Adrenergic Agonists Flashcards
What receptors do the following drugs act on? Epinephrine Norepinephrine Isoproterenol Albuterol Phenylephrine Dobutamine
Epinephrine - A1, A2, B1, B2 Norepinephrine - A1, A2, B1 Isoproterenol - B1, B2 Albuterol - B2 Phenylephrine - A1 Dobutamine - B1
What other drugs are Adrenergic agonists that do not act directly on a receptor?
Pseudoephedrine
Dopamine
Effect of adrenergic agonists on the heart?
What receptor is acted on?
Increase heart rate and contractility
Beta 1 receptors
Effect of adrenergic agonists on blood vessels?
What receptor is acted on?
Vasoconstriction - alpha 1
Vasodilation - Beta 2
Effect of adrenergic agonists on blood pressure?
What receptor is acted on?
Increase blood pressure - Alpha 1, Beta 1
Decrease blood pressure - Beta 2 (if unopposed by alpha 1)
Effect of adrenergic agonists on the lungs?
What receptor is acted on?
Bronchodilation - beta 2
Effect of adrenergic agonists on the eyes?
What receptor is acted on?
Mydriasis - alpha 1
Increase aqueous humor production (increase IOP) - Beta receptors
Effect of adrenergic agonists on the GI/GU system?
What receptor is acted on?
Detrusor muscle contraction - beta 2 and beta 3(??)
Close sphincter - alpha 1
Uterine relaxation - beta 2
Effect of adrenergic agonists on the CNS?
What receptor is acted on?
Increased vigilance and focus - alpha 1
Effect of adrenergic agonists on the NMJ?
What receptor is acted on?
muscle tremors - beta 2
