Family Medicine EOR Flashcards

1
Q

Presenting symptoms of a cervical neck strain?

A

Pain or stiffness with neck movement.

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2
Q

Causes of cervical neck strains?

A

Minor injury or physical stressors such as poor posture or sleep habbits.

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3
Q

Name some red flags when evaluating what you think may be a cervical neck strain?

A

Major trauma, weakness, bowel or bladder dysfunction, cancer symptoms, IVDU, visual changes, anterior neck pain.

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4
Q

Where should you expect tenderness in a cervical neck strain patient?

A

Paraspinal and trapezius muscles.

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5
Q

T/F? You should get a c spine x-ray in evaluation of cervical neck strains.

A

False

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6
Q

Treatment for cervical neck strains?

A

NSAIDs

nonbenzo skeletal muscle relaxers are 2nd line.

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7
Q

How long should a cervical neck strain take to resolve?

A

Within 6 weeks.

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8
Q

Non-pharmacologic treatments for cervical neck strains?

A

Home exercise program, heat or cold, modification of posture.

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9
Q

What medications can result in decreased lower esophageal sphincter pressure, causing GERD?

A

Anticholinergics, antihistamines, CCBs, nitrates, progesterone, and TCAs.

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10
Q

What foods are associated with GERD?

A

Any large meal, acidic foods, alcohol, fatty foods, spicy foods, chocolate, and peppermint.

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11
Q

Name some atypical GERD symptoms.

A

Asthma, chronic cough, chronic laryngitis, sore throat, chest pain, and sleep disturbances.

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12
Q

Concerning GERD features?

A

Dysphagia, odynophagia, weight loss, IDA

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13
Q

Treatment for typical GERD without concerning symptoms?

A

8 week trial of BID H2RA or QD PPI

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14
Q

Patients who do not respond to PPI or H2RA, or have concerning features should have what procedure?

A

Endoscopy.

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15
Q

Gold standard for GERD diagnosis?

A

Esophageal pH testing

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16
Q

Long term PPI use side effects?

A

Infectious gastroenteritis, IDA, Vit B12 deficiency, hympomagnesemia, pneumonia, hip fractures.

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17
Q

Surgical treatment for GERD if pharmacologic therapy is not an option?

A

Surgical fundoplication.

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18
Q

First line therapy for H. pylori?

A

Amoxicillin, clarithromycin, PPI x 14 days

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19
Q

H. pylori is known to cause?

A

Peptic ulcer disease.

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20
Q

In patients age 30-55, where does peptic ulcer disease most commonly cause ulcers?

A

Duodenum

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21
Q

In patients age 55-70, where does PUD most commonly cause ulcers?

A

Gastric

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22
Q

Classic symptom of PUD?

A

Dull, aching, or gnawing epigastric pain

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23
Q

Pain from PUD can be relieved by?

A

Eating

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24
Q

How can you test for H. pylori?

