Diabetes Flashcards

1
Q

Insulin

A

Know these are short acting and long acting

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2
Q

acarbose

A

alpha glucosidase inhibitor

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3
Q

miglitol

A

alpha glucosidase inhibitor

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4
Q

linagliptin

A

DPP-4 inhibitors

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5
Q

saxagliptin

A

DPP-4 inhibitors

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6
Q

sitagliptin

A

DPP-4 inhibitors

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7
Q

exenatide

A

GLP-1 inhibitors

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8
Q

liraglutide

A

GLP-1 inhibitors

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9
Q

nateglinide

A

meglitinide

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10
Q

repaglinide

A

meglitinide

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11
Q

glimepiride

A

sulfonylurea

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12
Q

glipizide

A

sulfonylurea

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13
Q

glyburide

A

sulfonylurea

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14
Q

pioglitazone

A

thiazolidinedione

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15
Q

rosiglitazone

A

thiazolidinedione

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16
Q

metformin

A

other diabetic drugs

17
Q

pramlintide

A

other diabetic drugs

18
Q

canagliflozin

A

glucuretic

19
Q

empagliflozin

A

glucuretic

20
Q

this specific drug is used as an adjunct to mealtime insulin; delays gastric emptying

A

pramlintide

21
Q

these drugs stimulate insulin secretion from the beta cells; they bind to receptors in the beta cells causing K channels to close ( depolarization) Ca channels then open ( controls release of insulin)

A

sulfonylureas

22
Q

Side effects of this class of drugs includes hypoglycemia, skin reactions, weight gain, cardiac side effects

A

sulfonylureas

23
Q

this class of drugs are developed to decrease postprandial hyperglycemia ; bind to same beta cell as sulfonylureas-> cause similar release of insulin

A

meglitinides

24
Q

Side effects of this class of drugs is less risk for hypoglycemia ; small amt of weight gain

A

meglitinides

25
Q

which drug is the drug of choice for type II patients

A

metformin

26
Q

MOA of this specific drug increases hepatic sensitivity to insulin; increases insulin stimulated glucose uptake in skeletal muscle ; suppresses the oxidation of FA and reduces triglyceride levels

A

metformin

27
Q

this class of drug improves the whole bodys sensitivity to insulin; it stimulates receptor in adipose tissue ( also in muscle and liver)

A

thiazolidinediones

28
Q

these drugs SE can cause fluid retention ; avoid in pts with liver disease; combo with insulin may increase risk of heart failure;

A

thiazolidinediones

29
Q

these drugs target the alpha glucosidase enzymes

A

alpha glucosidase inhibitors

30
Q

SE of these drugs include flatulence, diarrhea, and abdominal cramping

A

alpha glucosidase inhibitors

31
Q

SE of this drugs include upper respiratory infections, HA, pancreatitis, severe allergic reactions

A

DPP IV inhibitors

32
Q

these drugs inhibit DPP IV;

A

DPP IV inhibitors

33
Q

these drugs bind to GLP 1 receptors and help restore activity

A

Glucagon like polypeptide 1 agonists

34
Q

SE of these drugs includes HA, nausea, diarrhea, immune reactions, and pancreatitis

A

glucagon like polypeptide 1 agonists

35
Q

this glucagon like poly. pep agonists is CI in pts with a fam Hx of Cx

A

liraglutide

36
Q

these drugs inhibit the activity of the Na Glucose cotransporter 2-> results in an increase in urinary glucose excretion

A

Na Glucose cotransporter inhibitors

37
Q

SE of this class of drugs includes UTIs and yeast infections, urinary frequency, and hypotension

A

Na glucose cotransporter inhibitors