Lecture 2: ANATOMY OF SKIN - Part 2 Flashcards

1
Q

Where is hair found?

A

All over the body (only prominent on the head) except palms of hands and soles of feet

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2
Q

What does hair consist of?

A

Hair shaft, hair follicle, arrector pili muscle and sebaceous gland

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3
Q

What happens when the arrector pili muscle contracts?

A

Causes the hair to raise

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4
Q

What does a sebaceous gland do?

A

Produce sebum which acts as a natural moisturiser/water repellent

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5
Q

Where is sebum produced more?

A

On the head, shoulders and face

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6
Q

What is lanolin?

A

Sheep sebum which is used in skincare

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7
Q

What is acne?

A

Blockage of hair follicles and infection

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8
Q

What does increased sebum do?

A

Increase the risk of acne

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9
Q

What are the two types of sweat glands?

A

Eccrine and apocrine

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10
Q

Where are eccrine glands?

A

Everywhere

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11
Q

What is the role of eccrine glands?

A

Thermoregulation

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12
Q

What is the role of apocrine glands?

A

Specialised

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13
Q

Where are apocrine sweat glands?

A

Situated deeper in the skin, release into base of the hair follicle

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14
Q

How are apocrine secretions described?

A

Oily

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15
Q

What are the 3 types of receptors?

A

Tactile, lamellar and bulbous

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16
Q

What receptor is deeper?

A

Lamellar are deeper than tactile receptors

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17
Q

What do nails do?

A

Protect fingertips and enhance sensation

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18
Q

What do sensory receptors require?

A

Deformation

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19
Q

What does high pigmentation do?

A

Protects from UV radiation

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20
Q

What does low pigmentation do?

A

Helps with vitamin D production

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21
Q

What does melanin pigment do?

A

Absorbs UV light to protect from UV damage (damage DNA)

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22
Q

Where is melanin produced?

A

In cells called melanocytes

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23
Q

How is melanin transported?

A

By melanosomes (vesicles) to the epidermal cells

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24
Q

Where are melanocytes found?

A

Only in the stratum basale

25
Do melanocytes shed?
No
26
Where are melanosomes found?
Throughout the epidermis
27
Do melanosomes shed?
Yes. With the keratinocytes
28
Where does the density of melanocytes vary?
Throughout the body but not between races
29
What is a mole?
Cluster of melanocytes
30
What causes a mole?
Overproliferation can be cause by sun exposure
31
What is a freckle?
Melanocytes overproducing melanosomes
32
What causes a freckle?
Overproduction triggered by sun exposure
33
What does more UV mean?
More pigment
34
What does less UV mean?
Less pigment
35
What is vitamin D deficiency?
Rickets
36
What is vitamin D essential for?
Normal calcium metabolism and strong bones
37
What does vitamin D deficiency also effect?
Mood
38
What is UV exposure in skin required for?
Vitamin D synthesis
39
Where is there a greater incidence of lightly pigmented skin?
At higher latitudes
40
What people are more susceptible to Vitamin D deficiency?
Highly pigmented people, particularly at extreme latitudes
41
What does New Zealand have one of the highest rates for worldwide?
Skin cancer
42
What proportion of NZers are pakeha (European descent, mostly British)?
Large proportion (74%)
43
What is the UV of NZ?
Intense (elliptical orbit of the sun, latitude, thin ozone)
44
What country also has high skin cancer rates?
Australia
45
What are the types of skin cancer?
Basal cell carcinoma and malignant melanoma
46
How is basal cell carcinoma described?
Common but relatively benign
47
Where does basal cell carcinoma originate?
In the stratum basale
48
Metastasis is ______ for basal cell carcinoma?
Rare
49
What is metastatis?
Breaking off and moving to and growing in another part of the body
50
How is Malignant melanoma described?
Rare but deadly if not treated
51
Where does malignant melanoma originate?
In the melanocytes (pigmented)
52
Malignant melanoma is ______ metastatic
Highly
53
What does the mortality rate of malignant melanoma depend on?
The tutor (thickness and depth as it is more likely to get into the circulatory system and cause damage to organs)
54
What is tattoo?
Artificial pigmentation (usually ink) deposited deep within the skin
55
Where is the ink of a tattoo deposited?
Into the dermal layer so it is effective and doesn't shed
56
What is done with the tattoo ink?
It is captured inside the immune cells/scar tissue but not broken down
57
What happens to lymph nodes in tattoo?
They may become pigmented as the tattoo breaks down
58
What are the types of tattoo?
Trauma, decorative and cosmetic (e.g. eyebrows)
59
What is the Polynesian connections of tattoos?
Maori, ta moko | Samoan, Pe'a