A

Urea breath test or fecal antigen testing

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25
When should a test for cure be done for a patient treated for H. pylori?
4 weeks after completing treatment.
26
Where is an ulcer located if pain is alleviated by ingesting food?
Duodenum
27
Where is an ulcer located if it is exacerbated by ingesting food?
Stomach
28
Is a hordeolum (stye) painful or nonpainful?
Painful
29
Cause of a hordeolum?
Purulent inflammation of the eyelid often due to bacterial infections (staph aureus)
30
Upon inspection of a patients eyelid, you see what appears to be an external hordeolum, however it is not painful. You know that it must be a?
Chalazion
31
Cause of a chalazion?
A blocked oil gland (Meibomian or Zeis gland.)
32
Diffuse inflammation of the eyelid is called?
Blepharitis
33
Most common causes of acute pericarditis?
Enteroviruses including coxsackie, adenoviruses, and parvovirus
34
3 P's of pericarditis chest pain?
Pleuritic, persistent, postural.
35
First line treatment for acute pericarditis?
aspirin or NSAIDs + Colchicine to prevent recurrence
36
EKG findings in pericarditis?
PR elevation in aVR, PR depression, and diffuse ST elevation.
37
What medication can be added in treatment for acute pericarditis for refractory or severe cases?
Corticosteroids
38
Acute pericarditis after a myocardial infarction is known as?
Dressler syndrome
39
First line treatment for Dressler syndrome?
Aspirin and colchicine
40
Most common side effect of colchicine?
GI upset
41
What labs should be ordered to rule out treatable causes of dementia?
Vit B12 level | TSH (hypothyroidism)
42
Two main classes of drugs for treatment of dementia?
Cholinesterase inhibitors and N-methyl-D-aspartate receptor antagonists
43
Name 3 causes of conjunctivitis.
Bacterial, viral, allergic
44
Most common pathogens for bacterial conjunctivitis?
Strep pneumo, H. influenzae, M. catarrhalis, staph aureus.
45
What type of conjunctivitis causes an eye to be "stuck shut" in the morning?
All of them
46
What is the preferred treatment of bacterial conjunctivitis in contact lens wearers?
Fluoroquinalone drops such as moxifloxacin or ofloxacin drops
47
What eye drops can be beneficial in treatment of viral or allergic conjunctivitis?
Topical ophthalmic antihistamines or decongestants, such as ketotifen.
48
A neonate develops severe conjunctivitis 10 days post delivery. What organism do you suspect?
Chlamydia - occurs between 5-14 days of life
49
A neonate develops severe conjunctivitis 3 days post delivery. What organism do you suspect?
Gonorrhea - occurs betewen 2-5 days of life
50
A patient presents with deep-seated itching of the ear 1 week after being treated for otitis externa. What do you suspect?
Fungal external otitis. (otomycosis)
51
What fungi are commonly responsible for fungal external otitis?
Aspergillus and Candida species.
52
Otoscopic evaluation of a patient reveals "fine coal dust" lining the ear canal. What is the most likely organism?
Aspergillus
53
Otoscopic evaluation of a patient reveals a soft white pseudo membrane lining the canal. What is the most likely organism?
Candida
54
Treatment of otomycosis?
Meticulous cleaning and removal of debris, topical antifungals.
55
What is the preferred agent and duration of therapy for treating otomycosis?
Clotrimazole 1% solution BID x 10-14 days
56
What class of medications used to treat otitis externa should be avoided in the presence of tympanic membrane perforation?
Aminoglycosides (tobramycin, gentamycin)
57
Salmonella outbreaks are most commonly associated with?
Poultry and eggs
58
Definitive diagnosis of salmonellosis is made by?
Stool culture
59
Most important component of therapy for salmonellosis?
Replacement of fluids and electrolytes
60
Which virus is associated with outbreaks of gastroenteritis on cruise ships?
Norovirus
61
Differentiating factors between stable and unstable angina?
Stable - predictably triggered, relieved by rest, less than 30 minute duration Unstable - acute onset not relieved by rest, lasts longer than 30 minutes, and not relieved by nitroglycerin.
62
When is a coronary artery bypass graft indicated in coronary artery disease patients?
Left main coronary artery involvement >50% stenosis, >70% stenosis 3 vessel disease, or decreased left ventricular ejection fraction.
63
When is percutaneous transluminal coronary angioplasty indicated for CAD patients?
1 or 2 vessel disease without left main coronary artery involvement
64
What is the gold standard diagnostic test for coronary artery disease?
Coronary angiography
65
What is the cause of syncope?
Inadequate cerbreal blowflow
66
Four main causes of syncope?
Reflex syncope, orthostatic syncope, cardiac dysrhythmias, and structural cardiopulmonary disease.
67
Name some symptoms that accompany reflex syncope.
Lightheadedness, warm or cold, sweating, palpitations, nausea, decreased vision or hearing, pallor.
68
Workup for syncopal episode should include?
H and P, neuro exam, cardiopulmonary exam, EKG
69
Name some cardiac dysrhythmias that may be seen on EKG in patients with syncope.
Brugada syndrome, short QT syndrome, long QT syndrome, preexcitation, and heart block.
70
On a stool ova and parasite test, flagellated trophozoites and cysts are reported. What do you suspect the infection to be?
Giardia lamblia
71
Risk factors for giardia infections?
Wilderness activities, impaired immunity, MSM.
72
Incubation period of giardia?
1-3 weeks
73
First line treatment for Giardiasis?
Metronidazole 250mg TID x 5-7 days tinadazole 2g PO single dose.
74
What patient education can you give on water purification in order to avoid giardia?
Chlorination of water does NOT inactivate cysts. You must filter with a pore size less than 1 mcm or bring water to a boil.
75
A patient presents 7 days after ingestion of river water while camping. Stool ova and parasite test reveals banana shaped motile sporophytes. What organism do you suspect?
Cryptosporidium parvum
76
What is the most common medication for malaria to be resistant to?
Chloroquine
77
Most common patient population to have fibromyalgia?
Women 20-50 years old.
78
Fibromyalgia is commonly associated with what conditions?
RA, hypothyroidism, anxiety, depression.
79
What labs are abnormal in fibromyalgia?
None
80
Nonpharmacologic treatment for fibromyalgia?
CBT, patient education, sleep hygiene, low impact aerobic exercise.
81
Pharmacologic treatment for fibromyalgia?
TCAs, SSRIs, SNRIs, cyclobenzaprine, pregabalin, gabapentin.
82
What are the 3 FDA-approved medications for treatment of fibromylgia?
Duloxetine (SNRI), Pregabalin, and milnacipran.
83
Most common cause of small bowel obstruction?
Adhesions from prior abdominal surgeries.
84
How is diagnosis of small bowel obstruction made?
Abdominal x rays prone and standing. | CT abd also helps determine the severity.
85
Do you suspect a small bowel obstruction patient to be acidotic or alkalotic?
Could be either, acidotic if there is ischemic bowel or dehydration. Alkalotic if patient had hyperemesis.
86
First steps in treatment of small bowel obstruction?
Nasogastric tube | Withdrawal of oral intake
87
What x-ray finding for a small bowel occlusion requires immediate surgery?
Free air in the abdomen indicating a bowel perforation
88
What is the most common cause of a large bowel obstruction?
Neoplasm
89
What do bowels sound like during small bowel obstruction?
High pitched bowel sounds
90
What two specific x-ray terms indicate small bowel obstruction?
Stack of coins or string of pearls sign
91
Most common cause of PID?
STIs (gonorrhea and chlamydia are most common)
92
What exam finding strongly suggests PID?
Cervical motion tenderness | chandelier sign
93
What is the most worrisome complication of PID?
Perihepatitis (Fitz-Hugh Curtis syndrome)
94
First line treatment for PID?
