Adrenal Hormones Flashcards
betamethasone
corticosteroid
cortisone
corticosteroid
dexamethasone
corticosteroid
fludrocortisone
corticosteroid
hydrocortisone
corticosteroid
methylprednisolone
corticosteroid
prednisolone
corticosteroid
prednisone
corticosteroid
triamcinolone
corticosteroid
eplenerone
inhibitor of adrenocorticoid biosynthesis
ketoconazole
inhibitor of adrenocorticoid biosynthesis
spironolactone
inhibitor of adrenocorticoid biosynthesis
these drugs bind to specific ic cytoplasmic receptors ; the receptor hormone complex regulates gene transcription
adrenocorticosteroids
what Is the most important property for glucocorticoids
anti-inflammatory ( these drugs also cause increase in IOP)
this drug is given to correct Addisons Disease ( primary, secondary, and tertiary)
hydrocortisone ( fludrocortisone may also be required)
which drug is used as a suppression test for Cushings Syndrome
dexamethasone
this disease is caused by adrenal cortex dysfunction
Addison disease ( primary adrenocortical insufficiency)
this syndrome is caused by hypersecretion of glucocorticoids
cushing syndrome
this results from enzyme defect in the synthesis of adrenal hormones
congenital adrenal hyperplasia
which drug is a regulator of lung maturation
fetal cortisol ( bexamethasone or dexamethasone)
which steroid is preferred in pregnancy
prednisone ( minimizes effect on the fetus)
adverse effects of these drugs include increased IOP, decreased growth in kids, glaucoma, centripetal dist. of fat, osteoporosis, increased risk of infection, and hirsutism( increased hair growth), increased appetite, emotional disturbances, peptic ulcer, hypertension, peripheral edema, and hypokalemia
adrenal corticosteroids
this drug is an inhibitor of adrenocorticosteroid biosynthesis and function; it strongly inhibits all gonadal and adrenal steroid hormone synthesis; its also an antifungal and is used to treat Cushing Syndrome
ketoconazole
this drug is an inhibitor of adrenocorticosteroid biosynthesis and function; it is an antihypertensive that competes for mineralocorticoid receptor
spironolactone