L23: Cancer Flashcards
Def of Cancer
Indicators of population impact of Cancer
Worldwide, cancer is a leading cause of death.
…
More than 70% of all cancer deaths occurred in ……
low & middle income countries
In developed countries, it is the …. leading cause of death next to CVD
2nd
In developing world, it is the …. cause of death.
4th
There is steady Increase in incidence and mortality of cancer that could be explained by:
❶ Advanced techniques for case-finding & detection
❷ Marked demographic aging
❸ Changes in life style & environment
The most frequent types of cancer In Males worldwide are
lung, stomach, liver, colorectal, oesophagus, prostate
The most frequent types of cancer In Females worldwide are
breast, lung, stomach, colorectal and cervical
Etiology of Cancer
The definite etiology of cancers in man are unknown
RF of Cancer
Genetic Factors Predispsoing to Cancer
Genetic Factors Predispsoing to Cancer
- Familial Tendency
there are familial tendencies for certain cancer as cancer breast, colon, prostate & lung
Genetic Factors Predispsoing to Cancer
- Chromosomal Deletion
- deletion of chromosome 13 in retinoblastoma
- deletion of chromosome 11 in Wilms’ tumor.
Environmental Factors Predispsoing to Cancer
Environmental Factors Predispsoing to Cancer
- Physical Factors
Environmental Factors Predispsoing to Cancer
- Physical Factors (Radiation)
Environmental Factors Predispsoing to Cancer
- Physical Factors (Mechsnical Factors)
include
❶ Chronic friction.
❷ Trauma, irritation .
❸ Inflammation as peptic ulcer & chronic cervicitis
Environmental Factors Predispsoing to Cancer
- Chemical Factors
Environmental Factors Predispsoing to Cancer
- Physical Factors (Tobacco)
Increased risk of cancer lung, mouth, larynx, stomach, pancreas & urinary bladder