1 time IM ceftriaxone followed by 14 day course of oral doxycycline
95
Name some physical exam findings for allergic rhinitis.
Pale bogy turbinates, allergic shiners, allergic salute.
96
Treatment for allergic rhinitis?
Intranasal corticosteroid, second generation antihistamines
97
Vasomotor rhinitis, a common cause of clear rhinorrhea in older patients, is associated with an increased sensitivity of which nerve?
The vidian nerve.
98
Lab findings in allergic rhinitis?
Elevated serum IgE
99
What is Samters triad?
Nasal polyps, asthma, and aspirin sensitivity.
100
Describe the typical patient with immune thrombocytopenia (idiopathic thombocytogenic purpura).
2-5 year old with history of a recent viral infection.
101
Lab findings in ITP patient?
Platelets <100k (but not uncommon to see below <30k) | Normal hemoglobin, hematocrit, and WBC count.
102
Treatment for severe ITP includes?
Platelets, glucocorticoids, IVIG
103
How long does resolution of ITP typically take?
3-6 months
104
When can ITP patients be managed outpatient?
If they do not need rapid elevation in platelets, and if bleeding is limited to mild cutaneous bleeding.
105
Name a common neurologic finding associated with vitamin B12 deficiency anemia.
Gait ataxia
106
What peripheral blood smear finding is common in Vit B12 deficiency anemia?
Hypersegmented neutrophils.
107
What labs can help differentiate between a Vit B12 deficiency and folate deficiency?
Methylmalonic acid and homocysteine. | Elevated indicates B12 deficiency, normal indicated folate deficiency.
108
What is an appropriate regimen to correct a B12 deficiency?
1,000 mcg injection of B12 once a week until corrected, then once a month
109
What skin finding can be noted in severe iron deficiency anemia?
Chlorosis (pale green discoloration)
110
What nail finding is expected in iron deficiency anemia?
Koilonychia (spoon nails)
111
What is a physical exam finding that can help you differentiate between B12 and folate deficiency anemia?
Folate deficiency can present with oral ulcers. | B12 can present with neuropathy.
112
Name some causes of B12 deficiency.
Veganism, metformin, conditions affecting nutrient absorption (Chron's)
113
When a patient presents with a fib, it is important to rule out reversible causes such as ____ and _____.
Thyroid disorders and diabetes mellitus
114
List the components of CHA2DS2-VASc
``` CHF HTN Age (64-74=1. >75=2_ DM Stroke TIA or VTE ```
115
Which of the following oral antifungals is no longer recommended as first-line oral treatment due to the risk of drug-induced hepatitis?
Ketoconazole.
116
What organism is the most common cause of tinea versicolor?
Malassezia species
117
Treatment for tinea versicolor?
Selenium sulfide
118
First line treatment for hypertension in black patients?
Thiazide like diuretic or long-acting dihydropyridine CCB
119
First line treatment for hypertension in young patients?
ACEIs, ARBs, (Beta blokcers if they have other conditions that would benefit)
120
First line treatment for hypertension in old patients?
Thiazide-like diuretic or long-acting CCB
121
What type of hypertension can be treated with lifestyle modifications?
Primary hypertension (resulting from multiple genetic and environmental factors including age, obesity, high-sodium diet, and physical inactivity)
122
Name 3 common manifestations of SLE.
Malar rash sparing nasolabial folds Raynaud phenomenon Photosensitivity (these were the bolded ones in rosh, I know theres a lot)
123
What lab tests have high specificity for SLE?
Anti-double-stranded DNA | anti-Smith antibodies
124
Can patients with SLE receive vaccines?
Only before starting immunosuppressive therapies.
125
An SLE patient comes into primary care for pre-conception counseling. What do you make sure to advise her of?
She should avoid pregnancy for 6 months after active diesase.
126
Which antibody is associated with drug-induced lupus erythematosus?
Antihistone antibody.
127
At what location is the murmur for aortic regurgitation heard?
Left upper sternal border
128
Symptoms of aortic regurgitation?
Exertional dyspnea, hyperdynamic apical pulse, wide pulse pressure.
129
What does the murmur of aortic regurgitation sound like?
Acute - low pitched, early diastolic murmur | Chronic - high-pitched, holodiastolic murmur
130
What should a aortic regurgitation murmur do when the patient preforms a Valsalva maneuver?
Decrease in intensity
131
The initial imaging test of choice for aortic regurgitation is?
Transthoracic echocardiogram
132
What is the definitive management for aortic regurgitation?
Surgical repair or replacement
133
What is the most common cause of aortic regurgitation?
Endocarditis
134
What medication should a patient be started on after a aortic valve replacement?
warfarin
135
What is the goal INR for a valve replacement patient?
2.5-3.5
136
What is an Austin Flint murmur?
A late diastolic murmur best heard at the apex. The sound heard is due to retrograde blood flow competing with antegrade flow from the left atrium.
137
What is Duroziez sign? | What is it a sign of?
A systolic and/or diastolic thrill or murmur heard over the femoral arteries. It is a sign of aortic regurgitation
138
What type of airway disease is asthma?
Obstructive
139
What do you expect FEV1 and FVC to be in asthma?
Increased FEV1 and decrease FVC.
140
What is the FEV1/FVC ratio expected in obstructive airway conditions?
<0.70
141
Treatment for intermitent asthma?
SABA PRN
142
Treatment for mild persistent asthma?
SABA + low dose ICS
143
Treatment for moderate persistent asthma?
LABA + low dose ICS
144
Treatment for severe persistent asthma?
LABA + medium dose ICS
145
Which class of medication is montelukast?
Leukotriene inhibitor.
146
Name some medications that can cause erosive esophagitis?
``` NSAIDs Bisphosphonates Potassium Chloride Quinidine Vit C ```
147
Symptoms of erosive esophagitis?
Dysphagia, odynophagia, retrosternal chest pain
148
In a patient with esophagitis, what red flags would make you want to perform an upper endoscopy?
Hematemesis, abd pain, weight loss, persistent symptoms after discontinuation of medication
149
What measures can be taken to prevent esophagitis caused by medications?
Standing upright for 30 minutes after taking medication, eating meal after taking the medication, taking the medication with at least 8oz water.
150
What is the first-line treatment for benign esophageal strictures?
Esophageal dilation.
151
What is the diagnostic criteria for chronic insomnia?
Difficulty falling or staying asleep at least 3 times a week for > 3 months
152
What is the preferred first-line treatment for insomnia?
CBT
153
What are some pharmacologic treatments for insomnia?
Benzos | Non-benzo receptor agonists (Z drugs)
154
What are the two most common relaxation-based strategies used for insomnia disorder?
Progressive muscle relaxation and diaphragmatic breathing.
155
What lab values are abnormal in irritable bowel syndrome?
none
156
What type of diet can be beneficial for IBS?
FODMAP | Fermentable Oligosaccharides, Disaccharides, Monosaccharides And Polyols
157
First line treatment for abdominal pain in IBS?
Antispasmodics such as dicyclomine of hyoscyamine.
158
Which COPD therapy has been shown to improve survival?
Long-term continuous oxygen therapy.
159
What are the two most common risk factors for CAD?
HTN and DM
160
What two diagnostics are important in the evaluation of CAD?
Cardiac enzymes and EKG
161
A lesion in which vessel is indicated by ST elevations in leads V1, V2, V3, and V4?
Left anterior descending (LAD).
162
What is the cause of diabetes mellitus type 1?
Pancreatic islet B cell destruction which is primarily autoimmune.
163
Describe the typical age of a patient at time of diagnosis of DM 1
Child to young adult
164
What is the cause of diabetes mellitus type 2?
