Hyperlipidemia Drugs to Know and MOA

Question 1

Atorvastatin ( Lipitor)

Answer 1

HMG COA reductase Inhibitor

Question 2

Fluvastatin

Answer 2

HMG COA reductase Inhibitor

Question 3

Lovastatin

Answer 3

HMG COA reductase Inhibitor

Question 4

Pitavastatin

Answer 4

HMG COA reductase Inhibitor

Question 5

Pravastatin

Answer 5

HMG COA reductase Inhibitor

Question 6

Rosuvastatin ( crestor)

Answer 6

HMG COA reductase Inhibitor

Question 7

Simvastatin ( Zocor)

Answer 7

HMG COA reductase Inhibitor

Question 8

Gemfibrozil

Answer 8

Fibrates

Question 9

Fenofibrate ( tricor)

Answer 9

Fibrates

Question 10

Cholestyramine

Answer 10

Bile Acid Sequestrant

Question 11

Colesevelam

Answer 11

Bile Acid Sequestrant

Question 12

COlestipol

Answer 12

Bile Acid Sequestrant

Question 13

Ezetimibe

Answer 13

Cholesterol Absorption inhibitor

Question 14

Niacin

Answer 14

Hyperlipidemic Drug

Question 15

Docosahexanoic acid

Answer 15

Omega 3 FA

Question 16

Eicosapentanoic Acid

Answer 16

Omega 3 FA

Question 17

this class of drugs competes with HMG for the HMG CoA reductase enzyme ; lowers ic supply of cholesterol;> causes cell to increase LDL receptors on the surface > internalize circulating LDL and prevents release of VLDL

Answer 17

HMG CoA Reductase Inhibitors

Question 18

this specific drug inhibits lipolysis in adipose tissue > reduces circulating free fat; increases HDL levels; increases secretion of TPA and lowers plasma fibrinogen

Answer 18

Niacin

Question 19

this class of drugs increases expression of genes coding for proteins responsible for lipoprotein structure and function

Answer 19

fibrates

Question 20

this class of drugs binds bile acids and bile salts in the small intestine

Answer 20

bile acid binding proteins

Question 21

these drugs inhibit absorption of dietary and biliary cholesterol in the small intestine

Answer 21

cholesterol absorption inhibitors