LEC3 - ENZYME 3

Question 1

is an enzyme is involved in energy storage of tissues.

Answer 1

creatine kinase

Question 2

CK’s cofactor

Answer 2

magnesium

Question 3

creatine + ADP rsults from

Answer 3

creatine phosphate aand ATP using ck as enzyme

Question 4

During periods of rest, ATP is converted to _____ by CK to serve as energy reservoir.

Answer 4

creatine phosphate

Question 5

phosphorylation reservoir of creatine kinase

Answer 5

ADP

Question 6

products in active muscle

Answer 6

creatine and ATP

Question 7

3 major isoenzyme for ck

Answer 7

brain type of CK

Question 8

isoenzyme found n brain and smoothmscle

Answer 8

ck1 or ckbb

Question 9

ck2 are focus in

Answer 9

cardiac muscle

Question 10

ck2 is also known as

Answer 10

ckmb

Question 11

ck3 is found in

Answer 11

skeletal muscle

Question 12

ck2 is aslo known as

Answer 12

ckmb

Question 13

most rapidly moving isoenzyme of CK

Answer 13

CKbb

Question 14

Among the 3 which ck isoenzyme is the slowest

Answer 14

ck MM

Question 15

which chromosome is a prduct of ck bb

Answer 15

loci 14

Question 16

loci of ck mb

Answer 16

chromosome 19

Question 17

loci of ck t

Answer 17

chromosome15

Question 18

majority of creatinine kinase we are getting are from

Answer 18

mb and mm

Question 19

first enzyme after the onset of signs and symptoms of MI

Answer 19

creatinine kinase

Question 20

gold standard for MI

Answer 20

troponin I and T

Question 21

causes highest elevation of total ck

Answer 21

duchenne’s muscular dystrophy

Question 22

method of chice for ck but not routinely used

Answer 22

electrophoresis

Question 23

assay that uses antibodies against ck m subnit

Answer 23

immunoinhibition assay

Question 24

antibody used to detect the presence of ck

Answer 24

anti-ck-m

Question 25

most commonly used assay for ck which inhibits ck M

Answer 25

mass immunoassay

Question 26

(Forward Direct method of ck)

Answer 26

Tanzer-Gilvarg Assay

Question 27

(Reverse/indirect method of ck )

Answer 27

Oliver-Rosalki method

Question 28

which one is faster,reverse or direct for cl

Answer 28

reverse - Oliver-Rosalki method6x faster

Question 29

is ck light sensitive

Answer 29

yes

Question 30

anticoagulants that inhibits ck action

Answer 30

oxalates and fluoride

Question 31

compunds enhibiting ck activity

Answer 31

mn, ca, zinc, copper

Question 32

can urate and citrate inhibts tthe sample CK

Answer 32

yes

Question 33

CK levels are increased in:

Answer 33

Progressive muscular dystrophy
necrosis, muscle

Acute psychosis
Alcoholic myopathy
Delirium tremens
Hypothyroidism
Malignant hyperthermia
Acute cerebrovascular disease
Trichinosis and dermatomyositis