Pancreatic beta cell dysfunction combined with insulin resistance.
165
When is DM II usually diagnosed?
Predominantly occurs in adults.
166
What is the most important environmental factor causing insulin resistance?
Obesity.
167
Symptoms of DM I?
Polyuria, polydipsia, weight loss with normal appetite. | Patients may have muscles wasting and weakness, paresthesias, and peripheral neuropathy.
168
Symptoms of DM II?
Typically asymptomatic because progression is slow.
169
Name 1 skin finding associated with insulin resistance.
Acanthosis nigricans
170
What is the criteria for diagnosing diabetes?
Random plasma glucose >200 in a symptomatic pt Fasting plasma glucose >126 on two sperate occasions. Glucose level >200 2 hours post oral glucose tolerance test. H1C >6.5%
171
What type of obesity is associated with insulin insensitivity?
Visceral obesity due to the accumulation of fat in the omental and mesenteric regions.
172
An acute gout attack should be treated with?
NSAID such as indomethacin
173
Name some medications that increase risk for hyperuricemia.
Diuretics, thiazides, aspirin, cyclosporine, niacin.
174
Name 2 dietary risk factors for gout.
Excessive alcohol ingestion (particularly beer) and a high-purine diet.
175
What joint is most commonly affected by gout?
The MTP of the great toe
176
The definitive diagnosis of gout is made by?
Joint fluid aspirate showing Negatively birefringent needle shaped sodium urate crystals.
177
What x ray finding is expected in chronic gout?
Rat bite erosions
178
What medications reduce the risk of recurrence of gout and what is their mechanism?
Allopurinol - decreases production of uric acid | Colchicine and probenecid increase urinary excretion of uric acid.
179
What diagnosis are positively birefringent, rhomboid-shaped crystals in synovial fluid consistent with?
Pseudogout, also known as calcium pyrophosphate deposition.
180
What are the most common side effects of metformin?
Nausea, vomiting, diarrhea, flatulence, abd cramping.
181
What is the mechanism of action of saxagliptin?
Saxagliptin is a dipeptidyl peptidase-4 inhibitor that prolongs incretin levels and decreases glucagon secretion.
182
Describe the genetic mutation known as the Philadelphia chomosome.
Reciprocal translocation on the long arms of chromosomes 9 and 22
183
What disorder is caused by the Philadelphia chromosome?
Chronic myelogenous leukemia
184
What is the age range that patients begin to develop symptoms of CML?
40-60
185
What are the symptoms of CML?
splenomegaly, fever, night sweats, and weight loss
186
Lab findings in CML?
Increased WBC count | Peripheral blood smear shows greater percentage of blast cells.
187
Treatment for CML?
Allogenic hematopoietic cell transplantation
188
What is the most common childhood leukemia?
Acute lymphocytic leukemia
189
Auer rods are seen in what type of leukemia?
Acute myelogenous leukemia
190
What is the most common adult leukemia?
Chronic lymphocytic leukemia
191
Smudge cells are seen in what type of leukemia?
Chronic lymphocytic leukemia
192
What disease causes non-caseating granulomas forming throughout the body?
Sarcoidosis
193
What two organs are most commonly affected by sarcoidosis?
Skin and lungs
194
Describe skin findings of sarcoidosis.
Erythematous, painful, warm patches and nodules that appear on the shins, arms, and buttocks.
195
What is the name of the rash caused by sarcoidosis?
Erythema nodosum
196
What are the chest x ray findings on a typical sarcoidosis patient?
Bilateral hilar adenopathy
197
Diagnostic test of choice for sarcoidosis?
Transbronchial lung bopsy
198
On what test are lambda and panda signs seen?
Gallium scintigraphy
199
What abnormal bloodwork is present in sarcoidosis?
Hypercalcemia and elevated serum ACE, ESR and CRP elevated.
200
Treatment for sarcoidosis?
steroids
201
When does symptom onset for parkinsons typically occur?
45-65 years
202
Name the common clinical manifestations of parkinsons.
Resting or pill-rolling tremor, cogwheel or lead pipe rigidity, bradykinesia, postural instability, masked facies.
203
What is dysdiadochokinesia?
Loss of ability to preform rapid alternating movements.
204
What is the mainstay of treatment of parkinsons for patients >65?
Levodopa carbidopa
205
What is the treatment of parkinsons for patients <65?
Dopamine agonists such as pramipexole, ropinirole, and bromocriptine
206
What sign seen in Parkinson disease is characterized by a sustained blink response to repetitive tapping over the bridge of the nose?
Myerson sign.
207
What is the most common bacterial cause of perotitis?
Staph aureus
208
Parotitis is particularly common in what patient population?
Elderly post op patients
209
Do parotitis patients need to be admited?
Yes, they need IV antibiotics because infection can spread to the deep fascial p
210
What culture should be preformed for parotitis patients?
Gram stain and culture of the Stensen duct
211
What are the empiric antibiotic recommendations for community acquired vs. hospital acquired parotitis?
Community acquired - ampicillin-sulbactam or cefuroxime + metronidazole Hospital acquired - either vancomycin or linezolid plus one of the following (cefepime and metronidazole) (imipenem) (meropenem) (piperacillin tazobactam)
212
What are the risk factors for methicillin-resistant Staphylococcus aureus?
Intravenous drug use, residence in a long-term care facility, discharge from a hospital within the preceding 12 months, and hemodialysis.
213
Describe the rash caused by cellulitis.
Single, painful, erythematous patch with poorly demarcated borders and overlying warmth
214
What rash is described as multiple lesions with three concentric zones of color change?
Erythema multiforme
215
What rash is described as purple, pruritic, polygonal, planar, papular plaques?
Lichen planus
216
What rash is described as raised, purpuric, target-like lesions with two zones of color change?
Stevens-Johnson syndrome and toxic epidermal necrolysis.
217
What form of cellulitis is characterized by a bright red plaque with raised and sharply demarcated borders?
Erysipelas
218
What is the only antianginal agent proven to improve mortality in patients with CAD?
Beta blockers
219
Which reflex originates in the cardiac sensory receptors and promotes parasympathetic activity, resulting in bradycardia, vasodilation, and hypotension?
The Bezold-Jarisch reflex
220
What is the single most common cause of acute bacterial sinusitis?
Strep pneumo
221
What is the most common bacteria causing chronic sinusitis?
Staph aureus
222
What is a major side effect of pseudoephedrine, especially if used for more than 3 days?
Rhinitis medicamentosa | rebound congestion
223
What is the most sensitive test used to diagnose inflenza?
Reverse transcriptase PCR
224
Antiviral therapy may be considered in which influenza patients?
Patients with severe influenza, those at risk for complications, and those not at high risk who present with 48 hours of onset of illness
225
What medication is used to treat influenza?
Oseltamivir
226
What is the most common complication of influenza?
pneumonia
227
What is the initial treatment for frozen shoulder.
Initially treat with PT | +/- steroid injections
228
What is the treatment for frozen shoulder that persists past 10-12 months?
Manipulation under anesthesia or arthroscopic surgical release.
229
What two movements of the shoulder are most commonly affected by frozen shoulder?
External rotation and abduction
230
What nerve passes through the quadrangular space of the shoulder?
The axillary nerve.
231
What virus is responsible for warts?
Human papillomaviruses
232
Treatment for nongenital warts?
Liquid nitrogen cryotherapy or salicylic acid plaster after paring
233
Treatment for genital warts?
Liquid nitrogen cryotherapy, podophyllum resin, imiquimod 5% cream, excision and electrocautery, and laser therapy
