Lecture 15: Establishing the Basic Body Plan Flashcards

1
Q

notochord formed from what layer

A

mesenchymal cells

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2
Q

where does the notochord originate

A

the primitive node, mesenchymal cells migrating cranially

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3
Q

where does notochord end

A

prechordal plate

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4
Q

what is the main function of the notochord

A

primary inductor of the embryo

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5
Q

what does the notochord induce in the overlying ectoderm

A

formation of the neural plate

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6
Q

what gives rise to the CNS

A

neuroectoderm

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7
Q

when does the neural groove form

A

day 18

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8
Q

where does fusion of neural tube begin

A

cranially

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9
Q

when do the anterior and posterior neuropore close

A

anterior: day 24-25
posterior: day 27

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10
Q

fate of neural tube

A

forebrain: cerebral hemispheres
midbrain: adult midbrain
hindbrain: pons, cerebellum, medulla oblongata
Rest becomes spinal cord

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11
Q

what are neural crest cells

A

neuroectodermal cells at the crest of the neural folds that detach as neural tube separates from ectoderm. migrate to each side

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12
Q

neural crest cells become

A

DRG, ganglia of ANS, CN V VII IX and X, peripheral nerve sheaths, melanocytes, adrenal medulla, facial muscles/bones

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13
Q

names of mesoderm

A

embryonic (somatic) = paraxial, intermediate, lateral and

extraembryonic (splanchnic) = continues with it

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14
Q

where are the endo and ectoderm not separated by mesoderm

A

oropharyngeal membrane (prechordal plate) and cloacal membrane

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15
Q

when are somites formed

A

end of week 3

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16
Q

what does the paraxial mesoderm become

A

paired blocks called somites

17
Q

where do somites first appear

A

cranially

18
Q

how many pairs of somites by the end of week 5

A

42-44

19
Q

what do somites become

A

axial skeleton, skeletal muscles, dermis

20
Q

how does the body cavity form

A

coelomic spaces in lateral mesoderm and cardiogenic mesoderm. spaces coalesce to form intraembryonic coelom

21
Q

embryonic coelom becomes

A

pericardial cavity (heart), pleural cavity (lungs), peritoneal cavity (abdominal organs)

22
Q

when does angiogenesis begin

A

start of week 3

23
Q

where does angiogenesis begin

A

extraembryonic mesoderm, yolk sac, connecting stalk, chorion

24
Q

how are blood islands formed

A

mesenchymal cells in yolk sac called angioblasts aggregate

25
Q

how is the endothelium of blood vessels formed

A

angioblasts flatten to form endothelium, these fuse to form blood vessels

26
Q

initial blood cells formed from

A

endothelial cells called hemocytoblasts

27
Q

heart and great vessels formed from

A

mesenchyme (cardiogenic area)

28
Q

how/when is the primitive heart tube formed

A

paired endocardial tubes form and fuse

29
Q

when does the heart begin to beat

A

end of week 3

30
Q

allantois

A

outpouching of yolk sac into the connecting stalk, becomes bladder