Heart Failure Drugs to Know and MOA

Question 1

isosorbide dinitrate

Answer 1

vasodilator

Question 2

inamrione

Answer 2

inotrope

Question 3

these drugs cause positive inotropic effects and vasodilation -> increases cAMP which activates protein kinase

Answer 3

beta adrenergic agonists ( inotropic drugs)

Question 4

this drug inhibits the ability of the monocyte to actively pump Na from the cell -> decreased Na concentration gradient decreases the exchange with Ca-> more Ca remains inside the monocyte and is stored in SR ( increases cardiac contractility)

Answer 4

digoxin ( inotropic drug)

Question 5

milrinone

Answer 5

inotrope

Question 6

spironolactone

Answer 6

aldosterone antagonists

Question 7

nebivolol

Answer 7

beta 1 selective

Question 8

this drug slows down conduction velocity through AV node ( can be used in atrial fibrillation)

Answer 8

digoxin

Question 9

nitroprusside

Answer 9

vasodilator

Question 10

these drugs prevent salt retention, myocardial hypertrophy, and hypokalemia

Answer 10

aldosterone antagonists

Question 11

metoprolol

Answer 11

beta 1 selective

Question 12

eplenerone

Answer 12

aldosterone antagonists

Question 13

dopamine

Answer 13

beta agonist

Question 14

these drugs enhance cardiac muscle contractility-> increases cardiac output; all increase cytoplasmic Ca concentration

Answer 14

positive inotropic drugs

Question 15

these drugs prevent hydrolysis of cAMP-

Answer 15

inotropic drugs ( phosphodiesterase inhibitors)

Question 16

dobutamine

Answer 16

beta agonist

Question 17

digoxin

Answer 17

inotrope

Question 18

hydralazine

Answer 18

vasodilator