234
Which two human papillomavirus types are most commonly associated with condyloma acuminata?
Human papillomavirus types 6 and 11.
235
What are the black dots that appear within warts?
Thrombosed capillaries
236
What is a positive murphy sign?
Pain and cessation of breathing upon palpation in the area of the gallbladder fossa while the patient is taking a deep breath.
237
What condition is defined as inflammation of the gallbladder as a result of cystic duct obstruction?
Cholecystitis.
238
What is the initial choice of imaging for a suspected cholecystitis?
Ultrasound
239
What ultrasound findings correlate with the diagnosis of cholecystitis?
Presence of stones, gallbladder wall thickening, or pericholecystic fluid.
240
What is the preferred definitive treatment for cholecystitis?
Cholecystectomy.
241
What is Charcot triad?
Jaundice, fever, and right upper quadrant abdominal pain.
242
What is the gold standard imaging for suspected cholecystitis?
HIDA scan
243
An upright Xray, CT scan, or MRI showing a retrocardiac air-fluid level is diagnostic of what condition?
Hiatal hernia
244
What is a type I hiatal hernia, and what are they associated with?
Type I is a sliding hernia, and it is associated with trauma, congenital malformations, and iatrogenic factors.
245
Type II, III, and IV hiatal hernias are known as what type of hernias?
Paraesophageal hernias
246
What are paraoesophageal hernias associated with?
Surgical procedures.
247
Treatment of hiatal hernias?
Usually just involved management of GERD symptoms. | Surgical repair reserved for symptomatic patients.
248
What is the most commonly performed surgical procedure to correct a hiatal hernia?
Nissen fundoplication.
249
What is the most common cause of bronchitis?
Viruses (influenza, coronavirus, and rhinovirus are most common)
250
How long does the cough associated with bronchitis typically last?
Up to 3 weeks
251
Treatment for bronchitis?
Throat lozenges, hot tea, honey, smoking cessation.
252
What is the name of the pulmonary physical exam test performed by placing the ulnar aspects of both hands against the patient’s chest while the patient says the number 99?
Tactile fremitus.
253
What is the triad of symptoms associated with bulimia nervosa?
Caloric restriction, binge eating, and self-induced vomiting.
254
List some comorbid conditions associated with bulimia nervosa.
Unipolar depression and specific phobia disorder are the two most common
255
What emetic is often misused by patients with bulimia nervosa?
Syrup of ipecac.
256
Mild to moderate non-throbbing headache that is bilateral with pain in the frontal and occipital region describes what type of headache?
Tension headache
257
What are common associated symptoms with tension headaches?
Photophobia or phonophobia.
258
Treatment for tension headaches?
NSAIDs or aspirin
259
What is the first line preventative treatment for tension headaches?
Amytriptyline
260
What is the first-line acute treatment for cluster headache?
100% oxygen.
261
What are the two most common pathogens for otitis media?
H flu and Strep pneumo
262
AOM is most common in what age range?
6-24 months
263
What is the first line antibiotic for AOM? | What if they've had a beta lactam in the past 30 days?
Amoxicillin | Amox-clav if recent beta lactam use
264
Which antibiotics can be used to treat acute otitis media in children with anaphylactic reactions to amoxicillin?
Azithromycin or clindamycin.
265
Pyelonephritis with struvite stones is associated with what bacteria?
Proteus mirabilis and other urease producing bacteria
266
What is the most common pathogen of pyelonephritis?
E. coli
267
What is the empiric outpatient therapy for pyelonephritis?
1g ceftriaxone + one of the following: (trimethoprime-sulfamethoxazole) (amox-clav) (a cephalosporin) (a fluoroquinalone)
268
Inpatient empiric treatment for pyelonephritis?
Antipseucomonal carbapenem and vancomycin
269
How many colony-forming units of a single organism on urine culture are suggestive of a urinary tract infection?
10^5 | 100,000
270
What is the most common cause of heel pain in the US?
Plantar fasciitis
271
Treatment for plantar fasciitis?
ice, stretching, and rest | NSAIDs, acetaminophen, and orthotics may also be appropriate.
272
What Xray finding may be seen in plantar fasciitis?
Calcaneal spurs
273
What medical term is used to describe the pain that occurs after a period of rest and is associated with plantar fasciitis?
Poststatic dyskinesia.
274
What is Löfgren syndrome?
Combination of erythema nodosum, hilar adenopathy, migratory polyarthralgia, and fever observed in patients with sarcoidosis.
275
A small, round to oval ulcer with peripheral erythema and yellowish central exudate in the mouth describes the appearance of?
An aphthous ulcer (aphthous stomatitis)
276
Complex aphthosis is characterized by the presence of lesions where?
In the mouth AND geneital mucosa
277
Patients with complex aphthosis should be tested for?
Behçet syndrome
278
Patients with Behçet syndrome will have a postive ______ test.
Pathergy
279
Treatment for simple apthosis?
2% viscous lidocaine for analgesia and topical steroids at onset of symptoms
280
Which virus causes a flesh-colored, cauliflower-like genital lesion?
Human papillomavirus.
281
Treatment for Torsades?
Defib if hypotensive and mag sulfate.
282
Name 4 classes of laxatives and give and example of each.
Stimulant laxatives -biscodyl Osmotic laxatives - sorbitol Surfactant laxatives - docusate Bulk Forming laxatives - psyllium, methylcellulose
283
What are the possible adverse effects of using sodium phosphate enemas in older adults?
Volume depletion, hypotension, hyperphosphatemia, hypokalemia, hyperkalemia, metabolic acidosis, and acute kidney injury.
284
What are the risk factors for sleep apnea. Be specific.
BMI >29 Neck circumference > 17 in men and >16 in women Crowded oropharyngeal airway Waist:Height >100.4cm for men and 95.5 for women
285
What is the gold standard test for sleep apnea?
In-laboratory polysomnography
286
What indicates a positive polysomnography test?
five or more obstructive respiratory events/hour
287
The mainstay of treatment for sleep apnea is?
CPAP
288
What is Cheyne-Stokes breathing?
An abnormal pattern of breathing characterized by periods of tachypnea and hyperpnea alternated by periods of apnea.
289
What is the first line treatment for an essential tremor?
Propanolol
290
What is the most common isolated focal dystonia?
Cervical dystonia.
291
First line treatment for Bipolar disorder?
Quetiapine or lursidone
292
What is the first-line treatment for bipolar disorder in pregnant patients?
Lamotrigine.
293
What is the typical number of leads on a traditional Holter monitor?
Three (although 12-lead monitors are available).
294
In long term untreated carpal tunnel syndrome, is thenar atrophy or hypothenar atrophy seen?
Thenar atrophy
295
What physical exam testing is associated with carpal tunnel syndrome?
Tinel sign and Phalen sign
296
List 3 risk factors for carpal tunnel syndrome?
Female sex, pregnancy, diabetes.
297
What is the first line treatment for carpal tunnel syndrome?
Night splints, NSAIDs, physical therapy, exercise, stretching.
298
What is the definitive therapy for carpal tunnel syndrome?
Surgical decompression.
299
When is Chvostek's sign positive?
Hypocalcemia
300
A positive Adson test is indicative of?
Thoracic outlet syndrome
301
How many tendons are located within the carpal tunnel?
Nine.
302
Carpal tunnel syndrome is most commonly caused by the compression of what nerve?
Median nerve
303
Addison disease is most commonly caused by?
Autoimmune dysfunction
304
What hormones are chronically elevated in Addison disease?
ACTH and melanocyte stimulating hormones
305
Symptoms of Addison disease?
Abd pain, nausea, vomitting, diarrhea, confusion, Fatigue, weakness, weight loss, salt craving, hypotension.
