LEC3 - ENZYME 3

Question 1

is an enzyme is involved in energy storage of tissues.

Answer 1

creatine kinase

Question 2

CK’s cofactor

Answer 2

magnesium

Question 3

creatine + ADP rsults tp

Answer 3

creatine phosphate aand ATP using ck as enzyme

Question 4

phosphorylation reservoir of creatine kinase

Answer 4

ADP

Question 5

3 major isoenzyme for ck

Answer 5

brain type of CK

Question 6

isoenzyme found n brain and smoothmscle

Answer 6

ck1 or ckbb

Question 7

ck2 are focus in

Answer 7

cardiac muscle

Question 8

ck2 is also known as

Answer 8

ckmb

Question 9

ck3 is found in

Answer 9

skeletal muscle

Question 10

ck2 is aslo known as

Answer 10

ckmb

Question 11

most rapidly moving isoenzyme of CK

Answer 11

CKbb

Question 12

Among the 3 which ck isoenzyme is the slowest

Answer 12

ck MM

Question 13

which chromosome is a prduct of ck bb

Answer 13

loci 14

Question 14

loci of ck mb

Answer 14

chromosome 19

Question 15

loci of ck t

Answer 15

chromosome15

Question 16

majority of creatinine kinase we are getting are from

Answer 16

mb and mm

Question 17

first enzyme after the onset of signs and symptoms of MI

Answer 17

creatinine kinase

Question 18

gold standard for MI

Answer 18

troponin I and T

Question 19

causes highest elevation of total ck

Answer 19

duchenne’s muscular dystrophy

Question 20

method of chice for ck but not routinely used

Answer 20

electrophoresis

Question 21

assay that uses antibodies against ck m subnit

Answer 21

immunoinhibition assay

Question 22

antibody used to detect the presence of ck

Answer 22

anti-ck-m

Question 23

most commonly used assay for ck which inhibits ck M

Answer 23

mass immunoassay

Question 24

(Forward Direct method of ck)

Answer 24

Tanzer-Gilvarg Assay

Question 25

(Reverse/indirect method of ck )

Answer 25

Oliver-Rosalki method

Question 26

which one is faster,reverse or direct for cl

Answer 26

reverse - Oliver-Rosalki method6x faster

Question 27

is ck light sensitive

Answer 27

yes

Question 28

anticoagulants that inhibits ck action

Answer 28

oxalates and fluoride

Question 29

compunds enhibiting ck activity

Answer 29

mn, ca, zinc, copper

Question 30

can urate and citrate inhibts tthe sample CK

Answer 30

yes

Question 31

CK levels are increased in:

Answer 31

Progressive muscular dystrophy
necrosis, muscle

Acute psychosis
Alcoholic myopathy
Delirium tremens
Hypothyroidism
Malignant hyperthermia
Acute cerebrovascular disease
Trichinosis and dermatomyositis