

What does C. Fetus subspecies fetus cause and in who

A

GI tract of ruminants (especially sheep)— abortions

27
Q

What does C. Jejuni cause and in who

A

GI of most species- abortions and enteritis

28
Q

Outbreaks of Venereal disease: C. Fetus, C. Venerealis, and C. Jejuni are commonly where

A

Western states

29
Q

What Camplyobacter causes diarrheal disease

A

C. Jejuni

30
Q

Which Camplyobacter is a reportable disease

A

C. Jejuni

31
Q

What are the virulence factors associated with Camplyobacter

A
  1. Microcapsule
  2. S layer
32
Q

What does the micro capsule do

A

Reduces susceptibility to complement and phagocytosis

33
Q

What does the S layer do

A

Immune evasion- has 8 variants

34
Q

What are the clinical manifestations for bovine genital camplyobacteriosis

A
  1. Temporary infertility
  2. Abortion
35
Q

___are asymptomatically infected carriers for C. Venerealis

A

Bulls

36
Q

1/3 of cows affected with C. Venerealis carry disease long term, what causes the persistent infection

A

S layer- immune evasion

37
Q

Persistent infection with C. Venerealis can cause __ if bacteria migrate to ___

A

Permanent infertility, oviducts (salpingitis)

38
Q

What are the clinical manifestations of ovine genital camplyobacteriosis

A
  1. Abortion in ewes
  2. Necrotic placentitis
39
Q

What are the clinical manifestations of canine intestinal camplyobacteriosis

A
  1. Most are subclinical
  2. Enteritis in puppies < 6m months
40
Q

What Camplyobacter can cause Avium vibrionic hepatitis- spotty or necrotic liver

A

C. Jejuni

41
Q

How do you dx camplyobacter spp

A
  1. Vaginal flush with LRS
  2. PCR
  3. Culture
42
Q

The culture for Camplyobacter requires __conditions

A

microaerophilic

43
Q

What agar is selective for C. Jejuni

A

Skirrow agar

44
Q

What is the treatment/ prevention for C. Fetus

A
  1. Therapeutic vaccination
  2. Isolate ewes
  3. Chlortetracycline
45
Q

What is treatment/ prevention for c. Venerealis

A
  1. Dihydrostreptomycin
  2. Pre/post breeding vaccination
46
Q

What is tx/ prevention for C. Jejuni

A
  1. Dihydrostreptomycin
  2. Fluids and antibiotics for dehydrated puppies

Microbiology (31 decks)

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