306
Lab findings in Addison disease?
Hyponatremia and Hyperkalemia
307
What tests are indicative of primary adrenal insufficiency?
Cosyntropin stimulation test or corticotropin-releasing` hormone stimulation test
308
Treatment for Addison disease?
Corticosteroid replacement therapy with hydrocortisone and mineralocorticoid replacement therapy with fludrocortisone.
309
What test is used to diagnose Cushing syndrome?
Dexamethasone suppression test.
310
Which androgen is androstenedione converted into?
Testosterone
311
A warm, edematous, exquisitely tender prostate are signs of?
Prostatitis
312
What is the most common pathogen of prostatitis?
E. coli
313
Inpatient management of prostatitis?
IV ampicillin and aminoglycoside (gentamycin)
314
Outpatient treatment for prostatitis?
6 week course of oral antibiotics (trimethoprim-sulfa, ciprofloxacin)
315
What class of medications is recommended as the initial treatment for symptomatic benign prostatic hyperplasia?
Alpha-1 adrenergic antagonists (e.g., tamsulosin, terazosin).
316
Initial diagnostic approach for CHF?
EKG, Chest XR.
317
What is the most commonly used diagnostic study for CHF?
Echocardiography
318
What is the gold standard diagnostic for CHF?
Right heart catheterization
319
Therapy for CHF?
Decreasing sodium intake, ACEI, diuretic, and beta blockers
320
What is the name of the horizontal lines on a chest radiograph resulting from interstitial edema that may be seen in heart failure patients?
Kerley B lines.
321
List the symptoms of retina detachment.
painless loss of vision, floaters, flashing lights, curtain lowering sensation
322
What is the most common cause of epididymitis in patients younger than 35 years old?
Chlamydia trachomatis | Neisseria gonorrhoeae is 2nd
323
What is a positive Prehn sign?
Relief of pain with support of the testicle.
324
Treatment for epididymitis for patients younger than 35? | Older than 35?
Younger - ceftriaxone 250mg IM once + doxycycline 100mg BID x 10 days Older - levofloxacin 500mg QD x 10 days
325
Epididymitis in patients who participate in anal sex should be treated with?
Ceftriaxone and levofloxacin
326
What diagnosis is the blue dot sign associated with?
Torsion of the appendix of the testicle.
327
List the symptoms of Meniere's disease.
Episodic vertigo, tinnitus, and low-frequency sensorineural hearing loss
328
Are symptoms typically unilateral or bilateral in Meniere's disease?
Unilateral
329
What dietary restrictions can you give to a patient to improve Meniere's disease?
Limit sodium, caffeine, alcohol, nicotine, and MSG.
330
Pharmacologic treatment for Meniere's disease consists of?
A diuretic or chronic betahistine +/- a benzodiazepine
331
Which disorder is characterized by progressive unilateral sensorineural hearing loss, disequilibrium, and facial numbness secondary to compression of the vestibulocochlear nerve?
Vestibular schwannoma, also known as acoustic neuroma
332
``` Which of the following types of lung cancers is less likely associated with smoking? A. Adenocarcinoma B. Large cell carcinoma C. Small cell carcinoma D. Squamous cell carcinoma ```
Adenocarcinoma
333
What is the most common type of breast cancer?
Invasive ductal carcinoma
334
What is the classic presentation of breast cancer?
A hard immobile breast mass.
335
Diagnosis of breast cancer is made by?
Biopsy of breast tissue with malignant cells.
336
What are two factors that may reduce breast cancer risk?
Breastfeeding and increased regular physical activity.
337
What is the most common pathogen responsible for infective endocarditis.
Staph aureus
338
List the classic signs of infective endocarditis.
Cardiac murmur Petechiae Spinter hemorrhages Janeway lesions (painless lesions on palms and soles) Osler nodes (painful lesions on fingers, toes, or feet) Roth spots (lesions on retina)
339
What is the diagnostic of choice for endocarditis?
Echocardiogram
340
What criteria are used to diagnose endocarditis?
Duke criteria
341
How many criteria must be positive to diagnose a patient with endocarditis using Duke criteria?
Two major One major and three minor Five minor
342
What are the major and minor criteria?
Major: + blood cultures, evidence of endocardial involvement Minor: IVDU, fever, vascular phenomena, immunologic phenomena, and microbiologic evidence.
343
Which heart valve is most affected by infective endocarditis in intravenous drug users?
Tricuspid valve.
344
What is the most common acute leukemia in adults?
AML
345
Peripheral blood smear in AML shows presence of ?
Auer rods
346
Diagnosis of AML is confirmed by?
Bone marrow biopsy
347
Bone marrow biopsy must show blast cells greater than ___% to diagnose AML.
20%
348
First line treatment for AML?
Combination chemotherapy most commonly with anthracycline and cytarabine in a 7+3 regimen
349
What are the metabolic abnormalities associated with tumor lysis syndrome?
Hyperphosphatemia, hypocalcemia, hyperuricemia, and hyperkalemia.
350
Give examples of two high intensity statin therapies.
Atorvastatin 40-80mg | Rosuvastatin 20-40mg
351
If a patient develops endocarditis within 2 months of a valve replacement, what are the most common organisms?
Staph aureus Gram negative bacilli Candida
352
If a patient develops endocarditis 2-12 months after a valve replacement, what is the most common organism?
Staph epidermidis
353
If a patient develops endocarditis greater than 12 months after a valve replacement, what is the most common organism?
Strep viridans or strep bovis
354
What organisms make up the HACEK group of organisms?
Haemophilus, Actinobacillus, Cardiobacterium, Eikenella, and Kingella.
355
What is a pancoast tumor?
A lung tumor (non-small cell is most common) that occurs in the superior sulcus causing dermatomal symptoms resulting from brachial plexus involvement.
356
What are the symptoms of a pancoast tumor?
Honer syndrome, ipsilateral ptosis and miosis, superior vena cava syndrome, muscle atrophy, weakness, and pain. Also the expected symptoms of lung cancer like cough, sob, hemoptysis ect.
357
What are the two phases of the menstrual cycle?
The follicular phase and the luteal phase.
358
During the beginning of the follicular phase, what are the serum estradiol and progesterone levels?
Low
359
Low levels of estradiol and progesterone stimulate the hypothalamus to ?
Release GnRH in pulses
360
Increased GnRH causes?
Release of FSH and LH from the anterior pituitary.
361
When do estradiol levels peak?
1 day before ovulation
362
What amount of blood loss during a menstrual cycle defines heavy menstrual bleeding?
> 80 mL.
363
Hallmark symptom of classic Hodgkin lymphoma?
Diffuse lymphadenopathy
364
Hodgkin lymphoma is most common in what age range?
15-35
365
Biopsy of a lymph node in hodgkin lymphoma will show?
Reed Sternberg cells (Bilobed nucleus that looks like an owls eyes.
366
True or false: eosinophilia is a common finding in Hodgkin lymphoma.
True. Increased production of chemokines induces eosinophilia.
367
What is the most common location for a ganglion cyst?
The dorsal aspect of the wrist over the scaphlunate joint
368
Do ganglion cysts transilluminate?
Yes
369
What is the initial treatment for a ganglion cyst?
Reassurance and waiting. 50% will resolve spontaneously
370
What is the definitive treatment for a ganglion cyst?
Surgical excision
371
What condition secondary to ligamentous injury is suspected when the Terry-Thomas sign is seen on wrist X-ray?
Scapholunate dissociation.
372
List physical exam findings in hypertrophic cardiomyopathy.
Pulsus bisferiens (biphasic pulse due to aortic regurgitation) Triple apical impulse S4 gallop
373
Does the murmur from hypertrophic cardiomyopathy increase of decrease with valsalva?
Increase
374
How is hypertrophic cardiomyopathy diagnosed?
Echocardiogram
375
