Drugs affecting the respiratory System Flashcards
1
Q
beclomethasone
A
inhaled corticosteroids
2
Q
budesomide
A
inhaled corticosteroids
3
Q
ciclesonide
A
inhaled corticosteroids
4
Q
flunisolide
A
inhaled corticosteroids
5
Q
fluticasone ( Flovent)
A
inhaled corticosteroids
6
Q
mometasone
A
inhaled corticosteroids
7
Q
cromolyn
A
mast cell stabilizer
8
Q
montelukast ( Singulair )
A
anti-leukotriene
9
Q
zafirlukast
A
anti-leukotriene
10
Q
zileuton
A
anti-leukotriene
11
Q
albuterol
A
short acting beta 2 agonist ( bronchodilator )
12
Q
levalbuterol
A
short acting beta 2 agonist ( bronchodilator )
13
Q
pirbuterol
A
short acting beta 2 agonist ( bronchodilator )
14
Q
formoterol
A
long acting beta 2 agonist ( bronchodilator )
15
Q
indacaterol
A
long acting beta 2 agonist ( bronchodilator )
16
Q
salmeterol
A
long acting beta 2 agonist ( bronchodilator )
17
Q
ipratropium
A
other bronchodilators
18
Q
tiotropium
A
other bronchodilators
19
Q
theophylline
A
other bronchodilators
20
Q
omalizumab
A
immunoglobulin antagonists
21
Q
codeine
A
antitussive/expectorant
22
Q
dextromethorphan
A
antitussive/expectorant
23
Q
benzonatate
A
antitussive/expectorant
24
Q
Guafenesin
A
antitussive/expectorant
25
cetirizine ( Zyrtec)
antihistamine
26
diphenhydramine ( Benadryl)
antihistamine
27
fexofenadine ( Allegra)
antihistamine
28
loratadine ( Claritin)
antihistamine
29
these drugs are used for asthma; they have a rapid onset of action; no anti inflammatory effect;
beta 2 agonists
30
which beta 2 selective agonist is preferred for asthma
albuterol
31
these drugs are also used for asthma; they last at least 12 hours; slow onset of action; not used as monotherapy
long acting beta 2 agonist
32
what is the first choice drug in patients with persistent asthma
inhaled corticosteroids
33
these drugs decrease the inflammatory cascade; they reduce the hyperresponsiveness of airway smooth muscle after several months of regular use
corticosteroids
34
severe asthma requires use of which drugs
IV methylprednisolone or oral prednisone
35
this drug is an inhibitor of 5- lipooxygenase l prevents formation of leukotrienes
Zileuton
36
these specific drugs block the effects of leukotrienes
zafirlukast and montelukast
37
AE of these drugs: elevation of hepatic enzymes, HA, dyspepsia ( indigestion), increase warfarin levels
leukotriene antagonists
38
this drug is a prophylactic anti inflammatory and is also a mast cell stabilizer ( blocks release of inflammatory mediators); not useful in acute attacks ; short duration of action
cromolyn
39
these drugs are cholinergic antagonists; they block contraction of smooth muscle mediated by the vagus nerve ( block Ach receptors ); less effective than Beta 2 agonists
inhaled ipratropium or tiotropium
40
this drug is a bronchodilator ; it increases cAMP and antagonizes adenosine receptors ; decreases symptoms of chronic asthma; "traditional therapy" narrow therapeutic window ( BAD)
theophylline
41
this drug selectively binds to IgE; it decreases release of inflammatory mediators from mast cells and basophils ; very costly and is only for pts who don't respond well to other tx
omalizumab
42
this disease is a chronic irreversible obstruction of airflow
COPD
43
which combo of drugs are used in COPD
albuterol and ipratropium
44
which longer acting drugs require less frequent dosing in use for COPD
tiotropium and salmeterol
45
this is inflammation of the mucous membranes of the nose
rhinitis
46
what are the most frequently used drugs for allergic rhinitis
antihistamines
47
SE of these drugs include sedation, dry eyes and mouth, difficulty urinating, and constipation
antihistamines
48
this is an alpha agonist drug that is short acting; used in allergic rhinitis ; constricts dilated arterioles and reduces airway resistance; frequently combined with antihistamines
phenylephrine
49
SE of these drugs in treating allergic rhinitis : nasal irritation, nosebleed, sore throat, candidiasis ( thrush)
corticosteroids
50
this is a mast cell stabilizer that is useful admin. before contact with an allergen ; short duration of action; available OTC as an eye drop
cromolyn
51
which drug is approved for treatment of seasonal and perennial allergic rhinitis
montelukast
52
which drug is the gold standard for the suppression and treatment of cough
codeine
53
the MOA of this drug: decreases sensitivity of cough ; enters in the CNS to peripheral stimuli; decreases mucosal secretion
codeine
54
this drug is a synthetic derivative of morphine; low addictive profile; used in the tx of cough
dextromethorphan
55
this drug is a local anesthetic for the tx of cough; it anesthetizes the respiratory passage and pleural stretch receptors and reduces cough reflex
benzonatate
56
this drug is a type of expectorant which is used in the tx of cough; it reduces adhesiveness and surface tension of respiratory tract secretions
guafinesin
57
these drugs facilitate the coughing up of mucuous
expectorants
