Language of Medicine - Chapter 14 Flashcards

Lymphatic and Immune System

1
Q

define lymph

A

clear, watery fluid that surrounds the body cells + flows in a system in the thin-walled lymph vessles that extends throughout the body

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2
Q

which wbc are rich in lymph?

A

lymphocytes + monocytes

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3
Q

what does lymph contain?

A

water, salts, sugar, wastes of metabolism (urea + creatine)

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4
Q

define interstitial fluid

A

fluid that surrounds the body cells

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5
Q

what are the functions of the lymphatic system?

A
  1. drainage system to transport needed proteins + fluid that have leaked out of the blood capillaries back to bloodstream via veins
  2. lymphatic vessels in intestines absorb lipids from the small intestines + transport them to bloodstream
  3. defence of body against foreign organisms (bacteria + viruses)
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6
Q

define lymph capillaries

A

begin at spaces around cells throughout the body
- thin walled tubes
- carry lymph from tissue spaces to larger lymph vessels

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7
Q

fine lymph vessels

A

thicker walls than lymph capillaries
- contain valves so that lymph flows in one direction

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8
Q

define lymph nodes

A

collections of stationary lymph tissue
- located along the path of lymph vessels
- produce lymphocytes + filter lymph + tap substances from infectious, inflammatory + cancerous lesions

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9
Q

where are cervical lymph nodes located

A

neck

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10
Q

where are axillary lymph nodes located

A

armpit

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11
Q

where are mediastinum lymph nodes located

A

chest

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12
Q

where are mesenteric lymph nodes located

A

intestinal

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13
Q

where are paraaortic lymph nodes located

A

lumbar

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14
Q

where are inguinal lymph nodes located

A

groin

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15
Q

define tonsils

A

masses of lymph tissue in the throat near the back of the mouth

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16
Q

define adenoids

A

enlarged lymph tissue in the part of the throat near the nasal passages

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17
Q

where is the right lymphatic duct + thoracic duct located?

A

upper chest

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18
Q

define B lymphocytes (B cells)

A

fight disease
- present in the nodes
- produce antibodies
- originate in bone marrow

19
Q

define T lymphocytes (T cells)

A

attack bacteria + foreign cells by accurately recognizing a cell as foreign + destroys it
- help B cells make antibodies
- originate in thymus gland

20
Q

define the spleen

A

located in the LUQ
- next to stomach
functions:
- destruction of old erythrocytes by macrophages (hemoglobin converted to bilirubin in liver and excreted into bile)
- filtration of microorganisms + other foreign material from the blood
- activation of lymphocytes (B cells produce antibodies - T cells attack foreign material)
- storage of blood (especially erythrocytes + platelets)

21
Q

define thymus gland

A

located in upper mediastinum between lungs
- during fetal / child life it is large - becomes smaller with age
function:
- ability to protect body from disease (especially in childhood)

22
Q

define immune system

A

specialized system to defend the body against antigens (toxins, bacterial proteins, foreign blood cells)
includes:
- leukocytes, neutrophiles, monocytes, macrophages, lymphoid organs like lymph nodes, spleen, thymus gland, and adenoids, produce lymphocytes + antibodies

23
Q

define immunity

A

body’s ability to resist foreign organisms + toxins that damage tissues + organs

24
Q

define natural immunity

A
  • resistance present at birth
  • not dependent on previous exposure to an antigen
    neutrophils travel to infected area + ingest bacteria while monocytes, macrophages + lymphocytes (NK cells) participate in body’s natural immunity against infection
25
define adaptive immunity
- can be developed - body's ability to recognize + remember specific antigens in an immune response - T cells recognize + remember antigens to produce stronger more rapid attacks - B cells secrete antibodies against the antigens
26
define antitoxins
ready made antibodies produce in another organism
27
define maternal antibodies
infants can receive maternal antibodies through the placenta before birth or in breast milk
28
what are the 2 component of adaptive immunity?
1. humeral immunity involves B cells 2. cell-mediated immunity involves T cells
29
define plasma cell
when a B cell matures it is called a plasma cell - plasma cell produces immunoglobulins
30
examples of immunoglobulins
- IgG - IgA - IgM (maternal) - IgE (allergic reactions) - IgD
31
define cell-mediated immunity
does not involve antibodies, involves several different T cells with different functions - cytotoxic T cells (CD8+T cells) attach to antigens + directly kills cells expression antigen, they also secrete cytokines which aid other cells in antigen destruction - helper T cells (CD4+T cells) assist B cells in making antibodies + stimulate T cells to attack antigens - suppressor T cells (regulatory T cells) inhibit both B + T cells to prevent them from attacking the body own good cells
32
define complement system
group of proteins that helps antibodies kill their target
33
define dendritic cell
initiates adaptive immunity by presenting antigens to T + B cells
34
define monoclonal antibodies (MoAb)
antibodies created in laboratory by special reproductive techniques - designed to attack specific cancer cells directly or to activate T cells to kill tumour
35
define vaccines
contain antigens (proteins) from a patients tumour cells or from infectious agent. - when injected they stimulate patients own T cells to recognize + kill cancerous cells
36
define transfer of immune cells
in bone marrow transplant, T lymphocytes from donor replace patients immune system with new cells that recognize tumours as foreign
37
immun/o
protection
38
lymph/o
lymph
39
lymphaden/o
lymph node
40
splen/o
spleen
41
thym/o
thymus gland
42
tox/o
poison
43
ana--
again, new
44
inter--
between