Pharmacologic treatment for hypertrophic cardiomyopathy?
beta blocker or CCB to decrease myocardial contractility.
376
Which gallop heard on cardiac auscultation can be a normal finding in patients < 30 years of age?
S3 gallop.
377
What is the only FDA approved treatment for pain associated with fibrocystic breast disease?
Danazol
378
Breast pain in fibrocystic breast disease is caused by what?
Fluctuating estrogen levels during menstrual cycles.
379
When does breast pain and tenderness peak in fibrocystic breast disease?
before each mensuration
380
What is the name of the fibroadenoma-like tumor with cellular stroma that grows rapidly and has a leaf-like pattern on histology?
Phyllodes tumor.
381
What is more common, hyper or hypothyroidism?
Hypothyroidism.
382
What is the most common cause of hyperthyroidism?
Graves disease
383
What lab studies are diagnostic of hyperthyroidism?
A low TSH and a high T4
384
What is the most sensitive test for diagnosing graves disease?
Antithyrotropin receptor antibody test
385
What are the treatments of choice for graves diease?
Methimazole or PTU
386
Which antithyroid modulating drug is the drug of choice in pregnant women?
PTU
387
What is the treatment for graves disease in patients whose symptoms are not controlled by antithyroid modulating drugs?
Radioactive iodine ablation or thyroidectomy.
388
What are potential complications of untreated exophthalmos?
Corneal dryness and damage, keratoconjunctivitis, compression of the optic nerve or optic artery, and blindness.
389
What is the most common pathogen in septic bursitis?
Staph aureus
390
Will a patient with septic bursitis have full passive range of motion?
Yes - because the infection is isolated to the bursa. | Diminished ROM can be a sign of septic arthritis.
391
What is the gold standard for diagnosis of septic bursitis?
Bursa fluid culture
392
What is the outpatient treatment for septic bursitis with no concerns of MRSA?
Cephalexin or dicloxacillin. x 10 days
393
What is the outpatient treatment for septic bursitis with concerns of MRSA?
Trimethoprim-sulfamethoxazole x 10 days
394
True or false: aseptic bursitis can be caused by gout.
True.
395
What is a common but harmless side effect of taking the tuberculosis medication rifampin?
It can cause body fluids (urine, sweat, saliva, tears) to change color to yellow, orange, red, or brown.
396
If a patient has a positive PPD test, what is recomended next?
A confirmatory interferon-gamma release assy (IGRA)
397
What vaccine can cause a positive PPD?
bacillus Calmette-Guerin vaccination
398
Therapy for latent TB usually includes what two medications?
Rifampin or isoniazid (alone or together)
399
Does psoriasis typically affect flexor or extensor surfaces?
Extensor
400
What are some nail findings common is psoriasis?
Nail pitting and separation from the nailbed.
401
What is the Koebner phenomenon?
Plaque formation at the site of prior trauma developing 1-2 weeks after the injury.
402
What is the auspitz sign?
Punctate bleeding spots when scales are lifted. This is a finding of psoriasis.
403
What is the treatment for psoriasis if <10% BSA is involved.
High-potency to ultra-high-potency topical steroids.
404
T/F? Psoriatic arthritis flare ups should be treated with oral corticosteroids.
False - rebound effects are are severe
405
What is the treatment for psoriasis if 10%-30% BSA affected?
Ultraviolet phototherapy.
406
What is the treatment for psoriasis if >30% BSA affected?
Narrowband ultraviolet phototherapy, Psoralen plus UVA photochemotherapy, or systemic agents such as methotrexate or biologics.
407
The diagnosis of Cushing syndrome is made with what tests?
24 hour urine cortisol and ACTH levels
408
The diagnosis of cushing disease can be made with what test?
High-dose dexamethasone suppression test
409
What drugs increase the metabolism of dexamethasone leading to impaired cortisol suppression?
Antiseizure drugs (e.g., phenytoin, phenobarbital) and rifampin.
410
What is the most common cause of cushing syndrome?
Cushing disease - ACTH secreting pituitary tumor
411
How often should someone with normal risk for breast cancer be screened for breast cancer? What is the preferred screening modality?
Bilateral screening mammography every 2 years
412
How often should someone with high risk for breast cancer be screened for breast cancer? What is the preferred screening modality?
Annual breast MRIs
413
When is breast ultrasound used?
Patients younger than 30 presenting with a breast mass.
414
What is the preferred screening modality for an AAA?
Ultrasonography
415
Who should receive screening for AAA?
Men ages 65-75 who have ever smoked
416
What are the two greatest interventions to reduce the risk for developing an abdominal aortic aneurysm?
Smoking cessation and blood pressure control.
417
List the deformities you would expect to see in rheumatoid arthritis.
``` Ulnar deviation Swan neck deformity Boutonniere deformity Bow string sign Rheumatoid nodules ```
418
What joints are commonly affected by rhemuatoid arthritis?
MCPs, PIPs, MTPs, wrists, knees, and ankles
419
First line treatment for rheumatoid arthritis?
DMARDs such as methotrexate. | Low dose corticosteroids as bridge until DMARD starts working.
420
Pencil-in-cup deformity is seen in what disease?
Psoriatic arthritis.
421
How long does morning stiffness last in rheumatic arthritis?
>30 minutes
422
What are lab findings in RA?
Positive RF and anti-cyclic citrullinated peptide antibodies. (but you can also have seronegative RA)
423
What is the classic patient presentation of acute pancreatitis?
Epigastric pain radiating to back, nausea, and vomiting.
424
What physical exam findings are suggestive of pancreatitis?
Grey Turner sign (flank ecchymosis) and Cullen sign (umbilical eccymosis)
425
Most common cause of pancreatitis?
Gallstones, then alcohol
426
What labs are elevated in pancreatitis?
Lipase and amylase are most reliable | also BUN, leukocytes, glucose
427
What can be used to assess the severity of pancreatitis?
Ranson criteria
428
Treatment for pancreatitis?
Bowel rest, bed rest, IV fluids, and pain control
429
What gastrointestinal disorder is autoimmune pancreatitis commonly associated with?
Celiac disease.
430
List the hallmark of glaucoma on fundoscopy?
Optic disc cupping | Cup to disc ratio >0.5
431
What is considered an increased IOP?
>21 mm Hg
432
First line treatment for chronic glaucoma?
Prostaglandin analog such as latanoprost +/- Topical beta blocker such as timolol.
433
What procedure is standard for chronic open-angle glaucoma?
Trabeculectomy
434
What is the second line treatment for chronic gloaucoma?
Alpha 2 agonists such as brimonidine or carbonic anhydrase inhibitors such as acetazolamide
435
What surgical procedure is used as definitive treatment for angle-closure glaucoma?
Peripheral iridotomy.
436
What is the antibiotic of choice for patients with corneal abrasion?
Erythromycin ointment for non-contact lens wearers | Fluoroquinolone or aminoglycoside drops from contact lens wearers for pseudomonas coverage.
437
Which screening test for corneal disorders is used to evaluate for the presence of anterior chamber leakage into the cornea?
Seidel test.
438
True or false: montelukast is effective in treating exercise-induced asthma.
True.
439
Does mononucleosis cause anterior or posterior cervical chain lymphadenopathy?
Posterior
440
How is labyrinthitis distinguished from vestibular neuritis?
Labyrinthitis involves inflammation of the cochlear part of the vestibulocochlear nerve causing hearing loss and tinnitus.
441
Causes of labyrinthitis?
Viruses such as herpes simplex, varicella-zoster, and epstein-barr.
442
What are the symptoms of labyrinthitis?
Hearing loss, tinnitus, PERSISTENT vertigo (as compared to intermitent in BPPV), horizontal nystagmus.
443
