Drugs Targeting Central Gabaergic Systems Flashcards
Disulfiram
Tx of Alcohol Dependence
Side effects of these drugs include: amnesia, daytime sedation, disinhibition, bizarre behavior ( hallucinations); in the absence of other drugs this is not lethal ,
benzodiazepenes
Midazolam ( Versed)
Benzodiazepines
these drugs also decrease the release of GABA
Benzodiazepines
Secobarbital
Barbiturate
Flumazenil
Benzodiazepine Antagonist
Diazepam ( Valium)
Benzodiazepines
Clonazepam ( Klonopin)
Benzodiazepines
Oxazepam
Benzodiazepines
Temazepam
Benzodiazepines
Zaleplon ( Sonata)
Other Hypnotic Drugs ( Benzo Like)
Pentobarbital ( Nembutal )
Barbiturate
MOA of these drugs : binding to receptor increases the affinity of GABA for its receptor
Ethanol, Benzodiazepines, and barbiturates
Ramelteon ( Rozerem)
Other Hypnotic Drugs ( Melatonin Receptor Agonist)
actions of this class of drugs includes : CNS depression, respiratory depression, enzyme induction
barbiturates
Chlordiazepoxide ( Librium)
Benzodiazepines
side effects of this class of drugs includes sedation, addiction, hypotension with IV use, can be lethal in overdose even in the absence of any other drugs
barbiturates
Buspirone
Other Anxiolytic Drug
Clorazepate
Benzodiazepines
Triazolam
Benzodiazepines
Naltrexone
Tx of Alcohol Dependence
Estazolam
Benzodiazepines
Lorazepam
Benzodiazepines
this class of drugs actions includes: reduces anxiety, sedative and hypnotic, anterograde amnesia, anticonvulsant, and muscle relaxant
Benzodiazepines
Acamprosate
Tx of Alcohol Dependence
Zolpidem ( Ambien)
Other Hypnotic Drugs ( Benzo Like)
Phenobarbital
Barbiturate
Eszopiclone ( Lunesta)
Other Hypnotic Drugs ( Benzo Like)
this specific drug is a melatonin receptor agonist; involved with liver metabolism
ramelteon
Flurazepam
Benzodiazepines
this specific drug inhibits aldehyde dehydrogenase
disulfiram
Alprazolam ( Xanax)
Benzodiazepines