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Infectious Disease > I: STDs > Flashcards

I: STDs Flashcards

1
Q

____ are cell proliferation and transformation proteins in HPV, degrading p53 and inactivating pRB respectively.

A

E6, E7

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2
Q

____ are the infectious form of chlamydia.

A

Elementary bodies

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3
Q

____ are the vegtative form of chlamydia that multiplies intracellularly

A

Reticulate bodies

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4
Q

_____ are the major and minor capsid protein in HPV.

A

L1, L2

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5
Q

Chlamydia is lacking _____ in its cell wall

A

N-acetylmuramic acid

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6
Q

Gram stain of Neisseria is more effective in men or women?

A

Men

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7
Q

Lugol iodine staining turns inclusions brown to visualize ______.

A

Chlamydia trachomatis

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8
Q

Name 4 infections characteristic of chlamydia trachomatis.

A

Trachoma, Urogenital infection, Inclusion Conjunctivitis, Lymphogranuloma venereum

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9
Q

Name the three HPV vaccines available.

A

Gardasil, Cervarix, Gardasil-9

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10
Q

Name two key sequelae in PID caused by gonorrhea or chlamydia.

A

Infertility, Ectopic pregnancy

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11
Q

Neisseria exhibit positive oxidation of _____ but not ______.

A

glucose; maltose, sucrose

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12
Q

True or False: Men are more likely to be asymptomatic in Neisseria infection.

A

FALSE

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13
Q

True or False: Women are more likely to be infected following a single exposure to Neisseria gonorrhoeae

A

TRUE

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14
Q

What are culture requirements for growing Neisseria?

A

> 3% carbon dioxide

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15
Q

What infection may be observed in infants born to mothers infected with Neisseria gonorrhoeae?

A

Ophthalmia Neonatorum

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16
Q

What is the appropriate treatment for a patient testing positive for Neisseria gonorrhoeae infection?

A

Ceftriaxone, Azithromycin

17
Q

What is the most common notifiable disease in the US?

A

Chlamydia trachomatis

18
Q

What is the treatment for treponema pallidum

A

Penicillin

19
Q

Which diagnosis? Gummas, cardiovascular complications, meningitis, ocular involvement, tabes dorsalis

A

Tertiary syphilis

20
Q

Which diagnosis? Hutchinson teeth, nerve deafness, skeletal signs

A

Syphilis

21
Q

Which diagnosis? Mucocutaneous and skin lesions, lymphadenopathy, malaise

A

Secondary syphilis

22
Q

Which HPV gene normally suppresses E6 and E7?

A

E2

23
Q

Which HPV types are associated with condyloma acuminatum?

A

HPV6, HPV1

24
Q

Which HPV types are associated with verruca plantaris on the soles or toes?

A

HPV1, HPV2, HPV4

25
Q

Which HPV types are associated with verruca vulgaris on hands and feet?

A

HPV2, HPV7

26
Q

Which HPV types are the most strongly associated with malignant potential?

A

HPV16, HPV18

27
Q

Which pathogen? Chronic keratoconjunctivitis with acute inflammatory changes progressing to scarring and blindness

A

Chlamydia trachomatis

28
Q

Which pathogen? Gram negative diplococcus or kidney shaped single cocci

A

Neisseria

29
Q

Which pathogen? Most common cause globally of infection-induced blindness

A

Chlamydia trachomatis

30
Q

Which pathogen? Mucopurulent conjunctivitis that may cause pneumonia

A

Chlamydia trachomatis

31
Q

Which pathogen? Non-enveloped icosahedral DNA virus causing genital warts

A

HPV

32
Q

Which pathogen? Small round-oval cells (gram-negative) with biphasic life cycle

A

Chlamydia trachomatis

33
Q

Which pathogen? STD caused by long, corkscrew shaped bacilli with flagella in periplasmic space

A

Treponema pallidum

34
Q

Which phase of syphilis infection is not mediated by the organisms?

A

Tertiary syphilis

35
Q

Which proteins are important to Neisseria gonorrhoeae for attachment?

A

Opa

36
Q

Which stage of syphilis is the most infectious?

A

Primary

37
Q

Which syndrome? Small ulcer on genitalia followed by lymphadenopathy, nodes may form draining sinuses

A

Lymphogranuloma venereum

38
Q

Which virulence factors may be important in Neisseria gonorrhoeae infection?

A

Lipo-oligosaccharide, IgA protease

Infectious Disease (21 decks)

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