Endocrine glands I Flashcards
Which pituitary lobe is neural?
Posterior
Which pituitary lobe is glandular?
Anterior
What are the anterior pituitary secretory cells?
- Chromophils2. Chromophobes
Where are the hypothalamic neurosecretory hormones synthesized?
Neurons in the hypothalamus
Where are the hypothalamic neurosecretory hormones stored?
Axons of neurons in hypothalamus, which terminate at median eminence
What is the direction of flow of hypothalamic neurosecretory hormones after being released at median eminence?
- Primary capillary plexus (fenestrated capillaries)2. Hypophyseal portal veins in infundibulum3. Secondary capillary plexus (sinusoidal with fenestrated endothelium - anterior lobe)4. Parenchyma of anterior lobe
What are housed in the supraoptic and paraventricular nuclei of the hypothalamus?
Cell bodies of neurosecretory cells
Where are the cell bodies of neurosecretory cells housed?
Supraoptic and paraventricular nuclei of hypothalamus
What makes up the hypothalamohypophyseal tract?
The unmyelinated axons of neurosecretory cells in the supraoptic and paraventricular nuclei
Where does the hypothalamohypophyseal tract terminate?
Capillaries in the posterior lobe of pituitary
What does the hypothalamohypophyseal tract release into the capillaries of the posterior pituitary?
ADH and oxytocin
The anterior pituitary has what kind of capillaries?
Fenestrated sinudoidal
What are the chromophils of the anterior pituitary?
- Acidophils2. Basophils
What are the different types of acidophils?
- Somatotropes2. Lactotropes
What stimulates somatotrope production?
GHRH
What inhibits somatotropes?
Somatostatin
What do somatotropes secrete?
Growth hormone
What is the role of growth hormone?
Increases metabolic rate and influences long bone growth
What stimulates lactotrope production?
PRH
What inhibits lactotropes?
PIF
What do lactotropes secrete?
Prolactin which promotes mamary gland growth during pregnancy and lactation after birth
What are the types of basophils?
- Corticotropes2. Thyrotropes3. Gonadotropes
What stimulates corticotrope production?
CRH