Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Reproduction > Breast Pathology 1 > Flashcards

Breast Pathology 1 Flashcards

1
Q

What is triple breast assessment?

A

clinical; imaging and pathology

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What are the sampling methods for breast cytopatholgoy?

A

FNA; fluid; nipple discharge; nipple scrape

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is C1 on breast FNA cytology?

A

unsatisfactory

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is C2 on breast FNA cytology?

A

benign

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What is C3 on breast FNA cytology?

A

atypia; probably benign

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What is C4 on breast FNA cytology?

A

suspicious of malignancy

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What is C5 on breast FNA cytology?

A

malignant

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What are the diagnostic biopsies for breast histopathology?

A

needle core biopsy; vacuum assisted biopsy; skin biopsy; incisional biopsy of mass

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What are the option for B5 needle core biopsy?

A

B5a- carcinoma in situ

B5b- invasive carcinoma

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What developmental anomalies are seen in the breast?

A

hypoplasia; juvenile hypertrophy; accessory breast tissue; accessory nipple

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is gynaecomastia?

A

breast devlopment in the male

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What seen pathologicall with gynaecomastia?

A

ductal growth without lobular devleopment

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What are the causes of gynaecomastia?

A

exogenous/endogenous hormones; cannabis; prescription drugs; liver disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What age group gets fibrocystic change of the breast?

A

20-50 years but mainly 40-50

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What is fibrocystic change in the breast associated with?

A

menstrual abnormalities–early menarche; late menopause

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

When does fibrocystic change in the breast often resolve or diminish?

A

post-menopause

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
17
Q

What is the presentation of fibrocytic change of the breast?

A

smooth discrete lumps; sudden/cyclical pain; lumpiness

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
18
Q

What is seen on pathology with fibrocystic change?

A

usually multiple blue domed cysts with pale fluid with intervening fibrosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
19
Q

What is the seen microscopically on pathology with fibrocystic change?

A

thin walled cysts- may have fibrotic wall; lined by apocrine epithelium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
20
Q

What is metaplasia?

A

change from one fully differentiated cell type to another fully differentiated cell type

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
21
Q

What is hamartoma?

A

circumscribed benign lesion composed of cell types normal to the breast but in abnormal proportion or distribution

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
22
Q

What race tends to get fibroadenoma?

A

African women

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
23
Q

When is the peak incidence of fibroadenoma?

A

3rd decade

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
24
Q

How do fibroadenomas present?

A

painless; firm; discrete; mobile mass

25
Q

What other name is given to fibroadenomas?

A

breast mosue

26
Q

What is the appearance of fibroadenomas on USS?

A

solid

27
Q

What is seen on pathology with fibroadenoma?

A

circumscribed; rubbery; grey-white; biphasic tumour- epithelium and stroma

28
Q

What are sclerosing lesions of the breast?

A

benign; disorderly proliferation of acini and stroma

29
Q

What makes diagnosis of sclerosing lesions of hte breast?

A

cause a mass or calcification so my mimic carcinoma

30
Q

What is the presentation of sclerosing adenosis?

A

pain; tenderness or lumpiness/thickening; may be asymptomatic

31
Q

What age group gets sclerosing adenosis?

A

20-70

32
Q

What is the prognossi for sclerosing adenosis?

A

benign with negligible risk of carcinoma

33
Q

What is the difference between radial scar and complex sclerosing lesion?

A

radial scar is between 1-9mm; complex sclerosing lesion is >10mm

34
Q

What are the gross features of a radial scar?

A

stellate architecture; central puckering; radiating fibrosis;

35
Q

What are the histological features of a radial scar?

A

fibroelastotic core; radiating fibrosis containind distored ductules; fibrocystic change; epithlelial proliferation

36
Q

What is the treatment for radial scar?

A

excise or sample extensively by vacuum biospy

37
Q

Why is a radial scar excised if it is benign?

A

in situ or invasive carcinoma may occur within the lesion

38
Q

What are the causes of fat necrosis?

A

local trauma- seat belt injury or surgery; warfarin therapy

39
Q

What is seen with fat necrosis of the breast?

A

damage and disruption of adipocytes; infiltration by acute inflammatory cells- “foamy” macrophages; subsequent fibrosis and scarring

40
Q

What are the clinical features of duct ectasia?

A

acute episodic inflammatory changes; bloodt and/or purulent discharge; fistulation and nipple retraction and distortion

41
Q

Which ducts does duct ectasia affect?

A

sub-areolar ducts

42
Q

What are the pathological changes with duct ectasia?

A

sub-areolar duct dilatation; periductal inflammation; periductal fibrosis ; scarring and distortion

43
Q

What is the main risk factor for developing duct ectasia?

A

smoking

44
Q

What is the management of duct ectasia?

A

treat acute infections; stop smoking; excise ducts

45
Q

What are the 2 main causes of acute mastitis/abscess?

A

duct ectasia; lactation

46
Q

What bugs are involved in acute mastitis caused by duct ectasia?

A

mixed organisms and anaerobes

47
Q

What bugs are invovled in acute mastitis caused by lactation?

A

staph. aureus; strep. pyogenes

48
Q

What is the management of acute mastitis/abscess?

A

antibiotics; percut drainage; infection and drainage; treat underlying cause

49
Q

What age group gets Phyllodes tumour?

A

40-50 years

50
Q

What is the clinical feature of phyllodes tumour?

A

slow growing unilateral breast mass

51
Q

What are the types of phyllodes tumour?

A

benign; bordelrine and sarcomatous

52
Q

What are the pathological features of a phyllodes tumour?

A

biphasic; stromal overgrowth

53
Q

What is the prognosis of phyllodes tumour?

A

prone to local reccurence if not adequately excised; rarely metastasise

54
Q

Who gets intraduct papilloma?

A

35-60 years

55
Q

What are the clinical features of intraduct papilloma?

A

nipple discharge +/- blood; nodules; calcification

56
Q

Which ducts does intraduct papilloma affect?

A

sub-areolar ducts

57
Q

What is seen pathologically with intraduct papilloma?

A

papillary fronds containing a fibrovascular core covered with myoepithelium and epithelium- may show proliferative activity

58
Q

What are the different types of epithelial proliferation seen with intraduct papilloma?

A

none; usual type hyperplasia; atypical ductal hyperplasia; ductal carcinoma in situ

Reproduction (52 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions