Fluid Imbalance lecture Flashcards
1L = ? of water in the body
1L = 2.2 lbs
normal plasma osmolality level; number meaning associated with water excess or deficit
275-295 mOsm/kg
below -> water excess
above -> water deficit -> solute conc. increase
what are the electrolytes in and outside of the cell?
IN: K, PO4, Mg
OUT: Na, Cl, Ca, HCO3
what are some relationship with electrolytes IN and OUT of the cell
Na with K
Ca with PO4
INVERSE relationship
what is moving during diffusion
solutes move from low to high concentration
what are the electrolytes and molecules that require active transport
Na, K, Ca, H, amino acids, and some sugars
what is osmosis
water moves from low concentration solutes to high concentration solutes
osmolarity vs. osmolality
osmolarity: total solute per unit fluit outside the body; mOsm/L
osmolality: osmatic force per solvent within the vascular system; mOsm/kg
how does estimating serum osmolality work
add up all the electrolyte lab numbers;
doesn’t work for someone with abnormal glucose
urine osmolality level
100-1300 mOsm/kg
isotonic vs. hypotonic vs. hypertonic
isotonic: fluid will remain in vascular space
hypotonic: fluid leaves vascular space into cells (leading to edema)
hypertonic: fluid goes into vascular space from cells
what are the isotonic fluids
- normal saline - 0.9% NaCl
- lactated ringers
- D5W
what is normal saline 0.9% NaCl fluid used for
Big idea: expands intravascular volume/space
* shock
* hyponatremia, hypocalcemia
* blood transfusions
* increase BP, replace fluids
what is lactated ringers fluid used for
Big idea: rehydrating most types of dehydration
* burns
* acute blood loss
* hypovolemia due to 3rd spacing
* lower GI loss - N&V&D
what is D5W used for
fluid loss from dehydration
hypernatremia
what is a hypotonic fluid
1/2 NS (0.45% NaCl)
what is 1/2 NS (0.45% NaCl) fluid used for
water replacement
diabetic ketoacidosis after initial normal saline
hypertonic dehydration
gastric fluid loss (NG, V)
what are the hypertonic fluids
- dextrose 5% in 1/2 normal saline
- dextrose 5% in normal saline
- dextrose 5% in lactated ringers
dextrose 5% in 1/2 normal saline usage
- severe dehydration
- expands plasma volume
- burns
- diabetic ketoacidosis after NS and 1/2 NS
dextrose 5% in NS usage
- hypotonic dehydration
- temp fluid replacement in shock