Hypertension and Angina Flashcards
First line diuretic for hypertension?
Hydrochlorthiazide
Control BP in pheochromocytoma?
PPL
Phenoxybenzamine. Phentolamine. Labetalol.
Vasodilator used for hypertension in preeclampsia?
Hydralazine
Hydralazine AE?
Similar drugs with same AE?
Drug induced lupus (Also tachycardia, edema, MI)
HIPP
Hydra. INH. Procainamide. Penicillamine.
Vasodilator that opens K channels causing hyperpolarization, also used in alopecia?
Minoxidil
Telogen to anagen phase to inc hair growth
Non dihydropyridine CCB used for hypertension, angina, SVT?
AE?
Verapamil (cardiac > BV)
Heart failure, AV block, sinus node depression
Dihydropyridine CCB for angina and hypertension?
Nifedipine (BV > cardiac)
AE: Pretibial edema, flushing, dizziness
Powerful parenteral vasodilator that relaxes arterial AND venous sm, usually used in hpn emergency?
Nitroprusside
Powerful parenteral vasodilator that relax arterioles only? Lead to increase in RBF
Fenoldopam
Dopamine agonist
AE: Hypotension, hypoK
ACEI for hypertension that causes cough and angioedema?
Captopril
Benefits of captopril in DM and post-MI?
Delay DM nephropathy - dec albumin excretion
Slows ventricular remodeling and increase overall survival
Common AE of ACEI and ARB?
HYPERkalemia
Dec aldosterone, lead to potassium retention
Ultrashort acting vasodilator used for cyanide poisoning?
Amyl nitrate inhaled + IV sodium nitrate + IV sodium thiosulfate
MOA of nitrates?
Release nitric oxide, inc cGMP, relax vascular smooth muscle
Side effect of amyl nitrite?
Methemoglobinemia!!
