Embryology of Genital Tracts Flashcards
Why is the inital stage of genital development referred to as the indifferent stage of genital devleopment?
early genital systems of the two sexes are similar
When does gondal development begin?
week 5
What is the gonadal ridge?
a bulge of proliferating mesonephros
Where do the primordial germ cells originate?
wall of the umbilical vesicle (yolk sac) from the epiblast
How do the primordial germ cells reach the gonadal ridges?
migrate along the mesentery of the hindgut
What happens to the primordial germ cells in the 6th week?
primordial cells enter the underlying mesenchyme and are incorporated into the gonadal cords
What type of substance is mullerian-inhibiting factor?
glycoprotein
What tissue forms the urinary and reproductive systemms?
intermediate mesoderm
What effect does the arrival of the primordial germ cells have on the mesonephros?
stimulates proliferation to form the genital ridge
What is the difference between the medullary and cortical cord development in presence with and without SRY?
with SRY, medullary cords develop whereas in ovary cortical cords develop and medullary degenerate
What forms the medullary gonadal cords?
mesonephric tubule
What forms the cortical cords?
surface epithelium of the gonad
What are the paramesonephric ducts also known as?
Mullerian duct
Which cells secrete mullerian inhibiting substance?
sertoli cells
What other name is given to the mesonephric tubule?
Wolffian ducts