IM Rheumatology Flashcards

1
Q

What three drugs are approved to treat fibromyalgia?

A

Duloxetine, milnacipran, and pregabalin

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2
Q

What does synovial fluid analysis show in gout?

A

Rod shaped negatively birefringent sodium urate crystals

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3
Q

What is the treatment for an acute gout flare?

A

Indomethacin TID, colchicine.

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4
Q

What are common side effects of colchicine?

A

Diarrhea, GI upset

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5
Q

What medications can trigger a gout flare?

A

Thiazide diuretics, aspirin

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6
Q

What medication is used to prevent gout flares?

A

Allopurinol

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7
Q

What is the most common joint affected by pseudogout?

A

Knees

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8
Q

What does synovial fluid analysis show in pseudogout?

A

Rhomboid-shaped weakly positively birefringent calcium pyrophosphate crystals.

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9
Q

What is the treatment for acute psuedogout flares?

A

NSAIDs

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10
Q

What is the prophylactic treatment for pseudogout?

A

Colchicine

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11
Q

Polyarteritis nodosa is characterized by inflammation of what sized arteries?

A

Small and medium

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12
Q

Describe the typical polyarteritis nodosa patient?

A

40-50 year old men

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13
Q

What antibody is highly associated with polymyositis?

A

Anti Jo-1

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14
Q

What autoantibody is highly sensitive for SLE?

Which are highly specific?

A

ANA is sensitive, not specific.

Anti-dsDNA and anti-Smith are specific but not sensitive

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15
Q

What antibody is highly associated with scleroderma (limited disease)?

A

Anticentromere antibody

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16
Q

What antibody is highly specific for diffuse scleroderma?

A

Anti-topoisomerase I (Anti-Scl70)

17
Q

What antibodies are highly specific for Sjogren syndrome?

A

Anti-Ro (SSA) or anti-La (SSB)

18
Q

What test is used to diagnose Sjogren’s?

A

Schirmer test

19
Q

Patients with Sjogrens are at higher risk for developing what type of cancer?

A

Lymphoma

20
Q

What types of infections can trigger reactive arthritis?

A

GU or GI infections

21
Q

What autoantibody is associated with drug-induced lupus?

A

Anti histone antibody.

22
Q

Describe the deformities in the hand caused by rheumatoid arthritis.

A

Swelling in bilateral MCPs, PIPs, ulnar deviation at MCP, boutonniere deformity, swan neck deformity

23
Q

What rheumatology labs are positive in rheumatoid arthritis?

A

RF or Anti-CCP

24
Q

What rash is pathognomonic for polyarteritis nodosa?

A

Starburst livedo