Drugs affecting the respiratory System

Question 1

beclomethasone

Answer 1

inhaled corticosteroids

Question 2

budesomide

Answer 2

inhaled corticosteroids

Question 3

ciclesonide

Answer 3

inhaled corticosteroids

Question 4

flunisolide

Answer 4

inhaled corticosteroids

Question 5

fluticasone ( Flovent)

Answer 5

inhaled corticosteroids

Question 6

mometasone

Answer 6

inhaled corticosteroids

Question 7

cromolyn

Answer 7

mast cell stabilizer

Question 8

montelukast ( Singulair )

Answer 8

anti-leukotriene

Question 9

zafirlukast

Answer 9

anti-leukotriene

Question 10

zileuton

Answer 10

anti-leukotriene

Question 11

albuterol

Answer 11

short acting beta 2 agonist ( bronchodilator )

Question 12

levalbuterol

Answer 12

short acting beta 2 agonist ( bronchodilator )

Question 13

pirbuterol

Answer 13

short acting beta 2 agonist ( bronchodilator )

Question 14

formoterol

Answer 14

long acting beta 2 agonist ( bronchodilator )

Question 15

indacaterol

Answer 15

long acting beta 2 agonist ( bronchodilator )

Question 16

salmeterol

Answer 16

long acting beta 2 agonist ( bronchodilator )

Question 17

ipratropium

Answer 17

other bronchodilators

Question 18

tiotropium

Answer 18

other bronchodilators

Question 19

theophylline

Answer 19

other bronchodilators

Question 20

omalizumab

Answer 20

immunoglobulin antagonists

Question 21

codeine

Answer 21

antitussive/expectorant

Question 22

dextromethorphan

Answer 22

antitussive/expectorant

Question 23

benzonatate

Answer 23

antitussive/expectorant

Question 24

Guafenesin

Answer 24

antitussive/expectorant

Question 25

cetirizine ( Zyrtec)

Answer 25

antihistamine

Question 26

diphenhydramine ( Benadryl)

Answer 26

antihistamine

Question 27

fexofenadine ( Allegra)

Answer 27

antihistamine

Question 28

loratadine ( Claritin)

Answer 28

antihistamine

Question 29

these drugs are used for asthma; they have a rapid onset of action; no anti inflammatory effect;

Answer 29

beta 2 agonists

Question 30

which beta 2 selective agonist is preferred for asthma

Answer 30

albuterol

Question 31

these drugs are also used for asthma; they last at least 12 hours; slow onset of action; not used as monotherapy

Answer 31

long acting beta 2 agonist

Question 32

what is the first choice drug in patients with persistent asthma

Answer 32

inhaled corticosteroids

Question 33

these drugs decrease the inflammatory cascade; they reduce the hyperresponsiveness of airway smooth muscle after several months of regular use

Answer 33

corticosteroids

Question 34

severe asthma requires use of which drugs

Answer 34

IV methylprednisolone or oral prednisone

Question 35

this drug is an inhibitor of 5- lipooxygenase l prevents formation of leukotrienes

Answer 35

Zileuton

Question 36

these specific drugs block the effects of leukotrienes

Answer 36

zafirlukast and montelukast

Question 37

AE of these drugs: elevation of hepatic enzymes, HA, dyspepsia ( indigestion), increase warfarin levels

Answer 37

leukotriene antagonists

Question 38

this drug is a prophylactic anti inflammatory and is also a mast cell stabilizer ( blocks release of inflammatory mediators); not useful in acute attacks ; short duration of action

Answer 38

cromolyn

Question 39

these drugs are cholinergic antagonists; they block contraction of smooth muscle mediated by the vagus nerve ( block Ach receptors ); less effective than Beta 2 agonists

Answer 39

inhaled ipratropium or tiotropium

Question 40

this drug is a bronchodilator ; it increases cAMP and antagonizes adenosine receptors ; decreases symptoms of chronic asthma; “traditional therapy” narrow therapeutic window ( BAD)

Answer 40

theophylline

Question 41

this drug selectively binds to IgE; it decreases release of inflammatory mediators from mast cells and basophils ; very costly and is only for pts who don’t respond well to other tx

Answer 41

omalizumab

Question 42

this disease is a chronic irreversible obstruction of airflow

Answer 42

COPD

Question 43

which combo of drugs are used in COPD

Answer 43

albuterol and ipratropium

Question 44

which longer acting drugs require less frequent dosing in use for COPD

Answer 44

tiotropium and salmeterol

Question 45

this is inflammation of the mucous membranes of the nose

Answer 45

rhinitis

Question 46

what are the most frequently used drugs for allergic rhinitis

Answer 46

antihistamines

Question 47

SE of these drugs include sedation, dry eyes and mouth, difficulty urinating, and constipation

Answer 47

antihistamines

Question 48

this is an alpha agonist drug that is short acting; used in allergic rhinitis ; constricts dilated arterioles and reduces airway resistance; frequently combined with antihistamines

Answer 48

phenylephrine

Question 49

SE of these drugs in treating allergic rhinitis : nasal irritation, nosebleed, sore throat, candidiasis ( thrush)

Answer 49

corticosteroids

Question 50

this is a mast cell stabilizer that is useful admin. before contact with an allergen ; short duration of action; available OTC as an eye drop

Answer 50

cromolyn

Question 51

which drug is approved for treatment of seasonal and perennial allergic rhinitis

Answer 51

montelukast

Question 52

which drug is the gold standard for the suppression and treatment of cough

Answer 52

codeine

Question 53

the MOA of this drug: decreases sensitivity of cough ; enters in the CNS to peripheral stimuli; decreases mucosal secretion

Answer 53

codeine

Question 54

this drug is a synthetic derivative of morphine; low addictive profile; used in the tx of cough

Answer 54

dextromethorphan

Question 55

this drug is a local anesthetic for the tx of cough; it anesthetizes the respiratory passage and pleural stretch receptors and reduces cough reflex

Answer 55

benzonatate

Question 56

this drug is a type of expectorant which is used in the tx of cough; it reduces adhesiveness and surface tension of respiratory tract secretions

Answer 56

guafinesin

Question 57

these drugs facilitate the coughing up of mucuous

Answer 57

expectorants