Infertility and Assisted Conception

Question 1

What is assisted conception treatment?

Answer 1

any treatment which involved gametes outside the body

Question 2

What is the limit on alcohol before ACT?

Answer 2

femalres limit to 4 units

Question 3

What is the weight restrictions for male and females before ACT?

Answer 3

between 19-29

Question 4

When should folic acid be taken in ACT?

Answer 4

preconception-12 weeks gestation

Question 5

What are the indications for intrauterine insemination?

Answer 5

generally because unable to have penetrative sex but everything else is okay

Question 6

How is intrauterine insemination carried out?

Answer 6

prepared semen inserted into uterine cavity aroudn time of ovulation

Question 7

What are the indications for IVF?

Answer 7

unexplained infertility >2 years; pelvic disease; anovulatory infertility (after failed induction); male factor infertility ; pre-implantation genetic diagnosis

Question 8

What drug is given during IVF?

Answer 8

GnRH analogues

Question 9

What are the SE of GnRH analogues?

Answer 9

hot flushes and mood swings; nasal irritation; HA

Question 10

How are the ovaries stimulated during IVF?

Answer 10

gonadotrophin hormone cantaing either synethic or urinary gonadotrophins (FSH +/- LH)

Question 11

What is the function of hCG injection in IVF?

Answer 11

mimics LH causing resumption of meiosis in oocyte, 36 hours before oocyte recovery

Question 12

How long should men be abstinent before collection of semen?

Answer 12

72 hours

Question 13

What is semen assessed for?

Answer 13

volume; density; motility; progression

Question 14

What are the risks associated with oocyte collection?

Answer 14

bleeding; pelvic infection and failure to obtain oocytes

Question 15

How many embyros are typically transferred?

Answer 15

1

Question 16

What is given for luteal support?

Answer 16

progestrone suppositories for 2 weeks

Question 17

When should a pregnancy test be aken ?

Answer 17

16 days after oocyte recovery

Question 18

How many days after oocyte collection is embryo transferring done?

Answer 18

5

Question 19

What are the indications for intracytoplasmic sperm injection?

Answer 19

severe male factor infertility; previous failed fertilisation with IVF; preimplantation genetic diagnosis

Question 20

What procedure is done with azoospermia?

Answer 20

surgical sperm aspiration

Question 21

Where is sperm aspirated with obstructive azoospermia?

Answer 21

epididymis

Question 22

Where is sperm aspirated with non-obstructive azoospermia?

Answer 22

testicular tissue

Question 23

How many sperm are needed for an IVF cycle?

Answer 23

10

Question 24

What is ovarina hyperstimulation syndrome?

Answer 24

enlarged ovaries with excess follicles

Question 25

What are the symptoms of ovarian hyperstimulation syndrome?

Answer 25

abdo pain/bloating; N and D; breathless

Question 26

What are patients with ovarian hyperstimulation syndrome more at risk of?

Answer 26

VTE

Question 27

How common is failed fertilisation in IVF?

Answer 27

approx 4%

Question 28

What is the IVF success rate?

Answer 28

35%

Question 29

What are the stages of IVF treatment?

Answer 29

down-regulation; ovarian stimulation; oocyte rettrieval; embryo transfer and luteal support

Question 30

What are the complications of IVF?

Answer 30

muliple pregnancy; ovarian hypersensitivty and ectopic pregnancies