Intro-Immune system Flashcards
What are the 4 challenges pathogens present the immune system with?
1-Form diversity
2-Life cycle diversity
3-Diverse routes of infection
4-Rapid, targeted response over a broad domain
Rapid response, Limited number of specificities and being constant during response is typical for what response?
Innate immunity
Slow response, variable, numerous highly selective specificities and improving during response is typical of what response?
Adaptive immunity
Which hematopoietic line is adaptive?
Lymphoid precursor
Which hematopoietic line is innate?
Myeloid precursors
Plasma cells and effecter T cells are what?
Lymphocytes
Macrophages and dendritic cells are what?
Monocytes
Neutrophils, eosinophils, mast cells and basophils are what?
Granulocytes
What three cells are primary antigen presenting cells in lymph nodes?
Dendritic cell, Macrophages, B lymphocyte
Where are naive lymphocytes activated?
In lymph nodes
T lymphocytes are co-stimulated through antigen receptor binding by what?
Dendritic cells
*T cell proliferates and differentiates to acquire effector function
B lymphocytes are activated through antigen receptor binding by what?
T lymphocytes
*B cell to proliferation and differentiation of B cell to acquire effector function
CD8 T cells are cytotoxic and recognizes what?
MHC class I and kills infected cells
CD4 T cells are regulatory and recognize what?
MHC class II and activates B cells(Helper T cell) or macrophages(Th1)
Activated B cells produce?
Antibodies