Diuretics Drugs to KNow and MOA

Question 1

these drugs have major action on the ascending limb of loop of henle ; they inhibit co transport of Na/K/2Cl -> reabsorption is decreased

Answer 1

loop diuretics

Question 2

these drugs inhibit carbonic anhydrase in the proximal tubule; carbonic anhydrase catalyzes reaction to form bicarbonate

Answer 2

carbonic anhydrase inhibitor

Question 3

mannitol

Answer 3

osmotic diuretics

Question 4

these drugs increase urine flow

Answer 4

diuretics

Question 5

furosemide ( Lasix)

Answer 5

loop diuretic

Question 6

the drugs act in the collecting tubule; they inhibit the Na reabsorption and K excretion; also block aldosterone receptors ( aldosterone antagonists)

Answer 6

K sparing diuretics

Question 7

HCTZ

Answer 7

thiazide diuretic

Question 8

chlorthalidone

Answer 8

thiazide diuretic

Question 9

Bumetanide

Answer 9

Loop diuretic

Question 10

acetazolamide

Answer 10

carbonic anhydrase inhibitors

Question 11

these drugs affect the distal tubule; the inhibit the Na/Cl cotransporter -> increases concentration of Na and Cl in tubular fluid

Answer 11

thiazide diuretics

Question 12

ethacrynic acid

Answer 12

loop diuretic

Question 13

torsemide

Answer 13

loop diuretic

Question 14

spironalactone

Answer 14

K sparing diuretics

Question 15

these drugs are filtered through the glomerulus and carry water with them; increase water excretion

Answer 15

osmotic diuretics

Question 16

methazolamide

Answer 16

carbonic anhydrase inhibitors

Question 17

Metolazone

Answer 17

thiazide diuretic

Question 18

Indapamide

Answer 18

thiazide diuretic

Question 19

eplenerone

Answer 19

K sparing diuretics