Diabetes Flashcards
Insulin
Know these are short acting and long acting
acarbose
alpha glucosidase inhibitor
miglitol
alpha glucosidase inhibitor
linagliptin
DPP-4 inhibitors
saxagliptin
DPP-4 inhibitors
sitagliptin
DPP-4 inhibitors
exenatide
GLP-1 inhibitors
liraglutide
GLP-1 inhibitors
nateglinide
meglitinide
repaglinide
meglitinide
glimepiride
sulfonylurea
glipizide
sulfonylurea
glyburide
sulfonylurea
pioglitazone
thiazolidinedione
rosiglitazone
thiazolidinedione
metformin
other diabetic drugs
pramlintide
other diabetic drugs
canagliflozin
glucuretic
empagliflozin
glucuretic
this specific drug is used as an adjunct to mealtime insulin; delays gastric emptying
pramlintide
these drugs stimulate insulin secretion from the beta cells; they bind to receptors in the beta cells causing K channels to close ( depolarization) Ca channels then open ( controls release of insulin)
sulfonylureas
Side effects of this class of drugs includes hypoglycemia, skin reactions, weight gain, cardiac side effects
sulfonylureas
this class of drugs are developed to decrease postprandial hyperglycemia ; bind to same beta cell as sulfonylureas-> cause similar release of insulin
meglitinides
Side effects of this class of drugs is less risk for hypoglycemia ; small amt of weight gain
meglitinides
which drug is the drug of choice for type II patients
metformin
MOA of this specific drug increases hepatic sensitivity to insulin; increases insulin stimulated glucose uptake in skeletal muscle ; suppresses the oxidation of FA and reduces triglyceride levels
metformin
this class of drug improves the whole bodys sensitivity to insulin; it stimulates receptor in adipose tissue ( also in muscle and liver)
thiazolidinediones
these drugs SE can cause fluid retention ; avoid in pts with liver disease; combo with insulin may increase risk of heart failure;
thiazolidinediones
these drugs target the alpha glucosidase enzymes
alpha glucosidase inhibitors
SE of these drugs include flatulence, diarrhea, and abdominal cramping
alpha glucosidase inhibitors
SE of this drugs include upper respiratory infections, HA, pancreatitis, severe allergic reactions
DPP IV inhibitors
these drugs inhibit DPP IV;
DPP IV inhibitors
these drugs bind to GLP 1 receptors and help restore activity
Glucagon like polypeptide 1 agonists
SE of these drugs includes HA, nausea, diarrhea, immune reactions, and pancreatitis
glucagon like polypeptide 1 agonists
this glucagon like poly. pep agonists is CI in pts with a fam Hx of Cx
liraglutide
these drugs inhibit the activity of the Na Glucose cotransporter 2-> results in an increase in urinary glucose excretion
Na Glucose cotransporter inhibitors
SE of this class of drugs includes UTIs and yeast infections, urinary frequency, and hypotension
Na glucose cotransporter inhibitors