Intro-Immune system Flashcards

1
Q

What are the 4 challenges pathogens present the immune system with?

A

1-Form diversity
2-Life cycle diversity
3-Diverse routes of infection
4-Rapid, targeted response over a broad domain

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2
Q

Rapid response, Limited number of specificities and being constant during response is typical for what response?

A

Innate immunity

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3
Q

Slow response, variable, numerous highly selective specificities and improving during response is typical of what response?

A

Adaptive immunity

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4
Q

Which hematopoietic line is adaptive?

A

Lymphoid precursor

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5
Q

Which hematopoietic line is innate?

A

Myeloid precursors

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6
Q

Plasma cells and effecter T cells are what?

A

Lymphocytes

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7
Q

Macrophages and dendritic cells are what?

A

Monocytes

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8
Q

Neutrophils, eosinophils, mast cells and basophils are what?

A

Granulocytes

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9
Q

What three cells are primary antigen presenting cells in lymph nodes?

A

Dendritic cell, Macrophages, B lymphocyte

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10
Q

Where are naive lymphocytes activated?

A

In lymph nodes

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11
Q

T lymphocytes are co-stimulated through antigen receptor binding by what?

A

Dendritic cells

*T cell proliferates and differentiates to acquire effector function

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12
Q

B lymphocytes are activated through antigen receptor binding by what?

A

T lymphocytes

*B cell to proliferation and differentiation of B cell to acquire effector function

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13
Q

CD8 T cells are cytotoxic and recognizes what?

A

MHC class I and kills infected cells

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14
Q

CD4 T cells are regulatory and recognize what?

A

MHC class II and activates B cells(Helper T cell) or macrophages(Th1)

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15
Q

Activated B cells produce?

A

Antibodies

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