What is the treatment of vestibular neuritis?
Corticosteroids (prednisone) | Antihistamines, benzodiazepines, and antiemetics can also be used for symptomatic treatment.
444
What are the absolute contraindications to administering alteplase in the treatment of an acute ischemic stroke?
Intracranial hemorrhage on CT; neurosurgery, head trauma, or stroke within the past 3 months; uncontrolled hypertension (> 185/110 mm Hg); history of intracranial hemorrhage; known arteriovenous malformation, aneurysm, or neoplasm; suspected or confirmed endocarditis; known bleeding diathesis; and glucose < 50 mg/dL.
445
What maneuver is used to diagnose BPPV? | What maneuver is used to treat it?
Dix-halpike is the diagnosing maneuver | Epley maneuver is used to treat it.
446
What is the initial test of choice for gonorrhea?
nucleic acid amplification testing of first-catch urine or urethral swab in men, or a vaginal or endocervical swab in women.
447
What is the preferred antibiotic regimen for urethritis?
Ceftriaxone 500mg IM once and Doxycycline 100mg BID x 7 days
448
What inflammatory syndrome involving the Glisson capsule can occur in patients with pelvic inflammatory disease secondary to Chlamydia trachomatis and Neisseria gonorrhoeae?
Fitz-Hugh-Curtis syndrome
449
What is the preferred antibiotic regimen in patients with chlamydia urethritis who have had a Gonorrhea infection ruled out?
Doxycycline 100mg BID x 7 days
450
What is a common arrhythmia in patients with anorexia nervosa?
Sinus bradycardia
451
What antidepressant should be avoided in patients with eating disorders?
Bupropion, due to lowering of the seizure threshold. | Seizures can occur in patients with eating disorders due to hypoglycemia
452
What is the expected FEV1/FVC ratio in COPD?
Decreased
453
What are the 3 subtypes of COPD?
Emphysema, chronic bronchitis, and chronic obstructive asthma
454
What is the treatment for COPD?
inhaled bronchodilators, oxygen, and pulmonary rehabilitation.
455
Which hereditary disorder should patients with suspected COPD be evaluated for?
Alpha-1 antitrypsin deficiency.
456
Which patients are known as pink puffers and which are known as blue bloaters?
Pink Puffer emPhysema | Blue Bloater Bronchitis
457
Signs of retinal artery occlusion on fundoscopy?
Retinal pallor, cherry red fovea,
458
Is retinal artery occlusion painless or painful?
Painless
459
In a patient over 50 in whom you suspect CRAO, what must you rule out and how do you rule it out?
Giant cell arteritis with ESR
460
Vision may be spared if an retinal artery embolus can be removed within what time frame?
100 minutes
461
Treatment for CRAO?
Ophthalmology STAT and ocular massage
462
Name 3 rashes that can occur on the palms and soles of the feet.
Erythema multiforme Coxsackie virus Secondary syphilis
463
Describe the rash of erythema multiforme.
Raised blanching target shaped lesions with 3 concentric zones of color change.
464
Erythema multiforme is associated with what virus?
Herpes simplex virus | The rash is caused by a type IV herpsensitivity reachion.
465
Describe the rash associated with secondary syphilis.
Diffuse symmetric macular or papular rash affecting the trunk as well as the extremities including the palms and soles.
466
What is the treatment for erythema multiforme?
Oral antihistamines or low potency topical steroids.
467
What drugs can cause erythema multiforme?
SOAPS | Sulfa, Oral hypoglycemic, Anticonvulsants, Penicillin, nSAIDs
468
Describe the murmur of mitral valve prolapse.
Midsystolic click that increases with valsalvaa.
469
Mitral valve prolapse is diagnosed by?
Echocardiography.
470
Treatment for mitral valve prolapse?
Lifestyle modifications such as increasing aerobic exercise, decreased caffeine and alcohol intake, and reducing stress.
471
Which valvular disorder is associated with an Austin Flint murmur?
Aortic regurgitation.
472
What is an Austin Flint murmur?
a low-pitched rumbling heart murmur which is best heard at the cardiac apex
473
What is a positive Dix-Hallpike maneuver?
Vertigo beginning within 30 seconds and resolving within 30 seconds of preforming the maneuver.
474
What is canalithiasis?
Calcium debris in the semicircular canal.
475
An ABI below __ is diagnostic of PAD.
0.9
476
What is the gold standard for diagnosis of PAD?
Arteriography.
477
An ABI of <0.4 is diagnostic of what?
Critical limb ischemia
478
What is the pharmacologic treatment for PAD?
Cilostazol.
479
What is the most common artery involved in PAD?
The superficial femoral artery
480
What is the definitive treatment for severe PAD?
Revascularization via percutaneous transluminal angioplasty or bypass
481
Name the likely bacteria for each of the following sputum descriptions: Red currant-jelly sputum Green Sputum Rust colored sputum
Red currant-jelly sputum - Kelbsiella pneumo Green Sputum - haemophilus influenza or pseudomonas Rust colored sputum - Strep pneumo
482
What physical exam findings suggest lobar consolidation?
egophony, whispered pectoriloquy, and tactile fremitus.
483
What tool is used to determine if a patient with pneumonia should be admitted?
CURB65 score
484
What are the components of a curb 65 score?
``` Confusion Urea >7 RR > 30 SBP <90 age >65 Each is worth 1 point ```
485
A CURB65 of ___ or higher needs admission.
3
486
What is the preferred treatment for pneumonia caused by strep pneumo
Penicillin G or amoxicillin
487
Pneumonia caused by what organism leads to bradycardia rather than tachycardia?
Legionella pneumophila
488
Which pathogen is responsible for pneumonia with mild symptoms and is commonly called walking pneumonia?
Mycoplasma pneumoniae.
489
What are a patients expected thyroid labs in graves disease?
Decreased TSH, increased T3 and T4.
490
What is the most common cause of hypothyroidism?
Hashimoto thyroiditis.
491
What is a Monteggia fracture?
A proximal to mid unla fracture with radial head dislocation.
492
What is a Galeazzi fracture?
A distal radius fracture with distal radioulnar joint dislocation
493
What is a Maisonneuve fracture?
Fracture of the proximal fibular and a tear of the tibiofibular sysdesmosis.
494
What is a Smith fracture?
A fracture of the distal radius with volar angulation.
495
What is the mechanism of injury for a Maisonneuve fracture?
External rotation of the foot relative to the tibia.
496
What is the mechanism of injury for a Smith fracture?
Fall onto a flexed wrist of direct blow to the dorsal forearm
497
What is the name of the radiographic finding that describes the metaphyseal triangular portion in a Salter II fracture?
Thurstan Holland fragment.
498
What medication has been shown to reduce suicide risk in depressed patients?
Lithium.
499
What is the most common pathogen in atypical pneumonia?
Mycoplasma pneumoniae
500
What clinical features distinguish atypical pneumonia from typical pneumonia?
Insidious onset of dry cough
501
What is the treatment for atypical pneumonia?
Macrolides or doxycycline.
502
What are the signs of trichomoniasis?
frothy greenish yellow thin discharge, strawberry cervix, pH >5.0.
503
Describe the wet mount findings of trichomoniasis.
Flagellated motile trichomonads.
504
Which test can be used to confirm the diagnosis of trichomoniasis?
Nucleic acid amplification testing.
505
What is the definitive diagnosis for Alheimer disease?
Brain biopsy.
506
What are the histopathologic findings indicative of Alzheimer disease?
Amyloid plaques, accumulation of hyperphosphorylated tau protein in neurofibrillary tangles.
507
Accumulation of Negri bodies in the hippocampus is associated what what disease?
Rabies.
508
What is finger agnosia?
The loss of the ability to recognize one’s own fingers, the fingers of others, and any drawing or representation of fingers.
509
Treatment for Alzheime disease?
Cholinesterase inhibitors such as donepezil or NMDA antagonists such as memantine