Drugs Targeting Central Gabaergic Systems Flashcards

1
Q

Disulfiram

A

Tx of Alcohol Dependence

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2
Q

Side effects of these drugs include: amnesia, daytime sedation, disinhibition, bizarre behavior ( hallucinations); in the absence of other drugs this is not lethal ,

A

benzodiazepenes

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3
Q

Midazolam ( Versed)

A

Benzodiazepines

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4
Q

these drugs also decrease the release of GABA

A

Benzodiazepines

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5
Q

Secobarbital

A

Barbiturate

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6
Q

Flumazenil

A

Benzodiazepine Antagonist

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7
Q

Diazepam ( Valium)

A

Benzodiazepines

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8
Q

Clonazepam ( Klonopin)

A

Benzodiazepines

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9
Q

Oxazepam

A

Benzodiazepines

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10
Q

Temazepam

A

Benzodiazepines

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11
Q

Zaleplon ( Sonata)

A

Other Hypnotic Drugs ( Benzo Like)

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12
Q

Pentobarbital ( Nembutal )

A

Barbiturate

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13
Q

MOA of these drugs : binding to receptor increases the affinity of GABA for its receptor

A

Ethanol, Benzodiazepines, and barbiturates

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14
Q

Ramelteon ( Rozerem)

A

Other Hypnotic Drugs ( Melatonin Receptor Agonist)

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15
Q

actions of this class of drugs includes : CNS depression, respiratory depression, enzyme induction

A

barbiturates

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16
Q

Chlordiazepoxide ( Librium)

A

Benzodiazepines

17
Q

side effects of this class of drugs includes sedation, addiction, hypotension with IV use, can be lethal in overdose even in the absence of any other drugs

A

barbiturates

18
Q

Buspirone

A

Other Anxiolytic Drug

19
Q

Clorazepate

A

Benzodiazepines

20
Q

Triazolam

A

Benzodiazepines

21
Q

Naltrexone

A

Tx of Alcohol Dependence

22
Q

Estazolam

A

Benzodiazepines

23
Q

Lorazepam

A

Benzodiazepines

24
Q

this class of drugs actions includes: reduces anxiety, sedative and hypnotic, anterograde amnesia, anticonvulsant, and muscle relaxant

A

Benzodiazepines

25
Q

Acamprosate

A

Tx of Alcohol Dependence

26
Q

Zolpidem ( Ambien)

A

Other Hypnotic Drugs ( Benzo Like)

27
Q

Phenobarbital

A

Barbiturate

28
Q

Eszopiclone ( Lunesta)

A

Other Hypnotic Drugs ( Benzo Like)

29
Q

this specific drug is a melatonin receptor agonist; involved with liver metabolism

A

ramelteon

30
Q

Flurazepam

A

Benzodiazepines

31
Q

this specific drug inhibits aldehyde dehydrogenase

A

disulfiram

32
Q

Alprazolam ( Xanax)

A

Benzodiazepines