L19: Bacterial Food-Borne Infections Flashcards
CA of Typhoid
salmonella typhi (107 types)
CA of Paratyphoid
Salmonella paratyphi
- A (frequent)
- B (the most common)
- C (rare)
Reservoir of Typhoid & Paratyphoid
Most Dangerous Reservoir of Typhoid
Chronic carriers are the most dangerous
Chronic Carriers of Typhoid
IP of Typhoid
Study MOT of Typhoid & Paratyphoid
14 days, but this depends on the infective dose can vary from 3 days to 1 month
IP of Paratyphoid
Paratyphoid fever is usually 1-10 days.
Susceptible Age of Typhoid
Susceptibility is general
Infectivity Period of Typhoid
From last few days of I.P. & as long as the organism appear in excreta. (Variable in typhoid)
Infectivity Period of Paratyphoid
1-2 weeks for paratyphoid
Susceptible sex for Typhoid
more cases among males, but carrier state is more in females
Immunity to Typhoid
develop after infection (clinical or subclinical) or immunization.
Susceptible environment for Typhoid
occurs all over the year with high incidence in late summer & early autumn.
General Prevention of Typhoid
with referral to general epidemiology.
❶ Environmental sanitation
❷ Health education of the public.
Specific Prevention of Typhoid
- Vaccination
Vaccination for Typhoid
- Nature
Vaccination for Typhoid
- Dose
❶ Oral typhoid vaccine: 3-4 doses, 2 days apart.
❷ Polysaccharide vi antigen vaccine: single subcutaneous dose is available
Vaccination for Typhoid
- Indication
Vaccination for Typhoid
- Protective Value
moderate for all preparations.
Composition of TAB Vx
- 1 ml contain 1000 million S. typhi
- 750 million S.paratyphi A & B
Composition of TABC Vx
- 1 ml contain 1000 million S. typhi
- Where paratyphi C is endemic, 750 million organisms are added
Composition of Typhoid Vx
1 ml contain 1000 million S. typhi
Case Control Measures for Typhoid
Contact Control Measures for Typhoid
Carrier Control Measures for Typhoid
Epidemic Control Measures for Typhoid
Case Control Measures for Typhoid
- Notification
local health office
Case Control Measures for Typhoid
- Isolation
at fever hospital or at home
Case Control Measures for Typhoid
- TTT
with appropriate antibiotics
Case Control Measures for Typhoid
- Release
after clinical & bacterial cure (3 -ve stool & urine cultures 2 weeks after fever)
Case Control Measures for Typhoid
- Disinfection
concurrent (for urine & stool, articles) & terminal
Contact Control Measures for Typhoid
- Survaillence
3 weeks from exposure for early case & carrier finding
International Measures for Typhoid
Typhoid vaccination is recommended for travelers to endemic areas
Def of Brucellosis
CA of Brucellosis
Reservoir of Brucellosis
Infected animals; cattle, goats & sheep & pigs. No man reservoir
MOT of Brucellosis
MOT of Brucellosis
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IP of Brucellosis
Highly variable & difficult to ascertain 5-60 days
Infectivity Period of Brucellosis
No man to man transmission
Susceptible Age for Brucellosis
All ages
Susceptible Sex for Brucellosis
Both sexes
Immunity to Brucellosis
Severity & duration of clinical illness are subject to wide variation, Duration of acquired immunity is uncertain
Preventive Animal Measures for Brucellosis
Preventice Human Measures for Brucellosis
Case Contact Measures for Brucellosis
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Case Contact Measures for Brucellosis
- Isolation
no need for isolation
Contact Contact Measures for Brucellosis
Outbreak Measures for Brucellosis
❶ Trace source of infection (e.g. milk products).
❷ Restricted distribution of unpasteurized milk & milk products is enforced.
International Measures for Brucellosis
Quarantine measures for imported animals.
Def of Bloody diarrhea
Bloody diarrhea: is a significant cause of illness and death in young children, particularly those who live in less-developed countries.
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Causes of Bloody Diarrhea
Def of Shigellosis
Shigellosis is a highly infectious intestinal disease caused by a family of bacteria called shigella
CA of Shigellosis
there are four types of shigella (S. dysenteriae, S. flexneri, S. boydii and S. sonnei).
Reservoir of Shigellosis
only human
IP of Shigellosis
12-96 hours
MOT of Shigellosis
Def of Enterohemorrhagic E-coli
Enterohemorrhagic E. coli (EHEC) or shiga toxin-producing E is one of E-coli strains that cause severe intestinal infection in human .
Enterohemorrhagic E-coli id different from other E. coli because it makes a …… called shiga toxin.
potent toxin
This toxin damages the lining of the intestinal wall, causing bloody diarrhea.
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CA of Enterohemorrhagic E-coli
Enterohemorrhagic E-coli.
Reservoir of Enterohemorrhagic E-coli
human (in the form case and carrier) cattle goat and sheep
Source of Infection of Enterohemorrhagic E-coli
stool of infected persons.
MOT of Enterohemorrhagic E-coli
IP of Enterohemorrhagic E-coli
2-10 days
Prevention & control for bloody diarrhea
International measures for bloody diarrhea
Done
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