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Pharmacology II > Hyperlipidemia Drugs to Know and MOA > Flashcards

Hyperlipidemia Drugs to Know and MOA Flashcards

1
Q

Atorvastatin ( Lipitor)

A

HMG COA reductase Inhibitor

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2
Q

Fluvastatin

A

HMG COA reductase Inhibitor

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3
Q

Lovastatin

A

HMG COA reductase Inhibitor

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4
Q

Pitavastatin

A

HMG COA reductase Inhibitor

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5
Q

Pravastatin

A

HMG COA reductase Inhibitor

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6
Q

Rosuvastatin ( crestor)

A

HMG COA reductase Inhibitor

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7
Q

Simvastatin ( Zocor)

A

HMG COA reductase Inhibitor

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8
Q

Gemfibrozil

A

Fibrates

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9
Q

Fenofibrate ( tricor)

A

Fibrates

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10
Q

Cholestyramine

A

Bile Acid Sequestrant

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11
Q

Colesevelam

A

Bile Acid Sequestrant

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12
Q

COlestipol

A

Bile Acid Sequestrant

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13
Q

Ezetimibe

A

Cholesterol Absorption inhibitor

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14
Q

Niacin

A

Hyperlipidemic Drug

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15
Q

Docosahexanoic acid

A

Omega 3 FA

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16
Q

Eicosapentanoic Acid

A

Omega 3 FA

17
Q

this class of drugs competes with HMG for the HMG CoA reductase enzyme ; lowers ic supply of cholesterol;> causes cell to increase LDL receptors on the surface > internalize circulating LDL and prevents release of VLDL

A

HMG CoA Reductase Inhibitors

18
Q

this specific drug inhibits lipolysis in adipose tissue > reduces circulating free fat; increases HDL levels; increases secretion of TPA and lowers plasma fibrinogen

A

Niacin

19
Q

this class of drugs increases expression of genes coding for proteins responsible for lipoprotein structure and function

A

fibrates

20
Q

this class of drugs binds bile acids and bile salts in the small intestine

A

bile acid binding proteins

21
Q

these drugs inhibit absorption of dietary and biliary cholesterol in the small intestine

A

cholesterol absorption inhibitors

Pharmacology II (31 decks)

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